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Showing 1–24 of 247 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nephrolithiasis Clear all
Completed Not applicable Interventional

Effect of Sodium Thiosulfate on Urine Chemistries of Hypercalciuric Stone Formers

NCT01088555
View directory record Official record
Conditions
Kidney Stones
Interventions
Sodium thiosulfate
Drug
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2013 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Not applicable Interventional Results available

Trial Comparing Three Different Devices for Kidney Stone Removal During Percutaneous Surgery

NCT00952315
View directory record Official record
Conditions
Kidney Stones
Interventions
Cyberwand, Stonebreaker, Lithoclast Select
Device
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
8
States / cities
Phoenix, Arizona • Chicago, Illinois • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Phase 4 Interventional Results available

Study of Tomography of Nephrolithiasis Evaluation

NCT01451931
View directory record Official record
Conditions
Urolithiasis
Interventions
Point-of-care Ultrasound, Radiology Ultrasound, Radiology CT
Other · Radiation
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
2,776 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
15
States / cities
Fresno, California • Sacramento, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

NCT00587041
View directory record Official record
Conditions
Nephrolithiasis, Hyperoxaluria, Crohn's Disease
Interventions
Oxadrop, Agri-King Synbiotic (AKSB), Placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 30, 2012 · Synced Sep 5, 2026, 1:31 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis

NCT01127854
View directory record Official record
Conditions
Kidney Stones, Urolithiasis, Calcium Oxalate Urolithiasis
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 5, 2026, 1:31 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi

NCT05869890
View directory record Official record
Conditions
Renal Calculi
Interventions
MOSES laser system
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Not applicable Interventional

Nephrolithiasis and Bariatric Surgery

NCT00169793
View directory record Official record
Conditions
Obesity, Nephrolithiasis
Interventions
evaluation of kidney stone risk after bariatric surgery, Evaluate risk of kidney stones after bariatric surgery
Other
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Sep 5, 2026, 1:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy

NCT06149455
View directory record Official record
Conditions
Infections, Urinary Tract, Nephrolithiasis
Interventions
Duration of antibiotics
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Sep 5, 2026, 1:31 PM EDT
Recruiting No phase listed Observational

Monogenic Kidney Stone - Genetic Testing

NCT03305835
View directory record Official record
Conditions
Rare Kidney Stone Diseases
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 5, 2026, 1:31 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

NCT06635889
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Bupivacaine, Normal saline
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 5, 2026, 1:31 PM EDT
Withdrawn Not applicable Interventional

Long Pulse Versus Short Pulse Laser Dusting for Renal Stones

NCT03608098
View directory record Official record
Conditions
Kidney Stone, Ureter Stone, Renal Stone
Interventions
Short Pulse Duration, Long Pulse Duration
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 5, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease

NCT06210009
View directory record Official record
Conditions
Kidney Stone
Interventions
DASH-Style Diet, Western-Style Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Phase 3 Interventional

Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi

NCT00177086
View directory record Official record
Conditions
Kidney Calculi, Ureteral Calculi, Colic
Interventions
Alfuzosin Hydrochloride
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 5, 2026, 1:31 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Alfuzosin for Medical Expulsion Therapy of Ureteral Stones

NCT00713739
View directory record Official record
Conditions
Kidney Stones
Interventions
Alfuzosin, nifedipine, doxazosin, prazosin
Drug
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2012 · Synced Sep 5, 2026, 1:31 PM EDT
Terminated Phase 3 Interventional

Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

NCT03847090
View directory record Official record
Conditions
Enteric Hyperoxaluria
Interventions
Reloxaliase, Placebo
Drug
Lead sponsor
Allena Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
64
States / cities
Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Sep 5, 2026, 1:31 PM EDT
Completed No phase listed Observational

Fluid Intake Application to Reduce Kidney Stone Risks

NCT01928108
View directory record Official record
Conditions
Kidney Stone
Interventions
iPhone Application, Android Application
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Not applicable Interventional

Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control

NCT02224287
View directory record Official record
Conditions
Urolithiasis, Kidney Stones
Interventions
Technologist control of fluoroscopy, Surgeon control of fluoroscopy
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
5 Years to 25 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2020 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Perioperative Pregabalin in Ureteroscopy

NCT04122196
View directory record Official record
Conditions
Kidney Stone, Pain, Postoperative, Addiction, Opioid Use
Interventions
Pregabalin 300mg, Placebo oral tablet
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Not applicable Interventional

Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney

NCT02210650
View directory record Official record
Conditions
Ureteral Stones, Kidney Stones
Interventions
Symptomatic stone removal, Asymptomatic kidney stones and ureteral stone removed
Procedure
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
4
States / cities
Indianapolis, Indiana • Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 5, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate and Citrate

NCT05334979
View directory record Official record
Conditions
Kidney Stone, Normal Controls
Interventions
Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Phase 4 Interventional Results available

Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

NCT05082142
View directory record Official record
Conditions
Kidney Calculi, Urologic Diseases, Benign Prostatic Hypertrophy
Interventions
Tranexamic acid
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years · Male only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 5, 2026, 1:31 PM EDT
Completed Not applicable Interventional Results available

ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi

NCT03959683
View directory record Official record
Conditions
Kidney Calculi
Interventions
Trilogy Lithotrite, The ShockPulse-SE Lithotripsy System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Phoenix, Arizona • Indianapolis, Indiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 5, 2026, 1:31 PM EDT
Terminated Not applicable Interventional

Validation of Low Dose CT for Diagnosis of Urolithiasis

NCT03656913
View directory record Official record
Conditions
Nephrolithiasis, Ureterolithiases
Interventions
Extremely low dose CT
Diagnostic Test
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
4 Years to 20 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Sep 5, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Tract Closure in PCNL

NCT07668817
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Floseal, Surgicel, Surgiflo, Balloon Tamponade
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 5, 2026, 1:31 PM EDT