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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Myopic Astigmatism Clear all
Completed Not applicable Interventional Results available

STAAR Visian Toric ICL Post-Approval Study

NCT04516772
View directory record Official record
Conditions
Myopic Astigmatism
Interventions
Visian TICL
Device
Lead sponsor
Staar Surgical Company
Industry
Eligibility
21 Years to 45 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Honolulu, Hawaii • Indianapolis, Indiana • Bowie, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Clinical Investigation of the Vision-R800 Device.

NCT04208750
View directory record Official record
Conditions
Myopia, Hyperopia, Astigmatism, Presbyopia
Interventions
Vision R-800 Phoropter, Standard Phoropter
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

NCT05483127
View directory record Official record
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Jul 22, 2026, 2:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quality of Vision and Quality of Life With LASIK

NCT02161263
View directory record Official record
Conditions
Myopia, Astigmatism, Quality of Lifte
Interventions
Patient Quality of Life andVision after LASIK Surgery
Other
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism

NCT04883099
View directory record Official record
Conditions
Presbyopia, Myopia, Hyperopia, Astigmatism
Interventions
APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
San Diego, California • Orlando, Florida • Lexington, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jul 22, 2026, 2:18 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

The Role of Psychosocial and Other Quality of Life Parameters in Evaluating Functional Changes Prior to and Following Laser In-situ Keratomileusis (LASIK)Changes Laser In-situ Keratomileusis (LASIK)

NCT00344604
View directory record Official record
Conditions
Keratomileusis, Laser In Situ
Interventions
Role of psychosocial and quality of life parameters prior to and following LASIK.
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Jul 22, 2026, 2:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness

NCT01365728
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
LASIK with the iFS femtosecond laser
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses

NCT06165627
View directory record Official record
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Jul 22, 2026, 2:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Refractive Accuracy of "2WIN" and Portable Autorefractors

NCT04249505
View directory record Official record
Conditions
Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment, Hyperopia of Both Eyes
Interventions
"2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
Device
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
6 Months to 95 Years
Enrollment
708 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison of LASIK Outcomes Using Two Femtosecond Lasers

NCT03063164
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Intralase IFS150, Visumax
Device
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK

NCT00821236
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Excimer Laser, AMO/VISX CustomVue™, LADARVision 4000 excimer laser
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Overland Park, Kansas • Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses

NCT02423109
View directory record Official record
Conditions
Myopia, Hyperopia, Astigmatism
Interventions
fanfilcon A, enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
17 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
View directory record Official record
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Jul 22, 2026, 2:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure

NCT05740293
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
Procedure
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
7
States / cities
Fayetteville, Arkansas • Rowland Heights, California • Leawood, Kansas + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional

SMILE vs. LASIK Using Contoura With Phorcides

NCT05844397
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
WaveLight EX500 Excimer Laser System, VisuMax Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers

NCT01211535
View directory record Official record
Conditions
Myopia, Astigmatism, Refractive Error
Interventions
OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 11, 2012 · Synced Jul 22, 2026, 2:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery

NCT07078799
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 22, 2026, 2:18 PM EDT
Recruiting Not applicable Interventional

Contoura With Phorcides Compared to Wavefront Optimized LASIK

NCT05486546
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura with Phorcides, WaveLight Wavefront Optimized
Procedure · Device
Lead sponsor
Daniel Terveen
Other
Eligibility
21 Years to 38 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap

NCT04219891
View directory record Official record
Conditions
Myopia
Interventions
WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
9
States / cities
San Diego, California • Indianapolis, Indiana • Chevy Chase, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser

NCT02430428
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Carl Zeiss Meditec VisuMax Femtosecond Laser
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Greenwood Village, Colorado • Leawood, Kansas • Sioux Falls, South Dakota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Jul 22, 2026, 2:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism

NCT07201298
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK, Topography Guided LASIK
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 22, 2026, 2:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

NCT04072289
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Visumax spherocylindrical treatment
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Jul 22, 2026, 2:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia

NCT01140594
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Photorefractive keratectomy, Laser in-situ keratomileusis
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2022 · Synced Jul 22, 2026, 2:18 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluation of Alcon Ladarvision Wavefront-Guided PRK

NCT00412295
View directory record Official record
Conditions
Myopia
Interventions
Alcon Ladarvision (Wavefront-guided PRK)
Device
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
U.S. locations
2
States / cities
San Diego, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Jul 22, 2026, 2:18 PM EDT