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ClinicalTrials.gov public records Last synced Oct 6, 2026, 6:08 AM EDT

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Showing 25–48 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neisseria Gonorrhoeae Infection Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae

NCT05294588
View directory record Official record
Conditions
Gonorrhea Male
Interventions
Cefixime, Ceftriaxone, Ciprofloxacin, Neisseria gonorrhoeae strain FA1090, Meningococcal Group B Vaccine, Influenza Vaccine, Tetanus-diptheria Vaccine
Drug · Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT

NCT02870101
View directory record Official record
Conditions
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection, Sexually Transmitted Infections
Interventions
Nucleic acid amplification test 1 for NG and CT, Nucleic acid amplification test 2 for NG and CT, Nucleic acid amplification test 3 for NG and CT
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2,767 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
9
States / cities
Hollywood, California • Los Angeles, California • Denver, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

HIV and STD Prevention for High-Risk, Inner-City, African American Youth

NCT00353405
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
Social Skills Training, Mass media, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
14 Years to 17 Years
Enrollment
1,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
4
States / cities
Atlanta, Georgia • Syracuse, New York • Providence, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2012 · Synced Oct 6, 2026, 6:08 AM EDT
Completed No phase listed Observational

Antimicrobial Susceptibility Patterns of N. Gonorrhea Isolates in an Era of Quinolone Resistance

NCT00692822
View directory record Official record
Conditions
Gonorrhea
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 6, 2026, 6:08 AM EDT
Terminated Phase 3 Interventional Results available

Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea

NCT02015637
View directory record Official record
Conditions
Gonorrhea
Interventions
Delafloxacin, Ceftriaxone
Drug
Lead sponsor
Melinta Therapeutics, Inc.
Industry
Eligibility
15 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
25
States / cities
Birmingham, Alabama • Chula Vista, California • La Mesa, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2018 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional

Randomized Trial of Advanced Provision Emergency Contraception Among Women With Gonorrhea or Chlamydia

NCT00520455
View directory record Official record
Conditions
Pregnancy
Interventions
levonorgestrel 0.75mg taken twice 12 hours apart (Plan B) and condoms
Drug
Lead sponsor
University of Washington
Other
Eligibility
16 Years to 60 Years · Female only
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 15, 2007 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin

NCT02348424
View directory record Official record
Conditions
Gonorrhoea
Interventions
Solithromycin
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914

NCT01929629
View directory record Official record
Conditions
Gonococcal (GC) Infection
Interventions
Part A, Part B
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2014 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 4 Interventional

Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women

NCT00628771
View directory record Official record
Conditions
Pregnancy, HIV Infections, Sexually Transmitted Diseases
Interventions
CenteringPregnancy Plus (CP+), Usual care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 21 Years · Female only
Enrollment
1,233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
New Haven, Connecticut • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Experimental Human Infection With Neisseria Gonorrhoeae

NCT03840811
View directory record Official record
Conditions
Gonococcal Infection
Interventions
Cefixime, Ceftriaxone, Ciprofloxacin, Neisseria gonorrhoeae strain FA1090 A26, Neisseria gonorrhoeae strain FA7537
Drug · Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 36 Years · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Oct 6, 2026, 6:08 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Use of Abbott RealTime CT/NG to Detect Chlamydia Trachomatis [CT] & Neisseria Gonorrhoeae [NG] in Men Who Have Sex With Men [MSM]

NCT01291264
View directory record Official record
Conditions
Chlamydia Infection, Gonococcal Infection, Sexually Transmitted Diseases
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)

NCT03896776
View directory record Official record
Conditions
HIV/AIDS, Gonorrhea, Chlamydia
Interventions
Keep It Up! 3.0
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
2,125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of an Adapted STD Screening and Risk Reduction Intervention

NCT02513225
View directory record Official record
Conditions
Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions
Project EMPWR, Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 49 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Fort Apache, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 2 Interventional Results available

A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

NCT02294682
View directory record Official record
Conditions
Gonorrhea
Interventions
GSK2140944
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
12
States / cities
Fountain Valley, California • Los Angeles, California • Palm Springs, California + 8 more
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Oct 6, 2026, 6:08 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Improving Clinic Delivery of HIV-related Anal Health Services

NCT07464236
View directory record Official record
Conditions
HIV, Gonorrhea, Chlamydia, Anal Cancer Squamous Cell
Interventions
PEACHES 2.0 Implementation Strategies
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Biloxi, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs

NCT05666778
View directory record Official record
Conditions
Bacterial Vaginosis, Vaginal Microbiome, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginitis
Interventions
Menstrual Cup
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
15 Years to 35 Years · Female only
Enrollment
408 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 3 Interventional Results available

Zoliflodacin in Uncomplicated Gonorrhoea

NCT03959527
View directory record Official record
Conditions
Gonorrhea
Interventions
zoliflodacin, ceftriaxone, azithromycin
Drug
Lead sponsor
Global Antibiotics Research and Development Partnership
Other
Eligibility
12 Years and older
Enrollment
1,011 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
6
States / cities
Birmingham, Alabama • San Francisco, California • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men

NCT01836445
View directory record Official record
Conditions
HIV, Gonorrhea, Chlamydia
Interventions
Keep It Up!, HIV Knowledge Control
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
901 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
3
States / cities
Atlanta, Georgia • Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2022 · Synced Oct 6, 2026, 6:08 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of the Aptima® Combo 2® Assay Using the Panther® System in Female Urine Samples

NCT02795975
View directory record Official record
Conditions
Chlamydia Trachomatis, Gonorrhea
Interventions
Not listed
Lead sponsor
Hologic, Inc.
Industry
Eligibility
14 Years and older · Female only
Enrollment
1,766 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
18
States / cities
Birmingham, Alabama • New Haven, Connecticut • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2017 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Phase 4 Interventional

Washington State Community Expedited Partner Treatment (EPT) Trial

NCT01665690
View directory record Official record
Conditions
Gonorrhea, Neisseria Gonorrhoeae, Chlamydia Trachomatis
Interventions
Patient delivered partner therapy, Targeted public health partner services
Other · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
33,222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Olympia, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 17, 2012 · Synced Oct 6, 2026, 6:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing Acceptability and Feasibiity of STI Self-swab Testing, to be Offered at the Time of Telemed Medication Abortion Provision

NCT06951438
View directory record Official record
Conditions
Sexually Transmitted Disease (STD), Gonorrhea, Chlamydia, Trichomonas Infection
Interventions
Self-swab collection PCR test for chlamydia, gonorrhea, trichomonas
Diagnostic Test
Lead sponsor
Queen's Medical Center
Other
Eligibility
14 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 6, 2026, 6:08 AM EDT
Completed Not applicable Interventional

Self Sampling for Rapid Turnaround Testing in the Emergency Department

NCT03676816
View directory record Official record
Conditions
Chlamydia Trachomatis, Neisseria Gonorrhoeae
Interventions
vaginal self sampling, provider-performed endocervical sampling
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
533 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 6, 2026, 6:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women

NCT04098900
View directory record Official record
Conditions
Chlamydial Infection, Gonococcal Infection, Trichomoniasis
Interventions
Click Sexual Health Test
Diagnostic Test
Lead sponsor
Visby Medical
Industry
Eligibility
14 Years to 99 Years · Female only
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
5
States / cities
Fort Lauderdale, Florida • Saint Paul, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 6, 2026, 6:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Emergency Department, Rapid Assessment for Sexually Transmitted Infection

NCT02386514
View directory record Official record
Conditions
Infection
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Oct 6, 2026, 6:08 AM EDT