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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:44 AM EST

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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Myofascial Pain Syndromes Clear all

Conditions: Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interventions: Bupivacaine; Drug
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 2
States / cities: Akron, Ohio • Cleveland, Ohio

Conditions: Cervicobrachial Neuralgia, Myofascial Pain Syndromes
Interventions: Botulinum toxin serotype A; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2003
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Temporomandibular Joint Dysfunction Syndrome, Burning Mouth Syndrome
Interventions: nalbuphine plus naloxone, nalbuphine plus placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Temporomandibular Joint Syndrome
Interventions: 3D Analysis Group, Manual Analysis Cohort; Device · Other
Lead sponsor: Dr. Dean Reeves Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Gainesville, Texas

Conditions: Myofascial Pain Syndrome, Healthy
Interventions: Ultrasound imaging, Bioimpedance spectroscopy, Electromyography, Physical examination; Diagnostic Test
Lead sponsor: George Mason University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Postmastectomy Lymphedema Syndrome, Pain, Shoulder Mobility Impairment, Breast Surgery
Interventions: Myofascial Massage Therapy, Global Relaxation Massage; Other
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 21 Years to 79 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: Ultrasound Sonicator 740; Device
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Myofascial Pain Syndromes
Interventions: Heated lidocaine/tetracaine patch; Drug
Lead sponsor: ZARS Pharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Temporomandibular Joint Syndrome, Myofascial Pain Dysfunction Syndrome, Orofacial Pain
Interventions: Cognitive-Behavioral treatment, Attention and lifestyle counseling; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Myofascial Pain, Trigger Point Pain, Myofascial
Interventions: Ultrasound, Electrical impedance myography, Excitability testing; Diagnostic Test
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Refractory Cervicothoracic Myofascial Pain Syndrome (CMPS), Cervical Dystonia
Interventions: Botulinum Toxin Type A; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: ultrasound; Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older · Female only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Myofascial Pain Syndromes
Interventions: The GRID foam roll; Device
Lead sponsor: California State University, Dominguez Hills; Other
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Carson, California

Conditions: Masticatory Myofascial Pain Syndrome
Interventions: Onabotulinumtoxin A, Placebo; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: New York, New York

Conditions: Opiate Addiction, Refractory Pain
Interventions: buprenorphine/naloxone; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Chronic Pelvic Pain, Interstitial Cystitis, Post Traumatic Stress Disorder, Fibromyalgia, Irritable Bowel Syndrome
Interventions: tDCS; Procedure
Lead sponsor: Summa Health System; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Myofascial Trigger Point Pain, Myofacial Pain
Interventions: Trigger point injection with 1% lidocaine, Lidocaine patch 5%; Procedure · Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Orange, California

Conditions: Trigger Point Pain, Myofascial
Interventions: Positional release therapy, Therapeutic Massage; Other
Lead sponsor: Brigham Young University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Provo, Utah

Conditions: Fibromyalgia, Myofascial Pain Syndrome, Muscular Diseases, Musculoskeletal Disease, Rheumatic Diseases
Interventions: Fibromyalgia Integrative Training for Teens, Cognitive Behavioral Therapy, Graded Aerobic Exercise; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 12 Years to 18 Years
Enrollment: 389 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 6
States / cities: Hartford, Connecticut • Indianapolis, Indiana • Boston, Massachusetts + 3 more

Conditions: Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome, Myalgia of Pelvic Floor
Interventions: SoLá therapy, Pelvic floor physical therapy; Device · Other
Lead sponsor: Orlando VA Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Trigger Point Pain, Myofascial
Interventions: Dry Needling, Sham Dry Needlling; Other
Lead sponsor: Regis University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Myofascial Pain Syndrome
Interventions: OMT; Procedure
Lead sponsor: AtlantiCare Regional Medical Center; Other
Eligibility: 25 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Atlantic City, New Jersey

Conditions: Myofascial Pain Syndrome
Interventions: Normal Saline, Lidocaine Hydrochloride, Triamcinolone acetonide; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Temporomandibular Disorders
Interventions: Erenumab-Aooe 70 MG in 1 mL Prefilled Syringe, Placebo; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study

Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome

Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain

Temporomandibular Joint (TMJ) Positioning Accuracy and Efficiency Using a Dental Compass.

Imaging Biomarkers for Myofascial Pain

Massage for Post Breast Surgery

Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial

Study Evaluating Heated Lidocaine/Tetracaine Patch in Patients With Pain Associated With Myofascial Trigger Points

Brief Treatment for Temporomandibular Pain

Evaluation of a Novel Class of Objective Myofascial Pain Assessments

Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain

Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia

Does Self-myofascial Release With a Foam Roll Change Pressure Pain Thresholds in Lower Extremity Muscles

MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain

Buprenorphine as a Treatment in Opiate Dependent Pain Patients

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

Trigger Point Injections Versus Lidocaine Patch for Myofascial Pain in the Emergency Department

Positional Release Therapy and Therapeutic Massage Reduce Muscle Trigger and Tender Points

Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia

Photobiomodulation for Myofascial Pelvic Pain

The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points

OMTrigger Inject- Treating Trigger Points: Comparing Muscle Energy Technique vs. Lidocaine Needling Technique

Using Saline for Myofascial Pain Syndromes (USAMPS)

Erenumab-aooe for Temporomandibular Disorders Management: TMD Cgrp Antibody RElief (TMD CARE)