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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Musculoskeletal Sprain Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Strength Training on Musculoskeletal Overuse Injuries in Female Runners

NCT03080246
View directory record Official record
Conditions
Overuse Injury
Interventions
Strength Training Exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Question Prompt List for Common Hand Conditions

NCT03868449
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Trigger Finger, Trigger Thumb, Dupuytren Contracture, Ganglion Cysts
Interventions
Question Prompt List, 3 questions
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Sep 7, 2026, 4:27 PM EDT
Enrolling by invitation Phase 2 Interventional

124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome

NCT06907849
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS), Cardiac Amyloidosis
Interventions
124I-evuzamitide
Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation

NCT03663361
View directory record Official record
Conditions
Ankle Sprains
Interventions
SMART Intervention, Standard of Care Intervention
Other
Lead sponsor
Phillip Gribble
Other
Eligibility
18 Years to 44 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nylon Versus Chromic Gut Sutures for Minor Hand Surgery

NCT03407820
View directory record Official record
Conditions
All Minor Hand Surgery Including, Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts, De Quervain Syndrome, Dupuytren Contracture
Interventions
Absorbable Chromic gut sutures, Non-absorbable Nylon sutures
Procedure
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department

NCT03571737
View directory record Official record
Conditions
Acute Musculoskeletal Disease, Sprains, Sprains and Strains, Injuries, Emergencies, Trauma, Acute Pain
Interventions
Ibuprofen, Lidocaine Patch 4%
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2024 · Synced Sep 7, 2026, 4:27 PM EDT
Completed No phase listed Observational

AMPED Outcomes Registry of Post-ED Pain Management

NCT01626235
View directory record Official record
Conditions
Soft Tissue Injuries, Gouty Arthritis, Fractures, Ureteral Colic, Dysmenorrhea
Interventions
Not listed
Lead sponsor
Radnor Registry Research, Inc
Industry
Eligibility
18 Years and older
Enrollment
843 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
11
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Jackson, Mississippi + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Sep 7, 2026, 4:27 PM EDT
Active, not recruiting Not applicable Interventional

Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness

NCT05038709
View directory record Official record
Conditions
Hip Osteoarthritis, Hip Injuries, Hip Sprain, Hip Strain
Interventions
The Pink Pad Hip Kit
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 88 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 7, 2026, 4:27 PM EDT
Suspended Not applicable Interventional

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

NCT01693094
View directory record Official record
Conditions
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures, Trigger Finger
Interventions
Decision Aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 7, 2026, 4:27 PM EDT
Terminated Phase 4 Interventional

Platelet-rich Plasma, Corticosteroid, or Lidocaine for Acromioclavicular Joint Pain

NCT05161468
View directory record Official record
Conditions
Acromioclavicular Sprain
Interventions
Lidocaine injection, Corticosteroid Injection, Protein Rich Plasma(PRP) Injection
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 7, 2026, 4:27 PM EDT
Recruiting No phase listed Observational

The KinematX Midcarpal Total Wrist Arthroplasty Registry

NCT05719935
View directory record Official record
Conditions
Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS), Kienbock's Disease of Adults, Radial Malunion, Ulnar Translocation, Post Traumatic Arthritis, Inflammatory Arthritis, Osteoarthritis, Scaphoid Non-union Advanced Collapse (SNAC)
Interventions
KinematX total wrist arthroplasty system
Device
Lead sponsor
Extremity Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
4
States / cities
Loma Linda, California • Tampa, Florida • Indianapolis, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Phase 3 Interventional

Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury

NCT00765700
View directory record Official record
Conditions
Sprain, Strain, Acute Soft Tissue Injury
Interventions
Topical Ketoprofen 10% Cream, Topical Placebo Cream
Drug
Lead sponsor
Imprimis Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2013 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional Results available

Non-invasive CTS Device Clinical Trial

NCT03498287
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Study Device, Sham Device
Device
Lead sponsor
Pressure Profile Systems, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Mission Viejo, California • Torrance, California • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Brace to Prevent Hand and Arm Injuries

NCT00074893
View directory record Official record
Conditions
Cumulative Trauma Disorders, Carpal Tunnel Syndrome
Interventions
piezoelectric wrist brace
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
21 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2006 · Synced Sep 7, 2026, 4:27 PM EDT
Withdrawn Not applicable Interventional

The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains

NCT05596162
View directory record Official record
Conditions
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
Interventions
Blood Flow Restriction Therapy, Standard Physical Therapy
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 7, 2026, 4:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Work and Health Disparities Among Rural Women

NCT00042419
View directory record Official record
Conditions
Tendonitis, Carpal Tunnel Syndrome, Cumulative Trauma Disorders, Overuse Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 3, 2006 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery

NCT04424810
View directory record Official record
Conditions
Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient, Pain
Interventions
High-quality, physician created video, Standard of care
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 7, 2026, 4:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ergonomic Protocol for Competitive E-Sport Athletes

NCT06781580
View directory record Official record
Conditions
No Disease or Condition is Being Studied
Interventions
Esports Ergonomic Protocol
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Sep 7, 2026, 4:27 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Clinical Outcomes of Autologous Bone Marrow Aspirate Concentrate Injections for Musculoskeletal Conditions

NCT02981394
View directory record Official record
Conditions
Musculoskeletal Pain, Osteoarthritis, Tendinopathy, Sprains Strain
Interventions
Bone Marrow Aspirate Concentrate Injection
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-surgical Intervention for Carpal Tunnel Syndrome

NCT03360344
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Susceptibility to
Interventions
Kinesio 12 inch Tape, Kinesio 4 inch Tape, Cock up Splint and Lumbrical exercises
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 99 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 7, 2026, 4:27 PM EDT
Withdrawn No phase listed Observational

Alternatives to Hand Therapy for Hand Surgery Patients

NCT03779958
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts, Distal Radius Fracture, Finger Fracture, De Quervain Syndrome
Interventions
Mobile App
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Resident Posture Biofeedback Study

NCT06564519
View directory record Official record
Conditions
Postural; Strain, Healthy
Interventions
Posture Biofeedback Device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 7, 2026, 4:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Musculoskeletal Health of the Upper Extremity in Emerging Health Professionals

NCT02587897
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Academic Coursework, Work-Related Hand Activities
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
3
States / cities
Loma Linda, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 7, 2026, 4:27 PM EDT
Completed Not applicable Interventional

Pain Management Following Musculoskeletal Injury

NCT01689675
View directory record Official record
Conditions
Musculoskeletal Strain, Musculoskeletal Sprain, Injury of Musculoskeletal System
Interventions
Computer based pain management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 7, 2026, 4:27 PM EDT