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Showing 1–24 of 199 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nasal Breathing Clear all
Active, not recruiting No phase listed Observational

A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.

NCT06922955
View directory record Official record
Conditions
Nasal Airway Obstruction
Interventions
Not listed
Lead sponsor
Aerin Medical
Industry
Eligibility
22 Years to 85 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
35
States / cities
Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Phase 3 Interventional

Investigation of Potential Additive Inhibitory Effects on HPA-Axis of Ciclesonide Nasal Spray When Administered Concomitantly With Orally Inhaled Beclomethasone Dipropionate (HFA-BDP) in Patients With Perennial Allergic Rhinitis (PAR) (BY9010/M1-408)

NCT00659048
View directory record Official record
Conditions
Rhinitis, Allergic, Perennial
Interventions
Ciclesonide, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 60 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Sep 14, 2026, 4:03 AM EDT
Completed No phase listed Observational

Clinical Evaluation of QFlu Combo Test

NCT01506583
View directory record Official record
Conditions
Cough, Myalgia, Nasal Obstruction, Sore Throat, Headache, Fatigue, Fever
Interventions
Not listed
Lead sponsor
Cellex, Inc.
Industry
Eligibility
Not listed
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Birmingham, Alabama • Chicago, Illinois • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient

NCT03671837
View directory record Official record
Conditions
Apneic; Oxygenation
Interventions
Oxygen, Air
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Sep 14, 2026, 4:03 AM EDT
Completed No phase listed Observational Results available

Quality of Life Impact of Nasal Airway Treatment With Aerin Medical Device

NCT03290300
View directory record Official record
Conditions
Nasal Obstruction
Interventions
Vivaer Stylus
Device
Lead sponsor
Aerin Medical
Industry
Eligibility
22 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
8
States / cities
Fresno, California • Colorado Springs, Colorado • Oradell, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Phase 4 Interventional Results available

The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation

NCT02877485
View directory record Official record
Conditions
Nasal Obstruction
Interventions
Triamcinolone Acetonide, Ayr saline nasal mist
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 100 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Sep 14, 2026, 4:03 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Analysis of Impact on Nasal Obstruction by Commercially Available Internal Nasal Stents

NCT00683254
View directory record Official record
Conditions
Nasal Obstruction
Interventions
Not listed
Lead sponsor
Bethany L. Jones
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Sep 14, 2026, 4:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Trial Comparing Microdebrider-Assisted Inferior Turbinoplasty (MAIT) vs Submucous Resection (SMR)

NCT02695602
View directory record Official record
Conditions
Nasal Obstruction
Interventions
Microdebrider-Assisted Inferior Turbinoplasty (MAIT), Submucous Resection with non powered instrument
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of High-Flow Nasal Cannula on Swallow Function

NCT03590457
View directory record Official record
Conditions
Swallowing Disorder, Respiratory Insufficiency
Interventions
Airvo 2; High-Flow nasal cannula system
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Sep 14, 2026, 4:03 AM EDT
Not listed Not applicable Interventional

A Pilot Study Comparing Oxygen Delivery Via Helmet Interface Versus High Flow Nasal Cannula

NCT04035460
View directory record Official record
Conditions
Hypoxemic Respiratory Failure
Interventions
Helmet, High Flow Nasal Oxygen
Device
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Sep 14, 2026, 4:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ozone Exposure and Dose Delivered to Human Lungs

NCT00013780
View directory record Official record
Conditions
Lung Disease
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2003
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2006 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment

NCT01939938
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Nasal and Oronasal PAP Mask
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Sep 14, 2026, 4:03 AM EDT
Terminated Not applicable Interventional Results available

High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation

NCT01270581
View directory record Official record
Conditions
Transient Tachypnea of the Newborn
Interventions
High Flow Nasal Cannula, Bubble Nasal CPAP
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional

Turbinate Cauterization in Pediatric Patients With Nasal Obstruction

NCT01695967
View directory record Official record
Conditions
Sleep Apnea, Nasal Obstruction
Interventions
turbinate cauterization
Procedure
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
3 Years to 16 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Steady State Kinetics of l-Methamphetamine and Validation of Sensitivity of Dose Estimation

NCT00829634
View directory record Official record
Conditions
Nasal Congestion
Interventions
l-methamphetamine, d-methamphetamine
Drug
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Phase 3 Interventional

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

NCT00665977
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 6, 2010 · Synced Sep 14, 2026, 4:03 AM EDT
Withdrawn Not applicable Interventional

COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia

NCT04381923
View directory record Official record
Conditions
Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure, Pneumonia, Viral, COVID
Interventions
Helmet Continuous Positive Airway Pressure (CPAP), High Flow Nasal Oxygen (HFNO)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Sep 14, 2026, 4:03 AM EDT
Completed No phase listed Observational

Effects of Long-Term Treatment With Nasally Inhaled Triamcinolone Acetonide in Children With Allergic Rhinitis

NCT00189449
View directory record Official record
Conditions
Allergic Rhinitis, Allergy, Growth
Interventions
Not listed
Lead sponsor
West Penn Allegheny Health System
Other
Eligibility
6 Years to 13 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2008 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

A Comparison of the Detection of Hypoventilation During Deep Sedation Utilizing Nasal End Title CO@ Versus Transcutaneous CO2 Measurement Techniques

NCT00954733
View directory record Official record
Conditions
Surgery, Hypoventilation
Interventions
Arterial blood draw
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional

The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study

NCT00739115
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Heliox gas
Other
Lead sponsor
Hawaii Pacific Health
Other
Eligibility
1 Minute to 12 Hours
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

The Evaluation of a Mask for the Treatment of Obstructive Sleep Apnea

NCT03142438
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
F&P Seal Improvement Project
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 14, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Obstructive Sleep Apnea in World Trade Center Responders

NCT01753999
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Standard CPAP, CPAP - Flex
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
3
States / cities
Piscataway, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 14, 2026, 4:03 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Thermal Imaging as a Potential Diagnostic Tool of Nasal Airflow

NCT03233373
View directory record Official record
Conditions
Nasal Airway Obstruction
Interventions
Seek CompactPro thermal imager
Device
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 14, 2026, 4:03 AM EDT
Completed No phase listed Observational

Nasal Continuous Positive Airway Pressure and Airway Patency in Obese Patient

NCT03024723
View directory record Official record
Conditions
Obese
Interventions
nasal mask CPAP
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Sep 14, 2026, 4:03 AM EDT