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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Neck Pain Clear all
Active, not recruiting Not applicable Interventional

Neurofeedback in Decreasing Acute Radiotherapy-Induced Pain in Patients With Head and Neck Cancer

NCT02543320
View directory record Official record
Conditions
Head and Neck Carcinoma
Interventions
LORETA Neurofeedback Training, Questionnaire Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 21, 2026, 1:03 AM EDT
Recruiting Not applicable Interventional

Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural Populations

NCT07179016
View directory record Official record
Conditions
Chronic Pain (Back / Neck), Chronic Pain Management, Chronic Knee Pain, Joint Pain
Interventions
Auricular Point Acupressure (APA) - Self Management (SM), Education Control
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 85 Years
Enrollment
693 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Columbia, South Carolina • Fort Worth, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional

Electroacupuncture and Laser Therapy on Neck Pain

NCT00618878
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Electroacupuncture, Laser Therapy
Procedure
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2008 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Dry Needling for Patients With Neck Pain

NCT02731014
View directory record Official record
Conditions
Neck Pain
Interventions
Dry Needling, Sham Dry Needling, Manual Therapy, Exercise
Other
Lead sponsor
Franklin Pierce University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Indianapolis, Indiana • Concord, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Pain Control Using Neuromodulation in Patients Undergoing Definitive Chemoradiotherapy for Head and Neck Cancer

NCT02366611
View directory record Official record
Conditions
Cancer of Head and Neck
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 21, 2026, 1:03 AM EDT
Recruiting Phase 1Phase 2 Interventional

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

NCT05156060
View directory record Official record
Conditions
Head and Neck Cancer, Locally Advanced Head and Neck Carcinoma
Interventions
Gabapentin, Ketamine
Drug
Lead sponsor
Natalie Lockney
Other
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 20, 2024 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Results available

Trigger Point Injections in Anterior Cervical Surgery

NCT04640896
View directory record Official record
Conditions
Myofacial Pain, Pain, Neck, Pain, Back, Cervical Fusion
Interventions
Trigger point injection with bupivacaine, Trigger point injection with normal saline, Lidocaine skin wheal
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heartache and Backache- An Online Intervention Addressing Emotional and Physical Pain

NCT05513274
View directory record Official record
Conditions
Chronic Pain (Back / Neck)
Interventions
Pain Psychology Neuroscience + Written Emotional Disclosure, Pain Psychology Neuroscience + Healthy Habits Disclosure, Health Behavior Control + Written Emotional Disclosure, Health Behavior Control + Healthy Habits Disclosure
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 75 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 21, 2026, 1:03 AM EDT
Suspended Not applicable Interventional

A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain

NCT02972710
View directory record Official record
Conditions
Neck Pain
Interventions
Supine thoracic spine thrust manipulation, Seated thoracic spine thrust manipulation
Other
Lead sponsor
Northern Arizona University
Other
Eligibility
20 Years to 50 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 21, 2026, 1:03 AM EDT
Terminated Not applicable Interventional

Evaluating Different Low-level Laser Therapies to Treat Neck Pain in Air Force Pilots and Flight Crew

NCT03945240
View directory record Official record
Conditions
Neck Pain
Interventions
Group 1 -- using Pinnacle Series Laser Device, Group 2 -- using Pinnacle Series Laser Device, Group 3 -- using Phoenix Thera-Lase Device
Procedure
Lead sponsor
Paul Crawford
Federal
Eligibility
18 Years to 62 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 21, 2026, 1:03 AM EDT
Not yet recruiting Not applicable Interventional

Musical Mindfulness for Pain in the ED Waiting Room

NCT07391891
View directory record Official record
Conditions
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
Interventions
Music intervention
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Chiropractic Manipulation Versus Medical Therapy for Chronic Neck Pain

NCT00429624
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic manipulation, acetaminophen
Procedure · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 4, 2013 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional Results available

Study of Opioid Use After Lumbar and Cervical Spine Surgery

NCT02674711
View directory record Official record
Conditions
Low Back Pain, Opiate Addiction, Neck Pain
Interventions
Educational Video
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Results available

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

NCT00320281
View directory record Official record
Conditions
Spinal Cord Injury, Pain
Interventions
botulinum toxin A, placebo
Drug · Other
Lead sponsor
Craig Hospital
Other
Eligibility
15 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 21, 2026, 1:03 AM EDT
Active, not recruiting Not applicable Interventional

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

NCT06906107
View directory record Official record
Conditions
Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
Interventions
Cervical Manipulation, Exercise, Mobilization
Procedure
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Rochester, Minnesota • Syracuse, New York • Waco, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional

Thrust Manipulation vs. Non-thrust Mobilizations for Mechanical Neck Pain

NCT02619500
View directory record Official record
Conditions
Neck Pain
Interventions
Home Exercise Program, Patient advice, encouragement, and education, Thrust Manipulation, Non-thrust Mobilizations
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Sep 21, 2026, 1:03 AM EDT
Terminated Phase 4 Interventional Results available

Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance

NCT01681264
View directory record Official record
Conditions
Chronic Pain
Interventions
Morphine, Guanfacine 1mg, Guanfacine 2mg, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 21, 2026, 1:03 AM EDT
Completed No phase listed Observational

Effects of Physical Therapy on Isometric Neck Retraction Strength and Pain in Patients With Neck Disability

NCT04334655
View directory record Official record
Conditions
Neck Pain, Strength
Interventions
Physical Therapy
Other
Lead sponsor
Campbell University, Incorporated
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Firestone, Colorado • Cos Cob, Connecticut • Granby, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Comparison of Outcomes Between Early Physical Therapy Intervention and Usual Care Following Anterior Cervical Fusion Surgery

NCT01519115
View directory record Official record
Conditions
Cervical Spine Degenerative Disc Disease, Fusion of Spine, Cervical Region
Interventions
early physical therapy intervention, usual care
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Tenaculum Pain Control Study

NCT01421641
View directory record Official record
Conditions
Cervical Pain, Pelvic Pain
Interventions
Intracervical Lidocaine Injection, Topical Lidocaine Gel
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional

The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain

NCT01760590
View directory record Official record
Conditions
Neck Pain, Cervical Pain
Interventions
Manual Manipulation, Mobilization
Procedure
Lead sponsor
Keystone Rehabilitation Systems
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Bridgeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 3, 2013 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Phase 4 Interventional Results available

Effect of Combined Morphine and Duloxetine on Chronic Pain

NCT03249558
View directory record Official record
Conditions
Chronic Low Back Pain, Chronic Neck Pain
Interventions
Morphine, Duloxetine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Sep 21, 2026, 1:03 AM EDT
Completed Not applicable Interventional

Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries

NCT02157038
View directory record Official record
Conditions
Whiplash Associated Disorders, WAD, Whiplash
Interventions
Pedometer, MRI
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 21, 2026, 1:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Novel Cervical Retraction Device

NCT02283463
View directory record Official record
Conditions
Pain Due to Certain Specified Procedures
Interventions
Intrauterine device (IUD) insertion, Endometrial biopsy
Device · Procedure
Lead sponsor
Bioceptive
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 21, 2026, 1:03 AM EDT