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ClinicalTrials.gov public records Last synced Jul 22, 2026, 6:07 AM EDT

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Showing 1–24 of 76 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Recruiting No phase listed Observational Accepts healthy volunteers

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

NCT02576483
Conditions
Nearsightedness, Farsightedness, Astigmatism
Interventions
Questionnaire (QoV questionnaire)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 62 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dispensing Evaluation of Investigational Contact Lenses

NCT02625220
Conditions
Myopia; Astigmatism
Interventions
Prototype toric lens senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
12
States / cities
Jacksonville, Florida • Pembroke Pines, Florida • Winter Park, Florida + 9 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison of LASIK Outcomes Using Two Femtosecond Lasers

NCT03063164
Conditions
Myopia, Astigmatism
Interventions
Intralase IFS150, Visumax
Device
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Myopia, Myopic Astigmatism
Interventions
Technolas® TENEO 317 Model 2
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
10
States / cities
Newport Beach, California • Blaine, Minnesota • Bloomington, Minnesota + 7 more
Conditions
Myopia, Astigmatism
Interventions
comfilcon A Toric
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Conditions
Myopia, Myopic Astigmatism
Interventions
EVO/EVO+ Visian ICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
14
States / cities
Phoenix, Arizona • Honolulu, Hawaii • Indianapolis, Indiana + 11 more
Not listed Phase 4 Interventional Accepts healthy volunteers

Multi Laser Platform Comparison Study for LASIK

NCT00770094
Conditions
Myopia, Astigmatism
Interventions
Excimer Lasers, Excimer Laser for the LASIK procedure, Excimer Laser for LASIK
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia • Edina, Minnesota • McLean, Virginia
Conditions
Myopia, Astigmatism, Refractive Error
Interventions
OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Myopia, Myopic Astigmatism
Interventions
WFG PRK, WFG LASIK, WFO PRK, WFO LASIK
Procedure
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
21 Years to 55 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Completed No phase listed Observational Accepts healthy volunteers

Wavefront-guided Versus Wavefront-optimized LASIK for Nearsightedness

NCT01138189
Conditions
Myopia, Astigmatism
Interventions
Wavefront-guided LASIK, Wavefront-optimized LASIK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Stanford, California
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Active, not recruiting Not applicable Interventional

LASIK iDesign vs SMILE

NCT07126756
Conditions
Myopia, Astigmatism
Interventions
STAR S4 IR Excimer Laser System, VisuMax 400 Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Conditions
Hyperopia, Myopia, Astigmatism
Interventions
LASIK and PRK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Stanford, California
Conditions
Myopia, Astigmatism
Interventions
Visibly Vision Test
Device
Lead sponsor
Visibly
Industry
Eligibility
22 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Harlingen, Texas
Completed Not applicable Interventional Results available

Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses

NCT02185105
Conditions
Myopia, Astigmatism
Interventions
comfilcon A MTO, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Myopia, Astigmatism
Interventions
VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
Procedure
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
7
States / cities
Fayetteville, Arkansas • Rowland Heights, California • Leawood, Kansas + 4 more
Conditions
Laser in Situ Keratomileusis
Interventions
LASIK
Procedure
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
21 Years to 84 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
5
States / cities
Stanford, California • Indianapolis, Indiana • Overland Park, Kansas + 2 more
Conditions
Myopia
Interventions
Photorefractive Keratectomy (PRK)
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
11
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 8 more
Conditions
Refractive Errors
Interventions
Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
San Diego, California • Jacksonville, Florida • Orlando, Florida + 9 more
Conditions
Myopia, Astigmatism
Interventions
Contoura LASIK with Phorcides planning strategy, Contoura LASIK with manifest refraction planning strategy
Device
Lead sponsor
Bismarck Lasik
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Completed Not applicable Interventional Accepts healthy volunteers

APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism

NCT04883099
Conditions
Presbyopia, Myopia, Hyperopia, Astigmatism
Interventions
APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
San Diego, California • Orlando, Florida • Lexington, Kentucky + 3 more
Completed Not applicable Interventional Results available

STAAR Visian Toric ICL Post-Approval Study

NCT04516772
Conditions
Myopic Astigmatism
Interventions
Visian TICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Honolulu, Hawaii • Indianapolis, Indiana • Bowie, Maryland + 5 more
Completed Not applicable Interventional Results available

Post-Market Evaluation of the EVO ICL

NCT05538754
Conditions
Myopia, Myopic Astigmatism
Interventions
EVO ICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Honolulu, Hawaii • Overland Park, Kansas • Omaha, Nebraska + 5 more