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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Myringotomy Clear all
Terminated No phase listed Observational

Eustachian Tube Function and Myringoplasty/Tympanoplasty

NCT01766856
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Eustachian tube function testing
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
3 Years to 16 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Sep 12, 2026, 2:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion

NCT02134327
View directory record Official record
Conditions
Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
Interventions
Combination of Dexmedetomidine with Midazolam
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Months to 4 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Not applicable Interventional Results available

inVENT-In-Office Study

NCT01324271
View directory record Official record
Conditions
Otitis Media
Interventions
Acclarent Tympanostomy Tube Delivery system (TTDS)
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
6 Months and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 12, 2026, 2:59 PM EDT
Not yet recruiting Phase 4 Interventional

Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy

NCT07276906
View directory record Official record
Conditions
Postoperative Pain
Interventions
Fentanyl, Ketorolac, Nerve of Arnold Block, Sham Intramuscular Injection, Sham Nerve of Arnold Block, Dexmedetomidine, Bupivacaine
Drug · Procedure
Lead sponsor
University of South Alabama
Other
Eligibility
6 Months to 6 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 12, 2026, 2:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Topical Treatment of Acute Otitis Media Through Tympanostomy Tubes (AOMT) and Its Effect on Microbial Flora

NCT01027494
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 4 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Dexmedetomidine vs Fentanyl for BMT

NCT00654329
View directory record Official record
Conditions
Otitis
Interventions
Saline, Fentanyl, Dexmedetomidine
Drug
Lead sponsor
Children's National Research Institute
Other
Eligibility
6 Months to 6 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2011 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement

NCT01188551
View directory record Official record
Conditions
Chronic Otitis Media
Interventions
Dexmedetomidine, Fentanyl, Midazolam
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Sep 12, 2026, 2:59 PM EDT
Completed No phase listed Observational Results available

Study of the Hummingbird TTS™ Tympanostomy Tube System

NCT03503591
View directory record Official record
Conditions
Otitis Media
Interventions
Hummingbird Tympanostomy Tube System
Device
Lead sponsor
Preceptis Medical, Inc.
Industry
Eligibility
6 Months to 5 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • Saint Cloud, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 12, 2026, 2:59 PM EDT
Withdrawn Not applicable Interventional

Refractory Eustachian Tube Dysfunction: Are the Symptoms Related to Endolymphatic Hydrops

NCT01661777
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Endolymphatic Hydrops
Interventions
Nasal steroid, Myringotomy tube placement, Diuretic, Antihistamine, Low salt diet
Drug · Procedure · Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 28, 2014 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Not applicable Interventional

Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement

NCT02383004
View directory record Official record
Conditions
Delirium, Psychomotor Agitation
Interventions
Acupuncture
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Year to 6 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 17, 2017 · Synced Sep 12, 2026, 2:59 PM EDT
Not yet recruiting Not applicable Interventional

Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media

NCT07639775
View directory record Official record
Conditions
Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children, Otitis Media Chronic, Otitis Media in Children, Tympanostomy Tube Insertion, Osteopathic Manipulative Treatment (OMT)
Interventions
Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
Other
Lead sponsor
Sarah Vidal
Other
Eligibility
6 Months to 6 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 12, 2026, 2:59 PM EDT
Not listed Phase 4 Interventional

Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children

NCT02653742
View directory record Official record
Conditions
Pain, Postoperative, Otitis Media
Interventions
Ketorolac, Fentanyl
Drug
Lead sponsor
Anica Crnkovic
Other
Eligibility
8 Months to 7 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2021 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 3 Interventional Results available

OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement

NCT01949155
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
OTO-201, Sham
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 4 Interventional Results available

Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy

NCT01244126
View directory record Official record
Conditions
Otitis Media
Interventions
Intranasal fentanyl, morphine IM, IV morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Months to 6 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11

NCT00365092
View directory record Official record
Conditions
Otitis Media, Middle Ear Effusion
Interventions
Insertion of tympanostomy tubes
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
0 Years to 61 Days
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2006 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Not applicable Interventional Results available

Clinical Study of the Tympanostomy Tube Delivery System

NCT00939796
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
Acclarent Tympanostomy Tube Delivery System
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
Biloxi, Mississippi • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 3 Interventional Results available

In-Office Tympanostomy Tube Placement in Children (OTTER)

NCT03323736
View directory record Official record
Conditions
OME - Otitis Media With Effusion, AOM - Acute Otitis Media
Interventions
Iontophoresis & tube placement, Tube placement
Combination Product · Device
Lead sponsor
Tusker Medical
Industry
Eligibility
6 Months to 12 Years
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
18
States / cities
Carlsbad, California • Roseville, California • San Jose, California + 14 more
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 12, 2026, 2:59 PM EDT
Completed No phase listed Observational

Clinical Evaluation of the OtoSight

NCT03890107
View directory record Official record
Conditions
Otitis Media
Interventions
OtoSight Middle Ear Scope
Device
Lead sponsor
PhotoniCare, Inc.
Industry
Eligibility
Up to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 12, 2026, 2:59 PM EDT
Completed No phase listed Observational

Middle Ear Pressure Disregulation After Tympanostomy Tube Insertion

NCT00393900
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
3 Years to 6 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Not applicable Interventional Results available

In-Office Study of the Hummingbird® in Children 6 Months-21 Years Old

NCT03544138
View directory record Official record
Conditions
Ear Infection, Otitis Media
Interventions
Hummingbird Tympanostomy Tube System (H-TTS)
Device
Lead sponsor
Preceptis Medical, Inc.
Industry
Eligibility
6 Months to 21 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
7
States / cities
Beverly Hills, California • Orlando, Florida • Bloomington, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Sep 12, 2026, 2:59 PM EDT
Recruiting Not applicable Interventional

CLIKX® Tympanostomy Tube Delivery System for the Placement of Tympanostomy Tubes

NCT07625657
View directory record Official record
Conditions
Otitis Media, Otitis Media Chronic, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media in Children
Interventions
CLiKX® Tympanostomy Tube Delivery System
Device
Lead sponsor
ClinQure, Inc.
Network
Eligibility
6 Months and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Louisville, Kentucky • Mesquite, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 1 Interventional Results available

Pediatric Pharmacokinetic (PK) Study of EXE844 Otic Suspension in Otitis Media at the Time of Tympanostomy Tube Insertion (OMTT)

NCT02539654
View directory record Official record
Conditions
Otitis Media With Effusion in Children, Otitis Media Recurrent
Interventions
EXE844 Sterile Otic Suspension, 0.3%, Tympanostomy Tube Insertion
Drug · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 12 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 1 Interventional

OTO-201 for Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement

NCT01755286
View directory record Official record
Conditions
Bilateral Middle Ear Effusion Requiring Tympanostomy Tube Placement
Interventions
OTO-201, Placebo, Sham
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 12 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 12, 2026, 2:59 PM EDT
Completed Phase 2 Interventional Results available

Dose Ranging Study of OTO-201 in AOMT

NCT02719158
View directory record Official record
Conditions
Acute Otitis Media, AOMT
Interventions
6 mg ciprofloxacin, 12 mg ciprofloxacin, Sham
Drug · Other
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 12, 2026, 2:59 PM EDT