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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Neonatal Hyperbilirubinemia Clear all
No Longer Available No phase listed Expanded access

Compassionate Use of Stanate (TM) [Stannsoporfin]

NCT00076960
View directory record Official record
Conditions
Neonatal Jaundice, Hyperbilirubinemia
Interventions
Stanate (TM) [stannsoporfin, tin-mesoporphyrin]
Drug
Lead sponsor
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Industry
Eligibility
12 Hours to 1 Week
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Jul 21, 2026, 7:04 AM EDT
Active, not recruiting Not applicable Interventional

Cycled Phototherapy

NCT03927833
View directory record Official record
Conditions
Hyper Bilirubinemia, Premature Infant
Interventions
Phototherapy lights
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
22 Weeks to 27 Weeks
Enrollment
1,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jul 21, 2026, 7:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Smartphone-based Screening Tool (Picterus JP) for Neonatal Jaundice (Chicago)

NCT05521607
View directory record Official record
Conditions
Neonatal Jaundice
Interventions
Picterus Jaundice Pro (JP)
Device
Lead sponsor
Picterus AS
Industry
Eligibility
1 Day to 14 Days
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 21, 2026, 7:04 AM EDT
Withdrawn Not applicable Interventional

Development of a Neonatal Jaundice Treatment Accelerator by Redirection of Unused Light During Phototherapy

NCT04021927
View directory record Official record
Conditions
Jaundice, Jaundice, Neonatal
Interventions
Ring Phototherapy
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 7 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Jul 21, 2026, 7:04 AM EDT
Completed Phase 2 Interventional Results available

Stannsoporfin With Light Therapy for Newborn Babies With Jaundice

NCT01887327
View directory record Official record
Conditions
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Interventions
Phototherapy, Stannsoporfin, Placebo
Procedure · Drug
Lead sponsor
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Industry
Eligibility
1 Hour to 72 Hours
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
18
States / cities
Colton, California • San Diego, California • San Francisco, California + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia

NCT00383318
View directory record Official record
Conditions
Hyperbilirubinemia, Jaundice
Interventions
Gene mutation sample
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
Up to 6 Days
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2008 · Synced Jul 21, 2026, 7:04 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Stannsoporfin in Neonates

NCT02685137
View directory record Official record
Conditions
Nutritional and Metabolic Diseases
Interventions
stannsoporfin, Sham Injection
Drug · Other
Lead sponsor
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Industry
Eligibility
12 Hours to 36 Hours
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Jul 21, 2026, 7:04 AM EDT
Terminated Phase 1 Interventional

Hepatocyte Transplantation for Liver Based Metabolic Disorders

NCT01345578
View directory record Official record
Conditions
Metabolic Diseases
Interventions
human hepatocyte transplantation, Preparative Radiation Therapy
Drug · Radiation
Lead sponsor
Ira Fox
Other
Eligibility
Up to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

BiliCam Clinical Validation Study

NCT03246503
View directory record Official record
Conditions
Newborn Jaundice
Interventions
BiliCam estimated bilirubin (BCB)
Device
Lead sponsor
BiliCam, LLC
Industry
Eligibility
0 Hours to 191 Hours
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bilicurves: Using Information Technology to Improve the Management of Neonatal Hyperbilirubinemia

NCT00801619
View directory record Official record
Conditions
Neonatal Hyperbilirubinemia
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Up to 1 Month
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Jul 21, 2026, 7:04 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Intermountain Inpatient Bilirubin Decision Accuracy Study Using Smartphone-based Measurements by Picterus Jaundice Pro

NCT06329843
View directory record Official record
Conditions
Neonatal Jaundice
Interventions
Picterus Jaundice Pro (JP)
Device
Lead sponsor
Picterus AS
Industry
Eligibility
12 Hours to 192 Hours
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational

