Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 6:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 206 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: NAC Clear all

Conditions: Anosmia, Head Trauma
Interventions: N Acetyl Cysteine, Placebo oral capsule; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
Interventions: N-acetylcysteine, Placebo, Cognitive behavioral therapy; Drug · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Charleston, South Carolina

Conditions: Creatinine Clearance
Interventions: Acetylcysteine; Drug
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 18 Years to 79 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2006
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Bipolar Disorder
Interventions: Aspirin, N-acetyl-cysteine (NAC), Sugar Pill; Drug · Dietary Supplement
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Chronic Bronchitis
Interventions: Oral N-acetycystein (NAC); Drug
Lead sponsor: Wake Forest University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2000
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Mood Disturbance, Mood Disorders, Natural Supplements, Alternative Treatment
Interventions: Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 5 Years to 17 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cannabis Dependence
Interventions: N-Acetylcysteine, placebo, Contingency Management; Drug · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 13 Years to 21 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation, Chorioamnionitis
Interventions: amniocentesis, N-acetylcysteine or placebo; Procedure · Drug
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 2
States / cities: New Haven, Connecticut • Columbus, Ohio

Conditions: Covid-19
Interventions: N-acetylcysteine, Peripheral Blood; Drug · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Bipolar Disorder, Alcohol Use Disorder
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Acetaminophen Toxicity
Interventions: Not listed
Lead sponsor: Akron Children's Hospital; Other
Eligibility: Not listed
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Neurofibromatosis 1
Interventions: N-acetylcysteine (NAC), Placebo; Drug · Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 8 Years to 16 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Pathologic Skin Picking, Neurotic Excoriation, Psychogenic Excoriation, Dermatillomania
Interventions: N-Acetyl Cysteine, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 64 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cardiovascular Disease, Cigarette Smoking
Interventions: Subject's usual brand (UB) tobacco product; Other
Lead sponsor: R.J. Reynolds Tobacco Company; Industry
Eligibility: 26 Years to 49 Years · Male only
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Cognitive Dysfunction
Interventions: N-acetylcysteine and ketamine, placebo and ketamine; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Alcohol Consumption, Alcohol, Hangover Symptoms, NAC, Veisalgia
Interventions: Supplement, Placebo; Dietary Supplement
Lead sponsor: Medical Life Care Planners, LLC; Other
Eligibility: 21 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Myeloproliferative Neoplasm, MPN, Essential Thrombocythemia, Polycythemia Vera, Myelofibrosis
Interventions: N-Acetylcysteine; Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Irvine, California • Orange, California

Conditions: Ameliorating Oxidative Stress in Type 1 Diabetes
Interventions: N-acetyl cysteine, omega 6 Fish oil ( PUFA), Placebo; Drug · Dietary Supplement
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Breast Lift
Interventions: InModeRF; Device
Lead sponsor: InMode MD Ltd.; Industry
Eligibility: 21 Years to 60 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Asthma, COPD
Interventions: n-acetylcystine (NAC)+ albuterol, AeroEclipse-VersaPAP System; Drug · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Mild Cognitive Impairment
Interventions: Not listed
Lead sponsor: Pamlab, Inc.; Industry
Eligibility: 55 Years to 89 Years
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Gaucher Disease Type 1
Interventions: N-acetylcysteine; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2025
U.S. locations: 2
States / cities: Minneapolis, Minnesota • New York, New York

Conditions: Nephropathy
Interventions: Oral N-Acetylcysteine, Sodium Bicarbonate; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Infantile Neronal Ceroid Lipofuscinosis
Interventions: Cystagon; Drug
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 6 Months to 3 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2013
U.S. locations: 1
States / cities: Bethesda, Maryland

Search by objective public record fields.

NAC for Head Trauma-induced Anosmia

NAC for Treating Comorbid PTSD and SUD

Role of Acetylcysteine in Creatinine Clearance

N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder

Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic Bronchitis

A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth

A Trial of N-Acetylcysteine (an Over-the-Counter Medicine) in Adolescents Who Smoke Marijuana

N-acetylcysteine in Intra-amniotic Infection/Inflammation

A Study of N-acetylcysteine in Patients With COVID-19 Infection

N-Acetylcysteine for Bipolar and Alcohol Use Disorders

Treatment of Acetaminophen Toxicity With N-acetylcysteine

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

N-Acetyl Cysteine in Pathologic Skin Picking

Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers

N-acetylcysteine and NMDA Antagonist Interactions

Rapid BAC Reduction with Nutraceutical Blend Study

An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

Antioxidant Use in Diabetes to Reduce Oxidative Stress

Clinical Evaluation of RFAL of Breast Envelope and NAC Position

The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)

A Retrospective Analysis of Cerefolin NAC® in Cognitively Impaired Patients

Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)

A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate

Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis