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ClinicalTrials.gov public records Last synced Oct 24, 2026, 11:14 AM EDT

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Showing 1–24 of 385 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Nearsightedness Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Progression After Ceasing Myopia Control Contact Lens Wear

NCT01829230
View directory record Official record
Conditions
Myopia
Interventions
1 Day Acuvue Moist
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
9 Years to 13 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

NCT05294328
View directory record Official record
Conditions
Presbyopia, Refractive Errors, Eye Diseases
Interventions
Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution
Drug
Lead sponsor
LENZ Therapeutics, Inc
Other
Eligibility
45 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Glendale, California • Indianapolis, Indiana • Andover, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 24, 2026, 11:14 AM EDT
Not listed Phase 4 Interventional

A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket

NCT03376412
View directory record Official record
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Whitten Laser Eye
Other
Eligibility
40 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Oct 24, 2026, 11:14 AM EDT
Recruiting Phase 4 Interventional

Odyssey Evaluation in Post LASIK Patients

NCT07260695
View directory record Official record
Conditions
Cataract
Interventions
Odyssey intraocular lens
Device
Lead sponsor
Center For Sight
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Venice, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction With Contoura Vision Topography-Guided LASIK

NCT04903301
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura Vision LASIK
Procedure
Lead sponsor
Rush Eye Associates
Other
Eligibility
21 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Comparison Between Comfilcon A and Senofilcon C Lenses

NCT02920957
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A, senofilcon C
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
5
States / cities
Whittier, California • Ocoee, Florida • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 24, 2026, 11:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
View directory record Official record
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2024 · Synced Oct 24, 2026, 11:14 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms

NCT05285553
View directory record Official record
Conditions
Myopia
Interventions
MiSight 1 Day, Proclear 1 day
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2030
U.S. locations
30
States / cities
Birmingham, Alabama • Fullerton, California • La Mesa, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
View directory record Official record
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Light on the Choroid and Pupil

NCT05852782
View directory record Official record
Conditions
Emmetropia, Myopia
Interventions
White Light therapy, Blue light therapy, Red light therapy, Darkness
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System

NCT03278223
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Test solution, Control solution
Device
Lead sponsor
OTE North America
Industry
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Sarasota, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Initial Evaluation of Photorefractive Keratectomy in U.S. Army Personnel

NCT00413673
View directory record Official record
Conditions
Myopia
Interventions
PRK
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

NCT00413868
View directory record Official record
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Response to Atropine Drops (RAD) Study

NCT05199597
View directory record Official record
Conditions
Myopia
Interventions
0.01% atropine, 0.05% atropine
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
View directory record Official record
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study

NCT02575911
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Femtosecond Laser System, LASIK surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

NCT02565537
View directory record Official record
Conditions
Nearsightedness, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 24, 2026, 11:14 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Longitudinal Measurements of Visual Diet in Children

NCT07642999
View directory record Official record
Conditions
Myopia, Visual Diet, Pupil, Viewing Distance, Illuminance, Wavelength, Vergence, Accommodative Facility
Interventions
Not listed
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
7 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)

NCT01180777
View directory record Official record
Conditions
Myopia
Interventions
etafilcon A (A), etafilcon A (B), etafilcon A (C)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
6
States / cities
Cupertino, California • Los Angeles, California • San Jose, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses

NCT02185105
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
comfilcon A MTO, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Oct 24, 2026, 11:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dynamic Change in Accommodation After Wearing Multifocal Soft Contact Lenses for Myopia Control

NCT04763694
View directory record Official record
Conditions
Myopia, Accommodation
Interventions
Multifocal soft contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 24, 2026, 11:14 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses

NCT01058629
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
SynergEyes A2 Hybrid Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
10
States / cities
Campbell, California • Carlsbad, California • Encino, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 24, 2026, 11:14 AM EDT