Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 6:49 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 206 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: NAC Clear all

Conditions: Covid19
Interventions: Famotidine, N-Acetyl cysteine; Drug
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Easley, South Carolina • Greenville, South Carolina • Greer, South Carolina

Conditions: Systemic Lupus Erythematosus
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 12
States / cities: Los Angeles, California • New Haven, Connecticut • Atlanta, Georgia + 8 more

Conditions: Trichotillomania, Hair Pulling
Interventions: N-Acetylcysteine, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 8 Years to 17 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Autistic Disorder
Interventions: N-Acetyl Cysteine; Drug
Lead sponsor: Stanford University; Other
Eligibility: 3 Years to 12 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Stanford, California

Conditions: Contrast Induced Nephropathy
Interventions: N-acetylcysteine; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypertrophic Cardiomyopathy
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Schizophrenia
Interventions: N-Acetylcysteine, Placebo; Dietary Supplement · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Breast Cancer, HER2-positive Breast Cancer, TNBC - Triple-Negative Breast Cancer, HER2-negative Breast Cancer, Invasive Breast Carcinoma
Interventions: NearWave monitoring; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Diabetic Nephropathy, Proteinuria, Oxidative Stress
Interventions: N-acetylcysteine placebo and silibin placebo, N-acetylcysteine active and silibin placebo, N-acetylcysteine placebo and silibin active, N-acetylcysteine active and silibin active, N-acetylcysteine active + high-dose silibin active; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 76 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Stage 0/1 Breast Cancer, Post Biopsy, Pre-surgery
Interventions: IV/oral n-acetylcysteine; Drug
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chorioamnionitis, Brain Injury
Interventions: N-acetylcysteine, Control; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 13 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcoholism
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Traumatic Brain Injury
Interventions: N-Acetyl cysteine; Drug
Lead sponsor: HonorHealth Research Institute; Other
Eligibility: 60 Years to 100 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Phoenix, Arizona

Conditions: Multiple Sclerosis
Interventions: N-acetyl Cysteine; Dietary Supplement
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Healthy
Interventions: OP-101; Drug
Lead sponsor: Orpheris, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Acetaminophen Overdose
Interventions: Acetadote EF (Ethylenediaminetetraacetic Acid (EDTA) - Free), Acetadote; Drug
Lead sponsor: Cumberland Pharmaceuticals; Industry
Eligibility: 12 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 14
States / cities: Phoenix, Arizona • Loma Linda, California • Orange, California + 11 more

Conditions: Schizophrenic Psychoses
Interventions: n-acetylcysteine, Placebo; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 35 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Nipple Sparing Mastectomy
Interventions: Nipple-Sparing Mastectomy; Device
Lead sponsor: Intuitive Surgical; Industry
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 6
States / cities: Jacksonville, Florida • Evanston, Illinois • Rochester, Minnesota + 3 more

Conditions: Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
Interventions: N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule, Functional magnetic resonance imaging (fMRI), Proton magnetic resonance spectroscopy (MRS) Imaging; Drug · Behavioral · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 2
States / cities: Charleston, South Carolina

Conditions: Kidney Failure
Interventions: N-Acetylcysteine; Drug
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parkinson Disease, Cerebrospinal Fluid
Interventions: N-Acetylcysteine, Lumbar Puncture, Fluoroscopy; Drug · Procedure · Radiation
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Parkinson's Disease, Gaucher's Disease
Interventions: N-acetylcysteine; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Nicotine Dependence
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cocaine Use Disorder, Opioid Use Disorder, Stimulant Use Disorder
Interventions: n-acetylcysteine, Hydromorphone, Placebo n-acetylcystine, Placebo hydromorphone; Drug
Lead sponsor: William Stoops; Other
Eligibility: 18 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Lexington, Kentucky

Search by objective public record fields.

Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19

Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine

N-Acetylcysteine for Pediatric Trichotillomania

An Open-Label Study of N-Acetyl Cysteine in Children With Autism

Safety Study Of N-Acetylcysteine For Prevention Of Contrast Induced Nephropathy In Patients w/Stage 3 Renal Failure

Hypertrophic Regression With N-Acetylcysteine in HCM

A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia

NearWave Optical Molecular Monitoring

N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy

Pilot Study of Anti-oxidant Supplementation With N-Acetyl Cysteine in Stage 0/I Breast Cancer

Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)

N-acetylcysteine in Alcohol Dependence

Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients

Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OP-101 After Intravenous Administration in Healthy Volunteers

Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection

N-Acetyl-Cysteine (NAC) in Early Phase Schizophrenia Spectrum Psychosis

Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy

Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)

Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery

Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease?

Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease

N-Acetylcysteine and Smoking Reduction

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)