Clinical Assessment Study in Crigler-Najjar Syndrome

NCT03078881
View directory record Official record
Conditions
Crigler-Najjar Syndrome
Interventions
Not listed
Lead sponsor
Audentes Therapeutics
Industry
Eligibility
1 Year and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
The Bronx, New York • Strasburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Jul 21, 2026, 7:04 AM EDT
Not listed No phase listed Observational

Validation of a Jaundice Diagnostic and Monitoring Device for Low-Resource Settings

NCT03866213
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Interventions
BiliSpec
Diagnostic Test
Lead sponsor
William Marsh Rice University
Other
Eligibility
0 Days to 28 Days
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Jul 21, 2026, 7:04 AM EDT
Withdrawn No phase listed Observational

Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis

NCT00917007
View directory record Official record
Conditions
ABO Incompatibility, Hemolytic Disease of Newborn, Neonatal Jaundice, Neonatal Hyperbilirubinemia
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
Up to 28 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2021 · Synced Jul 21, 2026, 7:04 AM EDT
Completed Phase 3 Interventional

Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight

NCT00114543
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Aggressive Phototherapy 501-750g, Aggressive Phototherapy 751-1000g, Conservative Phototherapy 501-750g, Conservative Phototherapy 751-1000g
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
12 Hours to 36 Hours
Enrollment
1,974 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 21, 2026, 7:04 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Newborn Abdominal Massage to Prevent Hyperbilirubinemia

NCT05282394
View directory record Official record
Conditions
Newborn Jaundice
Interventions
Abdominal massage, Reading
Procedure · Other
Lead sponsor
University of California, Davis
Other
Eligibility
0 Hours to 48 Hours
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jul 21, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Comparison of Phototherapy Using Neolight Skylife Versus Standardized Phototherapy for Hyperbilirubinemia in Newborns

NCT03599258
View directory record Official record
Conditions
Jaundice, Neonatal, Neonatal Hyperbilirubinemia, Neonatal Disorder
Interventions
Skylife, Standard Therapy
Device
Lead sponsor
HonorHealth Research Institute
Other
Eligibility
0 Minutes to 7 Minutes
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prediction of Jaundice in Term Infants

NCT01203410
View directory record Official record
Conditions
Infant, Newborn, Jaundice
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Hours
Enrollment
535 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 1992
U.S. locations
13
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants

NCT02691156
View directory record Official record
Conditions
Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature, Infant, Low Birth Weight
Interventions
Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
24 Weeks to 34 Weeks
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Jul 21, 2026, 7:04 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Early Limited Formula on Total Serum Bilirubin Among Newborns With Hyperbilirubinemia

NCT01330667
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal
Interventions
Nutramigen Infant Formula
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
36 Hours to 96 Hours
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bilistick Point-of-care System 2.0 Bilirubin Validation

NCT06058910
View directory record Official record
Conditions
Neonatal Screening, Kernicterus, Newborn Jaundice, Point-of-Care Testing
Interventions
Bilistick System 2.0 point-of-care testing device
Diagnostic Test
Lead sponsor
Kettering Health Network
Other
Eligibility
Up to 2 Weeks
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kettering, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Jul 21, 2026, 7:04 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration

NCT04584983
View directory record Official record
Conditions
Bilirubin Encephalopathy
Interventions
usual prescribed intralipid (UL) regimen, restricted prescribed intralipid (RL) regimen
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 27 Weeks
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 21, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice

NCT03741803
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Interventions
Delayed cord clamping, Early cord clamping
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 21, 2026, 7:04 AM EDT
Completed No phase listed Observational

A Light Emitting Diode (LED) Mattress for Phototherapy of Jaundiced Newborns

NCT03723005
View directory record Official record
Conditions
Hyperbilirubinemia, Neonatal
Interventions
Neolight Phototherapy Mattress, Standard-of-Care
Device
Lead sponsor
Stanford University
Other
Eligibility
28 Weeks to 8 Months
Enrollment
41 participants
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Jul 21, 2026, 7:04 AM EDT