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ClinicalTrials.gov public records Last synced Oct 11, 2026, 3:45 PM EDT

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Showing 265–288 of 7,891 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Musculoskeletal Disease Clear all
Withdrawn No phase listed Observational Accepts healthy volunteers

Study of the Associations Between Subchondral Insufficiency Fractures of the Knee and Pre-existing Health, Lifestyle, and/or Musculoskeletal Conditions

NCT04953702
View directory record Official record
Conditions
Subchondral Insufficiency Fracture
Interventions
Not listed
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 11, 2026, 3:45 PM EDT
Completed No phase listed Observational

Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials

NCT00584272
View directory record Official record
Conditions
Cleft Palate
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
1 Year to 10 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 11, 2026, 3:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal

NCT07673328
View directory record Official record
Conditions
Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
Interventions
Modular powered orthosis
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Phase 2 Interventional

A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee

NCT01444365
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
ABT-652 NSAID, Placebo NSAID
Drug
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
40 Years to 75 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
31
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 27 more
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Oct 11, 2026, 3:45 PM EDT
Active, not recruiting Not applicable Interventional

Avenir Complete Post-Market Clinical Follow-Up Study

NCT04731077
View directory record Official record
Conditions
Osteoarthritis, Hip, Avascular Necrosis of Hip, Avascular Necrosis of the Femoral Head, Post-traumatic; Arthrosis
Interventions
Avenir Complete Femoral Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2036
U.S. locations
3
States / cities
Jackson, Mississippi • Saint Joseph, Missouri • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 11, 2026, 3:45 PM EDT
Completed No phase listed Observational Results available

Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output

NCT05070572
View directory record Official record
Conditions
Intra-Abdominal Hypertension, Inguinal Hernia
Interventions
Accuryn Monitoring System
Device
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Explosive Synchronization of Brain Network Activity in Chronic Pain

NCT04606095
View directory record Official record
Conditions
Fibromyalgia, Healthy Volunteers
Interventions
EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3)
Diagnostic Test · Device
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 74 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of RHH646 for Knee Osteoarthritis

NCT05816395
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
RHH646, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
35 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Lincoln, California • Winter Park, Florida • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Not listed No phase listed Observational

Clinical Outcome Study for Dysferlinopathy

NCT01676077
View directory record Official record
Conditions
Dysferlinopathy, LGMD2B Now Classified as LGMDR2, Miyoshi Myopathy
Interventions
Not listed
Lead sponsor
Newcastle-upon-Tyne Hospitals NHS Trust
Other
Eligibility
10 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
6
States / cities
Orange, California • Palo Alto, California • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Not applicable Interventional Results available

Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee

NCT00126737
View directory record Official record
Conditions
Chronic Diseases, Obesity, Osteoarthritis, Pain
Interventions
Weight Control Nutritional Program, Home-based exercise program
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 1, 2015 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Phase 3 Interventional Results available

Pamidronate to Treat Osteogenesis Imperfecta in Children

NCT00005901
View directory record Official record
Conditions
Osteogenesis Imperfecta
Interventions
Pamidronate (Aredia)
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Up to 16 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 1, 2016 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Not applicable Interventional Results available

Outcomes of CPM Usage Following Arthroscopic Acetabular Labral Repair

NCT03407612
View directory record Official record
Conditions
Femoro Acetabular Impingement, Pain, Postoperative, Hip Labral Tear
Interventions
Continuous Passive Motion
Device
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 11, 2026, 3:45 PM EDT
Withdrawn No phase listed Observational

Activity of Pre-Osteoclasts and Osteoclasts Over Time in Postmenopausal Women Treated With Denosumab or Zoledronic Acid

NCT03812367
View directory record Official record
Conditions
Osteoporosis, Postmenopausal
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 11, 2026, 3:45 PM EDT
Not yet recruiting No phase listed Observational

Insights Into Participating in Studies for Bone Cancer

NCT06070259
View directory record Official record
Conditions
Bone Cancer
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 11, 2026, 3:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

OTIS Humira Pregnancy Registry

NCT01086059
View directory record Official record
Conditions
Crohn's Disease, Rheumatoid Arthritis
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
Female only
Enrollment
944 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 11, 2026, 3:45 PM EDT
Completed No phase listed Observational

Initial Validation of PROMIS Physical Function/Disability Scales in Rheumatoid Arthritis (RA)

NCT00786227
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
761 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 3, 2013 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Not applicable Interventional Results available

A Direct-to-patient Intervention to Increase Rates of Osteoporosis Care

NCT01907269
View directory record Official record
Conditions
Osteoporosis
Interventions
Video-based Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older · Female only
Enrollment
2,684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
7
States / cities
Birmingham, Alabama • Los Angeles, California • Worcester, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 11, 2026, 3:45 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers

NCT03571594
View directory record Official record
Conditions
Acromegaly
Interventions
ONO-5788, ONO-5788 Placebo, Octreotide
Drug
Lead sponsor
Ono Pharmaceutical Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Oct 11, 2026, 3:45 PM EDT
Completed No phase listed Observational Results available

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

NCT06418529
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
tofacitinib, tumor necrosis factor inhibitors (TNFi), abatacept, tocilizumab or sarilumab
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
21,340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 11, 2026, 3:45 PM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Safety Study of SUNPG1622

NCT02980705
View directory record Official record
Conditions
Active Ankylosing Spondylitis or Non-Radiographic Axial Spondyloarthritis
Interventions
SUNPG1622 I dose, Placebo dose
Drug
Lead sponsor
Sun Pharmaceutical Industries Limited
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Middleburg Heights, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 11, 2026, 3:45 PM EDT
Recruiting No phase listed Observational

Duchenne Electronic Health Record Study

NCT07609394
View directory record Official record
Conditions
Duchenne Muscular Dystrophy (DMD), Becker Muscular Dystrophy, Dystrophinopathy, Dystrophinopathy Symptomatic Female Carrier
Interventions
Observational study with patients who may be treated with various disease-modifying therapies
Other
Lead sponsor
The Duchenne Registry
Other
Eligibility
Not listed
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2072
U.S. locations
10
States / cities
Little Rock, Arkansas • Sacramento, California • Aurora, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Psoriatic Arthritis Study of Izokibep

NCT05623345
View directory record Official record
Conditions
Psoriatic Arthritis
Interventions
Izokibep, Placebo to izokibep
Drug
Lead sponsor
ACELYRIN Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
40
States / cities
Flagstaff, Arizona • Glendale, Arizona • Mesa, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated May 23, 2025 · Synced Oct 11, 2026, 3:45 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

NCT04378075
View directory record Official record
Conditions
Mitochondrial Diseases, Drug Resistant Epilepsy, Leigh Disease, Leigh Syndrome, Mitochondrial Encephalopathy (MELAS), Pontocerebellar Hypoplasia Type 6 (PCH6), Alpers Disease, Alpers Syndrome
Interventions
Vatiquinone, Placebo
Drug · Other
Lead sponsor
PTC Therapeutics
Industry
Eligibility
Up to 20 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
12
States / cities
San Diego, California • Stanford, California • New Haven, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 11, 2026, 3:45 PM EDT
Completed Not applicable Interventional Results available

Low Intensity Ultrasound Therapy for Upper Back Pain Relief

NCT02135094
View directory record Official record
Conditions
Muscle Spasm
Interventions
Active ultrasound therapy device, Placebo ultrasound therapy device
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Trumbull, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 11, 2026, 3:45 PM EDT