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Showing 1–24 of 368 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Progression After Ceasing Myopia Control Contact Lens Wear

NCT01829230
Conditions
Myopia
Interventions
1 Day Acuvue Moist
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
9 Years to 13 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Presbyopia, Refractive Errors, Eye Diseases
Interventions
Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution
Drug
Lead sponsor
LENZ Therapeutics, Inc
Other
Eligibility
45 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Glendale, California • Indianapolis, Indiana • Andover, Massachusetts + 2 more
Conditions
Cataract
Interventions
Odyssey intraocular lens
Device
Lead sponsor
Center For Sight
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Venice, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction With Contoura Vision Topography-Guided LASIK

NCT04903301
Conditions
Myopia, Astigmatism
Interventions
Contoura Vision LASIK
Procedure
Lead sponsor
Rush Eye Associates
Other
Eligibility
21 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Amarillo, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Comparison Between Comfilcon A and Senofilcon C Lenses

NCT02920957
Conditions
Myopia
Interventions
comfilcon A, senofilcon C
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
5
States / cities
Whittier, California • Ocoee, Florida • Edina, Minnesota + 2 more
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms

NCT05285553
Conditions
Myopia
Interventions
MiSight 1 Day, Proclear 1 day
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2030
U.S. locations
30
States / cities
Birmingham, Alabama • Fullerton, California • La Mesa, California + 26 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Light on the Choroid and Pupil

NCT05852782
Conditions
Emmetropia, Myopia
Interventions
White Light therapy, Blue light therapy, Red light therapy, Darkness
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System

NCT03278223
Conditions
Myopia, Hyperopia
Interventions
Test solution, Control solution
Device
Lead sponsor
OTE North America
Industry
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Sarasota, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

Initial Evaluation of Photorefractive Keratectomy in U.S. Army Personnel

NCT00413673
Conditions
Myopia
Interventions
PRK
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Response to Atropine Drops (RAD) Study

NCT05199597
Conditions
Myopia
Interventions
0.01% atropine, 0.05% atropine
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Conditions
Myopia, Hyperopia
Interventions
Femtosecond Laser System, LASIK surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

NCT02565537
Conditions
Nearsightedness, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Recruiting No phase listed Observational Accepts healthy volunteers

Longitudinal Measurements of Visual Diet in Children

NCT07642999
Conditions
Myopia, Visual Diet, Pupil, Viewing Distance, Illuminance, Wavelength, Vergence, Accommodative Facility
Interventions
Not listed
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
7 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Conditions
Myopia
Interventions
etafilcon A (A), etafilcon A (B), etafilcon A (C)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
6
States / cities
Cupertino, California • Los Angeles, California • San Jose, California + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Completed Not applicable Interventional Results available

Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses

NCT02185105
Conditions
Myopia, Astigmatism
Interventions
comfilcon A MTO, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Myopia, Accommodation
Interventions
Multifocal soft contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Refractive Errors, Astigmatism
Interventions
SynergEyes A2 Hybrid Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
10
States / cities
Campbell, California • Carlsbad, California • Encino, California + 7 more
Conditions
Posterior Vitreous Detachment, Myopic Vitreopathy, VISION DEGRADING MYODESOPSIA
Interventions
Neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser therapy
Device
Lead sponsor
VMR Consulting, Inc.
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Huntington Beach, California