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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nephrolithotomy Clear all
Terminated Not applicable Interventional

Comparing Previously Placed Nephrostomy Tract (NT) Versus Single Stage Percutaneous Nephrolithotomy (PCNL)

NCT00907946
View directory record Official record
Conditions
Urolithiasis
Interventions
NT 1 day before PCNL
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Jun 26, 2026, 1:02 PM EDT
Active, not recruiting No phase listed Observational

Reducing Opioid Prescription After Kidney Stone Removal Surgery

NCT05353478
View directory record Official record
Conditions
Kidney Stone
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

NCT02579161
View directory record Official record
Conditions
Kidney Stones
Interventions
cephalosporins, Fluoroquinolones, Clindamycin, Ampicillin/Gentamicin
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
2
States / cities
Manhasset, New York • New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jun 26, 2026, 1:02 PM EDT
Not listed Not applicable Interventional

Ambulatory Versus Inpatient Percutaneous Nephrolithotomy

NCT04690010
View directory record Official record
Conditions
Kidney Calculi
Interventions
Ambulatory tubeless PCNL, Inpatient PCNL with nephrostomy tube
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional

MIP Versus PCNL for Kidney Stone Disease

NCT04767919
View directory record Official record
Conditions
Kidney Stone
Interventions
Standard Percutaneous Nephrolithotomy (sPCNL), Minimally Invasive Percutaneous Nephrolithotomy (MIP)
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Terminated Phase 4 Interventional

Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy

NCT04663269
View directory record Official record
Conditions
Kidney Stone, Surgery
Interventions
4mg PF Dexamethasone, Control Test
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Jun 26, 2026, 1:02 PM EDT
Active, not recruiting No phase listed Observational

Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones

NCT06922006
View directory record Official record
Conditions
Kidney Stones
Interventions
Percutaneus nephrolithotomy (PCNL)
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Phase 4 Interventional

Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment

NCT03229889
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Cialis 5Mg Tablet, Flomax 0.4Mg Capsule, Cialis + Flomax, Placebo
Drug · Combination Product
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 99 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Completed No phase listed Observational

Simulated Rehearsal for Percutaneous Nephrolithotomy

NCT03272529
View directory record Official record
Conditions
Nephrolithotomy
Interventions
Patient-specific simulated rehearsals, Idealized simulated rehearsals, Standard simulation
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jun 26, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

NCT05024344
View directory record Official record
Conditions
Nephrolithotomy, Percutaneous
Interventions
Erector Spinae Plane Block, Ropivacaine 0.5% Injectable Solution, Dexamethasone
Procedure · Drug
Lead sponsor
University of Tennessee Medical Center
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis

NCT05993546
View directory record Official record
Conditions
Kidney Stone
Interventions
vacuum assisted sheath, passive suction via conventional sheath
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Standard vs Mini-PCNL for the Treatment of Stone Disease

NCT04069013
View directory record Official record
Conditions
Urolithiasis, Kidney Stone, Kidney Calculi, Ureteral Calculi, Kidney Diseases
Interventions
PCNL
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Not yet recruiting Not applicable Interventional

The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy

NCT07211555
View directory record Official record
Conditions
Renal Stone Disease, Kidney Calculi, Refractory Kidney Stones, Kidney Stones
Interventions
LARC Robotic System (Micromate™ Version 3.0)
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy

NCT04556396
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Cone beam CT
Diagnostic Test
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Jun 26, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Tract Closure in PCNL

NCT07668817
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Floseal, Surgicel, Surgiflo, Balloon Tamponade
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Occlusion Balloon vs. 5FR Ureteral Catheter

NCT06798753
View directory record Official record
Conditions
Kidney Stones
Interventions
Occlusion Balloon Catheter, 5FR Ureteral Catheter
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS

NCT07072598
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis, Urolithiasis
Interventions
ClearPETRA suction access sheath
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])

NCT02384200
View directory record Official record
Conditions
Nephrolithiasis, Urinary Tract Infections
Interventions
nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin, vancomycin, ceftriaxone
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
7
States / cities
Phoenix, Arizona • San Diego, California • San Francisco, California + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Phase 4 Interventional

Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy

NCT05121168
View directory record Official record
Conditions
Pain, Acute Postoperative, Renal Stone
Interventions
Active bupivacaine 0.25% via an erector spinae plane perineural catheter, Placebo normal saline via an erector spinae plane perineural catheter
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Phase 3 Interventional

Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL

NCT01548196
View directory record Official record
Conditions
Nephrolithotomy
Interventions
Standard Percutaneous nephrolithotomy
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones

NCT04597619
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Novel Nonopioid Pathway
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 24, 2023 · Synced Jun 26, 2026, 1:02 PM EDT
Completed No phase listed Observational

Radiation Dose of Pediatric Patients During Ureteroscopy

NCT02895711
View directory record Official record
Conditions
Urolithiasis
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
0 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2022 · Synced Jun 26, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones

NCT05835323
View directory record Official record
Conditions
Kidney Calculi
Interventions
Robotic-assisted mini-PCNL
Device
Lead sponsor
Auris Health, Inc.
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jun 26, 2026, 1:02 PM EDT
Not listed Not applicable Interventional

Paravertebral Block for Percutaneous Nephrolithotomy

NCT01480102
View directory record Official record
Conditions
Post Operative Pain
Interventions
Group A-Paravertebral block, Group B- No block
Drug · Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Jun 26, 2026, 1:02 PM EDT