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ClinicalTrials.gov public records Last synced Oct 2, 2026, 4:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Needle Biopsy Clear all
Withdrawn No phase listed Observational

Correlation of X-ray and Pathology With Needle Biopsy of Lung Tumors

NCT00638625
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Phase 2 Interventional

Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer

NCT00003099
View directory record Official record
Conditions
Breast Cancer
Interventions
Fenretinide, Tamoxifen Citrate, Placebo
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2003
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional

The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy

NCT02489617
View directory record Official record
Conditions
Flat Epithelia Atypia, Intraductal Papilloma Without Atypia
Interventions
Pathologic evaluation of excised tissue
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
18
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Indianapolis, Indiana + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 2, 2026, 4:51 AM EDT
Completed No phase listed Observational

EchoTip AcuCore Post-Market Clinical Study

NCT06358001
View directory record Official record
Conditions
Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma, Malignant Lymphoma, Metastasis, Chronic Pancreatitis, Autoimmune Pancreatitis
Interventions
EchoTip AcuCore
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Orange, California • Denver, Colorado • Gainesville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

NCT03408171
View directory record Official record
Conditions
Abnormal Liver Function
Interventions
19-gauge FNA needle, 19-gauge FNB needle
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Phase 4 Interventional

Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms

NCT01673334
View directory record Official record
Conditions
Pancreatic Tumor
Interventions
Fine Needle Aspiration (FNA) and Core biopsy (FNB)
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 2, 2026, 4:51 AM EDT
Active, not recruiting No phase listed Observational

AI for Onsite Cytology Evaluation in Endoscopic Ultrasound

NCT07228689
View directory record Official record
Conditions
Gastrointestinal Neoplasm, Mass Lesion
Interventions
EUS-guided fine needle biopsy
Diagnostic Test
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 2, 2026, 4:51 AM EDT
Terminated Not applicable Interventional Results available

EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors

NCT02282111
View directory record Official record
Conditions
Esophageal Subepithelial Lesions
Interventions
22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Oct 2, 2026, 4:51 AM EDT
Recruiting No phase listed Observational

Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)

NCT07029256
View directory record Official record
Conditions
Bladder Urothelial Carcinoma
Interventions
Non-Interventional Study
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

EUS-guided Fine Needle Aspiration (FNA) With and Without the Use of a Stylet

NCT01316614
View directory record Official record
Conditions
Biopsy, Fine-Needle, Biopsy, Fine-Needle/Methods, Endosonography
Interventions
FNA with and without a stylet
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Phase 1Phase 2 Interventional

Utility of Endobronchial Ultrasound Guided Needle Biopsy in Early Stage Non- Small Cell Lung Cancer (NSCLC)

NCT00832715
View directory record Official record
Conditions
Lung Cancer
Interventions
EBUS-TBNA
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2016 · Synced Oct 2, 2026, 4:51 AM EDT
Withdrawn Phase 2 Interventional

Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)

NCT02766842
View directory record Official record
Conditions
Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
Interventions
EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle, SharkCore needle
Procedure · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses

NCT02911974
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 2, 2026, 4:51 AM EDT
Recruiting Phase 2 Interventional

Cryoablation+Ipilimumab+Nivolumab in Melanoma

NCT05779423
View directory record Official record
Conditions
Metastatic Melanoma, Skin Cancer
Interventions
Ipilimumab, Nivolumab, Cryoablation
Drug · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

19 Versus 22-Gauge Needle for EUS-LB

NCT02967991
View directory record Official record
Conditions
Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
Interventions
EUS-guided liver biopsy
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 2, 2026, 4:51 AM EDT
Not yet recruiting Not applicable Interventional

Comparison of FNB to EUS-CNB for Pancreatic Lesions

NCT07240818
View directory record Official record
Conditions
Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
Interventions
endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
Device · Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 2, 2026, 4:51 AM EDT
Not listed Not applicable Interventional

Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions

NCT01698190
View directory record Official record
Conditions
Pancreatic Tumor, Gastric Tumor, Esophageal Tumor, Lymphadenopathy, Duodenal Tumor
Interventions
Endoscopic ultrasound guided needle tissue acquisition.
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

NCT01769248
View directory record Official record
Conditions
Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
Interventions
Fine needle aspiration, Fine needle biopsy
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional Results available

Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS

NCT02167074
View directory record Official record
Conditions
Pancreatic Masses, Lymph Nodes
Interventions
25G FNA needle, 20G ProCore FNB needle
Device
Lead sponsor
Foundation for Liver Research
Other
Eligibility
18 Years to 100 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
Irvine, California • New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Oct 2, 2026, 4:51 AM EDT
Not listed Not applicable Interventional

Ultrasound-CT Fusion System for Interventional Radiology Procedures

NCT03226535
View directory record Official record
Conditions
CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis, CT Guided Injection of Muscle or Nerve Within the Pelvis
Interventions
Ultrasound-CT Fusion
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 2, 2026, 4:51 AM EDT
Recruiting No phase listed Observational

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

NCT07327489
View directory record Official record
Conditions
Cancer, Immunotherapy, Advanced Solid Tumors Cancer, Bladder Cancer, TNBC, Triple Negative Breast Cancer, Colorectal Cancer, DMMR Colorectal Cancer, MSI-H Colorectal Cancer, Endometrial Cancer, Head and Neck Cancer, Kidney Cancer, Liver Cancer, NSCLC (Non-small-cell Lung Cancer), Skin Cancer, Melanoma (Skin Cancer)
Interventions
Biopsy
Procedure
Lead sponsor
Elephas
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2038
U.S. locations
8
States / cities
Fort Smith, Arkansas • Frederick, Maryland • Springfield, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 2, 2026, 4:51 AM EDT
Completed Not applicable Interventional

Comparison of Two Types of Biopsy in Patients With Breast Lesions

NCT00006031
View directory record Official record
Conditions
Breast Cancer
Interventions
Needle localized breast biopsy with specimen x-ray, Low dose radioactive seed followed by surgery and mammogram
Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 26, 2012 · Synced Oct 2, 2026, 4:51 AM EDT
Completed No phase listed Observational

False/Negative Rate of Lung Percutaneous Needle Biopsy

NCT00638352
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 2, 2026, 4:51 AM EDT
Recruiting No phase listed Observational

Artificial Intelligence (AI) Cytopathology Trial

NCT05018663
View directory record Official record
Conditions
Pancreatic Solid Lesions
Interventions
Artificial Intelligence software ROSE
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 2, 2026, 4:51 AM EDT