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ClinicalTrials.gov public records Last synced Sep 30, 2026, 12:53 AM EDT

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Showing 25–48 of 65 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Musculoskeletal Neck Pain Clear all
Completed Not applicable Interventional

Noxipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation for Chronic Pain

NCT01578148
View directory record Official record
Conditions
Shoulder Pain, Neck Pain
Interventions
Noxipoint Therapy, Physical Therapy
Procedure
Lead sponsor
Pain Cure Center, California
Industry
Eligibility
18 Years to 64 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional

Effects of Cervical Manual Therapy on Cervicogenic Headache

NCT03385889
View directory record Official record
Conditions
Unilateral Headache, Musculoskeletal Neck Pain
Interventions
Cervical Spine Mobilization, Cervical Spine Manipulation
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Sep 30, 2026, 12:53 AM EDT
Completed No phase listed Observational

Adverse Events in Dry Needling

NCT03612843
View directory record Official record
Conditions
Muscle Soreness, Headache, Knee Osteoarthritis, Back Pain, Neck Pain, Needle Stick, Shoulder Pain, Hip Osteoarthritis
Interventions
Observational dry needle
Other
Lead sponsor
Elizabeth Lane
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
8
States / cities
Acworth, Georgia • Cartersville, Georgia • Fort Oglethorpe, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 30, 2026, 12:53 AM EDT
Active, not recruiting Not applicable Interventional

EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief

NCT07661121
View directory record Official record
Conditions
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
Interventions
Treatment with BTL-043 and BTL-785F
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Leesburg, Florida • Ocala, Florida • Covington, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Phase 2 Interventional

Healing With Venlafaxine After Injury (HELP)

NCT01716377
View directory record Official record
Conditions
Neck Pain
Interventions
Venlafaxine
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Grand Rapids, Michigan • Rochester, New York • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 30, 2026, 12:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain

NCT00134225
View directory record Official record
Conditions
Neck Pain, Low Back Pain
Interventions
Muscle Pattern Recognition (MPR)
Device
Lead sponsor
iTech Medical, Inc.
Industry
Eligibility
18 Years to 62 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
3
States / cities
Irvine, California • Portage, Michigan • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 26, 2005 · Synced Sep 30, 2026, 12:53 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

ATI Evidence-based Guide Investigating Clinical Services

NCT02285868
View directory record Official record
Conditions
Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle, Hip, Elbow, Neurological, Vestibular, Pelvic Floor, TMJ, Fibromyalgia, Headaches, Lymphedema
Interventions
Not listed
Lead sponsor
ATI Holdings, LLC
Industry
Eligibility
Not listed
Enrollment
4,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Tissue Response to High-Velocity Thrust Manipulations on Capsule Length and Stiffness at the C5-C6 Facet Joint Capsule

NCT07704853
View directory record Official record
Conditions
Neck Pain Musculoskeletal
Interventions
Long axis trust manipulation C5-C6
Other
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 35 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)

NCT00580294
View directory record Official record
Conditions
Pain
Interventions
Oxymorphone
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Sep 30, 2026, 12:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time

NCT00042276
View directory record Official record
Conditions
Neck Pain
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Sep 30, 2026, 12:53 AM EDT
Withdrawn Phase 2 Interventional

Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain

NCT00795106
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Capsaicin, Placebo
Drug
Lead sponsor
Stamford Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Sep 30, 2026, 12:53 AM EDT
Terminated No phase listed Observational

Bone Graft Materials Observational Registry

NCT00974623
View directory record Official record
Conditions
Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis, Spinal Deformity, Cervical Myelopathy, Failed Back Surgery Syndrome, Spinal Cord Neoplasms
Interventions
Bone graft substitute, autograft or allograft
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
12
States / cities
San Francisco, California • Atlanta, Georgia • Carrollton, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Sep 30, 2026, 12:53 AM EDT
Not listed No phase listed Observational

Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis

NCT04222244
View directory record Official record
Conditions
Headache
Interventions
No intervention will be administered. We are only performing tests and measures.
Other
Lead sponsor
Des Moines University
Other
Eligibility
18 Years to 65 Years
Enrollment
82 participants
Timeline
2020 – 2022
U.S. locations
7
States / cities
Hartford, Connecticut • Des Moines, Iowa • Lafayette, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2020 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time

NCT01223365
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydrocodone ER
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
54
States / cities
Mobile, Alabama • Anaheim, California • Beverly Hills, California + 46 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Sep 30, 2026, 12:53 AM EDT
Not yet recruiting Not applicable Interventional

Musical Mindfulness for Pain in the ED Waiting Room

NCT07391891
View directory record Official record
Conditions
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
Interventions
Music intervention
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgeons Can Avoid Lasting Pain Through Exercise Literacy

NCT05175443
View directory record Official record
Conditions
Neck Pain, Shoulder Pain
Interventions
Exercise
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
18 Years to 99 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Sep 30, 2026, 12:53 AM EDT
Terminated No phase listed Observational

Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients

NCT02761928
View directory record Official record
Conditions
Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical, Benign Hypermobility Syndrome
Interventions
Beighton score for hypermobility
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 30, 2026, 12:53 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders

NCT06143228
View directory record Official record
Conditions
Whiplash Injury of Cervical Spine, Muscle Weakness
Interventions
Not listed
Lead sponsor
D'Youville College
Other
Eligibility
19 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Tallahassee, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Sep 30, 2026, 12:53 AM EDT
Not listed No phase listed Observational

Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management

NCT02485795
View directory record Official record
Conditions
Pain, Chronic Pain, Back Pain, Nociceptive Pain, Neuropathic Pain, Musculoskeletal Pain, Neck Pain, Pain, Intractable
Interventions
Observational
Other
Lead sponsor
Proove Bioscience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
31
States / cities
Prescott, Arizona • Heber Springs, Arkansas • Beverly Hills, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Sep 30, 2026, 12:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution

NCT04444102
View directory record Official record
Conditions
Inflammation, Fascia; Inflammation, Musculoskeletal Pain, Lower Back Pain, Neck Pain
Interventions
Yoga-based stretching
Procedure
Lead sponsor
Harvard University Faculty of Medicine
Other
Eligibility
40 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional

Association Between Conditioned Pain Modulation and the 4-week Response to Spinal Mobilization in Adults With Chronic Neck Pain

NCT07194603
View directory record Official record
Conditions
Neck Pain Musculoskeletal, Chronic
Interventions
Spinal mobilization (SM) of the neck
Procedure
Lead sponsor
Azusa Pacific University
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Azusa, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Phase 2 Interventional

Development of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation

NCT00835302
View directory record Official record
Conditions
Shoulder Pain
Interventions
Cervicothoracic manipulation
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
6
States / cities
Aurora, Colorado • Boulder, Colorado • Greenwood Village, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 30, 2026, 12:53 AM EDT
Completed No phase listed Observational

Central Sensitization in Patients Seeking Outpatient Physical Therapy Services

NCT05467592
View directory record Official record
Conditions
Low Back Pain, Knee Osteoarthritis, Neck Pain
Interventions
Standard Physical Therapy care
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
77 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Shawnee Mission, Kansas
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 30, 2026, 12:53 AM EDT
Completed Not applicable Interventional Results available

The Effect of Low Level Laser Therapy on Neck and Shoulder Pain

NCT03941912
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Erchonia EVRL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Largo, Florida • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Sep 30, 2026, 12:53 AM EDT