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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:56 AM EDT

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Showing 145–168 of 28,667 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Nervous System Diseases Clear all
Withdrawn Phase 3 Interventional

Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain

NCT02311777
View directory record Official record
Conditions
Phantom Pain
Interventions
Pregabalin, Ketamine, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 5, 2026, 4:56 AM EDT
Completed No phase listed Observational

Responsiveness to Dalfampridine-ER Treatment Among Multiple Sclerosis Patients

NCT01399957
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Not listed
Lead sponsor
Mount Sinai Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 10, 2015 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

We-PAP: A Couples-based Intervention for Sleep Apnea

NCT04759157
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Couples-based treatment, Standardized education
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
50 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities

NCT03684512
View directory record Official record
Conditions
Adolescent Behavior, Intellectual Disability, Down Syndrome, Physical Activity
Interventions
Group Exercise Sessions, Individual Support Sessions, Facebook Group
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
10 Years to 21 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 5, 2026, 4:56 AM EDT
Recruiting Phase 1Phase 2 Interventional

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

NCT06161519
View directory record Official record
Conditions
Glioma, Medulloblastoma, Ependymoma, Glioblastoma
Interventions
PLX038
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 5, 2026, 4:56 AM EDT
Terminated Phase 3 Interventional

An Open-Label Extension Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy

NCT03917719
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
Edasalonexent
Drug
Lead sponsor
Catabasis Pharmaceuticals
Industry
Eligibility
4 Years to 12 Years · Male only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
15
States / cities
Sacramento, California • Atlanta, Georgia • Iowa City, Iowa + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Oct 5, 2026, 4:56 AM EDT
Recruiting Not applicable Interventional

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

NCT05820919
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
Interventions
LOCK Sleep Program, No intervention (control period/baseline data collection)
Behavioral · Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years and older
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Lakewood, Colorado • Murfreesboro, Tennessee • San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Phase 2 Interventional Results available

RNS® System Feasibility Study

NCT00079781
View directory record Official record
Conditions
Epilepsy
Interventions
RNS® System implantation, RNS® System responsive stimulation
Procedure · Device
Lead sponsor
NeuroPace
Industry
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
12
States / cities
Phoenix, Arizona • New Haven, Connecticut • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Oct 5, 2026, 4:56 AM EDT
Not listed Not applicable Interventional

Effect of an Amino-Acid-Based Blend on Human Growth Hormone (hGH) and Fibromyalgia (FM) Symptoms

NCT04510181
View directory record Official record
Conditions
Fibromyalgia
Interventions
amino acid-based blend
Dietary Supplement
Lead sponsor
Pekarovics, Susan, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Phase 3 Interventional Results available

Study of Oral Fampridine-SR in Multiple Sclerosis

NCT00127530
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Fampridine-SR, Placebo
Drug
Lead sponsor
Acorda Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Phase 2 Interventional Results available

Study of Arimoclomol in Inclusion Body Myositis (IBM)

NCT02753530
View directory record Official record
Conditions
Inclusion Body Myositis
Interventions
Arimoclomol, Placebo
Drug · Other
Lead sponsor
ZevraDenmark
Industry
Eligibility
45 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
11
States / cities
Phoenix, Arizona • Irvine, California • Aurora, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 5, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Studying Childhood-Onset Hemidystonia

NCT01432899
View directory record Official record
Conditions
Dystonia, Cerebral Palsy
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
7 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 5, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Addressing Attitudes to Improve Use of Protective Headwear in Older Adults

NCT01582464
View directory record Official record
Conditions
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Interventions
Social Marketing for protective headgear
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Multiple, California
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Rapid Cadence Cycling for Parkinson's Disease: A Study of Implementation and Efficacy in the Community Setting

NCT03675932
View directory record Official record
Conditions
Parkinson Disease
Interventions
Rapid Cadence Cycling on a Solo-Rider Spin Bicycle
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 5, 2026, 4:56 AM EDT
Suspended Early Phase 1 Interventional

PBA Use for Treatment of ATF6-/- Patients

NCT04041232
View directory record Official record
Conditions
ACHROMATOPSIA 7, Achromatopsia
Interventions
PBA
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 5, 2026, 4:56 AM EDT
Terminated Phase 3 Interventional

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

NCT00031798
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Depression, Fatigue, Quality of Life
Interventions
methylphenidate hydrochloride, quality-of-life assessment, radiation therapy
Drug · Procedure · Radiation
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
7
States / cities
Phoenix, Arizona • Decatur, Illinois • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 5, 2026, 4:56 AM EDT
Recruiting Phase 2 Interventional

Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

NCT05303987
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Propofol sedation, Dexmedetomidine sedation
Drug
Lead sponsor
Erin Kirkham
Other
Eligibility
3 Years to 11 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?

NCT02987621
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
tDCS
Device
Lead sponsor
Colorado State University
Other
Eligibility
30 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 5, 2026, 4:56 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Balance and Energetics of Walking Using a Hip Exoskeleton

NCT05447884
View directory record Official record
Conditions
Stroke
Interventions
A zero impedance mode, controlling a wearable bilateral hip exoskeleton, A personalized optimal assistance mode, controlling a wearable bilateral hip exoskeleton, A free walking mode, without wearing a wearable bilateral hip exoskeleton
Other
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Oct 5, 2026, 4:56 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Smartphone Application to PREDICT Real-Time Cardiovascular Risk for Heart Attack and Stroke

NCT07735338
View directory record Official record
Conditions
Myocardial Infarction (MI), Stroke
Interventions
Smartphone application Antshrike
Device
Lead sponsor
Stanford University
Other
Eligibility
40 Years to 79 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Phase 2 Interventional Results available

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

NCT00024258
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Kidney Cancer, Liver Cancer, Neuroblastoma, Ovarian Cancer, Retinoblastoma, Sarcoma
Interventions
arsenic trioxide
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Up to 40 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Oct 5, 2026, 4:56 AM EDT
Recruiting Phase 2 Interventional

A Trial Investigating Lu AF28996 in Adults With Parkinson's Disease Who Have Motor Fluctuations

NCT07514858
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Lu AF28996, Placebo
Drug
Lead sponsor
H. Lundbeck A/S
Industry
Eligibility
40 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Farmington Hills, Michigan • Round Rock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 5, 2026, 4:56 AM EDT
Withdrawn No phase listed Observational

Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy

NCT01882855
View directory record Official record
Conditions
Cirrhosis, Hepatic Encephalopathy
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 5, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease

NCT03347955
View directory record Official record
Conditions
Parkinson Disease, Surgery
Interventions
Neural implantation group, Sham surgery
Procedure
Lead sponsor
University of Denver
Other
Eligibility
30 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1999
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 5, 2026, 4:56 AM EDT