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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Negative Pressure Therapy Clear all
Withdrawn Phase 4 Interventional

Comparative Effectiveness Study of MIST Therapy Versus Negative Pressure Wound Therapy

NCT01200563
View directory record Official record
Conditions
Wounds
Interventions
MIST Therapy, Vacuum Assisted Closure, MIST Therapy and Negative Pressure Wound Therapy
Device
Lead sponsor
Celleration, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 14, 2014 · Synced Sep 23, 2026, 1:44 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers

NCT01208220
View directory record Official record
Conditions
Pressure Ulcer, Soft Tissue Necrosis Lower Limb
Interventions
Negative Pressure Wound Therapy, Collagenase Ointment
Device · Biological
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 16, 2014 · Synced Sep 23, 2026, 1:44 PM EDT
Terminated Not applicable Interventional Results available

Incisional Negative Pressure Wound Therapy

NCT01759381
View directory record Official record
Conditions
Spinal Deformity
Interventions
Negative pressure wound therapy (NPWT)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2015 · Synced Sep 23, 2026, 1:44 PM EDT
Recruiting Not applicable Interventional

Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure

NCT05675345
View directory record Official record
Conditions
Acute Hypoxemic Respiratory Failure
Interventions
HFNC only, HFNC + CNEP10, HFNC + CNEP20, HFNC + CNEP30
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2024 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

PICO Breast Reduction Clinical Study Looking at Incision Healing Complications

NCT01640366
View directory record Official record
Conditions
Delayed Healing
Interventions
PICO
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • The Bronx, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA

NCT03321799
View directory record Official record
Conditions
Infection, Drainage
Interventions
Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 23, 2026, 1:44 PM EDT
Withdrawn Not applicable Interventional

Incisional Negative Pressure Dressing on Clean Closed Groin Incisions

NCT02006511
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
Incisional Neg Pressure Wound Therapy (Prevena™), Standard of Care wound therapy
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 23, 2026, 1:44 PM EDT
Not listed No phase listed Observational

Negative Pressure Wound Therapy Registry

NCT02467998
View directory record Official record
Conditions
Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence, Burns, Other Types of Chronic Non Healing Wounds
Interventions
NPWT
Device
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

Closed Incision Negative Pressure Therapy vs Standard of Care

NCT03061903
View directory record Official record
Conditions
Wound Complication
Interventions
Prevena, Aquacel
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 23, 2026, 1:44 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Needle-Aspirated Compression Dressing Following Ostomy Reversal

NCT03703661
View directory record Official record
Conditions
Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
Interventions
Needle-Aspirated Negative Pressure Dressing, Control
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Sep 23, 2026, 1:44 PM EDT
Recruiting Not applicable Interventional

NPWT Reduction Mammaplasty

NCT06725459
View directory record Official record
Conditions
Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions
Prophylactic ciNPWT, Standard Adhesive Dressing
Device · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy After Cesarean Delivery

NCT01637870
View directory record Official record
Conditions
Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions
Prevena negative pressure wound system
Device
Lead sponsor
Abbey Hardy-Fairbanks
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Sep 23, 2026, 1:44 PM EDT
Withdrawn Not applicable Interventional

Negative Pressure Wound Therapy for Surgical Site Infection Prevention in Common Femoral Artery Exposure

NCT03935659
View directory record Official record
Conditions
Surgical Site Infection, Groin Infections
Interventions
Negative Pressure Pressure Wound Therapy, Standard Wound Care
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Phase 4 Interventional Results available

Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions

NCT02137447
View directory record Official record
Conditions
High Risk Abdominal Wounds
Interventions
Negative Pressure treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

NCT01656044
View directory record Official record
Conditions
Colon Cancer, Pancreatic Cancer, Perioperative/Postoperative Complications, Primary Peritoneal Cavity Cancer, Rectal Cancer
Interventions
wound care management
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Sep 23, 2026, 1:44 PM EDT
Withdrawn Not applicable Interventional

Continuous Negative External Pressure for the Treatment of Primary Snoring

NCT03372070
View directory record Official record
Conditions
Snoring
Interventions
cNEP
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Negative Pressure Wound Therapy in Cesarean Section

NCT02289157
View directory record Official record
Conditions
Postoperative Wound Complications
Interventions
Negative pressure wound therapy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years to 64 Years · Female only
Enrollment
441 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2018 · Synced Sep 23, 2026, 1:44 PM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

Imaging Biomarkers of Lymphatic Dysfunction

NCT03760744
View directory record Official record
Conditions
Secondary Lymphedema
Interventions
CDT with Negative Pressure, CDT alone
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
30 Years to 90 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy to Reduce Surgical Site Infection

NCT01905397
View directory record Official record
Conditions
Patients Undergoing Hepatopancreatobiliary Surgery
Interventions
Conventional wound therapy, Negative pressure wound therapy
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study

NCT04718142
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
vNEP
Device
Lead sponsor
Somne, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional Results available

SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds

NCT00951080
View directory record Official record
Conditions
Ulcers, Wounds
Interventions
Traditional NPWT System, SNaP Wound Care System
Device
Lead sponsor
3M
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
17
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 23, 2026, 1:44 PM EDT
Withdrawn No phase listed Observational

Study of Avelle™ Negative Pressure Wound Therapy (NPWT) System

NCT05805046
View directory record Official record
Conditions
Surgical Wound, Recent, Surgical Wound Leak, Dehiscence Wound, Trauma-related Wound
Interventions
Negative Pressure Wound Therapy System
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
4
States / cities
Miami Lakes, Florida • Chicago, Illinois • Lake Success, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 23, 2026, 1:44 PM EDT
Completed Not applicable Interventional

Evaluating Blast-X® in Combination With Negative Pressure Wound Therapy

NCT04265170
View directory record Official record
Conditions
Pressure Ulcer
Interventions
BlastX with negative pressure therapy
Device
Lead sponsor
SerenaGroup, Inc.
Network
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kittanning, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 23, 2026, 1:44 PM EDT