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ClinicalTrials.gov public records Last synced Jun 9, 2026, 11:44 PM EDT

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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nephrectomy Clear all
Completed Not applicable Interventional Results available

Intraoperative Folate Targeted Fluorescence in Renal Cell Carcinoma

NCT02645409
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
OTL38, Intraoperative fluorescence imaging system
Drug · Device
Lead sponsor
Chandru Sundaram
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Jun 9, 2026, 11:44 PM EDT
Active, not recruiting Phase 3 Interventional

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

NCT05239728
View directory record Official record
Conditions
Carcinoma, Renal Cell
Interventions
Belzutifan, Pembrolizumab, Placebo
Drug · Biological
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
37
States / cities
Phoenix, Arizona • Duarte, California • La Jolla, California + 31 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 9, 2026, 11:44 PM EDT
Terminated Not applicable Interventional

Comparison Study of Two Different Surgical Clips During Laparoscopic Urologic Surgery

NCT01008709
View directory record Official record
Conditions
Prostatectomy, Nephrectomy, Laparoscopy, Robotics
Interventions
Teleflex HemoLock clip, Aesculap U-clip
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Jun 9, 2026, 11:44 PM EDT
Completed No phase listed Observational Results available

Retrospective Study on Referral Patterns for High Risk Patients Post Nephrectomy

NCT04309617
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
nephrectomy
Procedure
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Jun 9, 2026, 11:44 PM EDT
Terminated Not applicable Interventional Results available

Port Site Pain Following Percutaneous Externally-Assembled Laparoscopic Donor Nephrectomy

NCT02805517
View directory record Official record
Conditions
Laparoscopic Donor Nephrectomy
Interventions
Percuvance™ Percutaneous Surgical System
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Jun 9, 2026, 11:44 PM EDT
Withdrawn Not applicable Interventional

Robot-Assisted Ultrasound for Thermal Ablative Therapy in Treating Patients With Small Kidney Masses Undergoing Surgery

NCT02370342
View directory record Official record
Conditions
Renal Carcinoma, Renal Mass
Interventions
Robot-Assisted Laparoscopic Surgery, High-Intensity Focused Ultrasound Ablation, Therapeutic Laparoscopic Surgery, Sonatherm 600i Ultrasonic Lesion Generating System
Procedure · Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Jun 9, 2026, 11:44 PM EDT
Terminated Not applicable Interventional

Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy

NCT02131376
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
Non-renorrhaphy, Renorrhaphy
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 22, 2020 · Synced Jun 9, 2026, 11:44 PM EDT
Completed Phase 3 Interventional Results available

Mannitol Use During Partial Nephrectomy Prior to Renal Ischemia and Impact on Renal Function Outcomes

NCT01606787
View directory record Official record
Conditions
Renal Cancer
Interventions
mannitol, placebo
Drug · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced Jun 9, 2026, 11:44 PM EDT
Withdrawn Phase 4 Interventional

Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies

NCT04077398
View directory record Official record
Conditions
Analgesia, Postoperative Pain, Block
Interventions
Ropivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Bruce Ben-David
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Jun 9, 2026, 11:44 PM EDT
Not listed Phase 2 Interventional

Sunitinib Before and After Surgery in Treating Patients With Stage IV Kidney Cancer

NCT00717587
View directory record Official record
Conditions
Kidney Cancer
Interventions
motexafin gadolinium, sunitinib malate, comparative genomic hybridization, gene expression analysis, mutation analysis, polymorphism analysis, immunohistochemistry staining method, iodine I-124 girentuximab, laboratory biomarker analysis, pharmacological study, adjuvant therapy, neoadjuvant therapy, therapeutic conventional surgery
Drug · Genetic · Other + 1 more
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Jun 9, 2026, 11:44 PM EDT
Completed No phase listed Observational

Simulated Surgery Rehearsal (MIPN)

NCT03155295
View directory record Official record
Conditions
Nephrectomy
Interventions
Physical reality simulation, Virtual reality simulation
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jun 9, 2026, 11:44 PM EDT
Active, not recruiting Not applicable Interventional

Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer

NCT04922307
View directory record Official record
Conditions
Kidney Cancer
Interventions
Blood Sparing Protocol, Standard Blood Replacement
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Atlanta, Georgia • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jun 9, 2026, 11:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Kidney Donor Outcomes Cohort (KDOC) Study

NCT01427452
View directory record Official record
Conditions
Living Donor Nephrectomy
Interventions
Not listed
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
7
States / cities
Tucson, Arizona • Iowa City, Iowa • Portland, Maine + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Jun 9, 2026, 11:44 PM EDT
Active, not recruiting Not applicable Interventional

Use of Financial Incentives to Increase Live Kidney Donor Follow-up Compliance

NCT03090646
View directory record Official record
Conditions
Living Donors, Nephrectomy, Kidney
Interventions
Financial Incentive
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Jun 9, 2026, 11:44 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy

NCT03294109
View directory record Official record
Conditions
Pain, Postoperative, Analgesics, Opioid, Analgesics, Non-Narcotic, Physiological Effects of Drugs, Peripheral Nervous System Agents, Patient Satisfaction, Return to Work, Activity, Sexual
Interventions
Abdominal wall block with liposomal bupivicaine
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Jun 9, 2026, 11:44 PM EDT
Completed Not applicable Interventional Results available

Off Clamp Randomization

NCT01732120
View directory record Official record
Conditions
Renal Cancer, Renal Ischemia
Interventions
Off-clamp partial nephrectomy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jun 9, 2026, 11:44 PM EDT
Terminated Not applicable Interventional Results available

Microwave Coagulation in Partial Nephrectomy Protocol

NCT01931462
View directory record Official record
Conditions
Cancer of Kidney
Interventions
Microwave pre-coagulation
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 25, 2018 · Synced Jun 9, 2026, 11:44 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy

NCT06886087
View directory record Official record
Conditions
Living Kidney Donation, Hypertension, Nephrectomy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 9, 2026, 11:44 PM EDT
Completed Phase 4 Interventional Results available

Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy

NCT00765232
View directory record Official record
Conditions
Nephrectomy, Laparoscopic Donor Nephrectomy
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 26, 2012 · Synced Jun 9, 2026, 11:44 PM EDT
Recruiting Phase 2 Interventional

Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus

NCT05319015
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
Neoadjuvant Lenvatinib, Neoadjuvant Pembrolizumab, Radical nephrectomy, IVC thrombectomy, retroperitoneal lymph node dissection, Adjuvant Pembrolizumab
Drug · Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jun 9, 2026, 11:44 PM EDT
Active, not recruiting Not applicable Interventional

Pilot Study of an mHealth Intervention for Living Donor Follow-up

NCT03400085
View directory record Official record
Conditions
Living Donors, Nephrectomy, Kidney
Interventions
mHealth application
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Nashville, Tennessee • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Jun 9, 2026, 11:44 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy

NCT03024996
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
Atezolizumab, Placebo
Drug · Other
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
778 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
45
States / cities
Scottsdale, Arizona • Duarte, California • Lancaster, California + 37 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Jun 9, 2026, 11:44 PM EDT
Completed Not applicable Interventional

Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

NCT03581539
View directory record Official record
Conditions
Nephrectomy
Interventions
Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Jun 9, 2026, 11:44 PM EDT
Active, not recruiting Phase 2 Interventional

Prior Axitinib as a Determinant of Outcome of Renal Surgery

NCT03438708
View directory record Official record
Conditions
Clear Cell Renal Cell Carcinoma
Interventions
Axitinib Oral Tablet [Inlyta]
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
La Jolla, California • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jun 9, 2026, 11:44 PM EDT