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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:37 PM EST

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Showing 313–336 of 397 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neural Systems Clear all
Completed No phase listed Observational

Sleep-disordered Breathing in Infants With Myelomeningocele

NCT04251806
View directory record Official record
Conditions
Sleep-disordered Breathing, Myelomeningocele
Interventions
neonatal polysomnography, 2-year Bayley Exam, 2-year polysomnography
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
Up to 2 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
9
States / cities
Birmingham, Alabama • Aurora, Colorado • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder

NCT06025734
View directory record Official record
Conditions
Spina Bifida
Interventions
Transcutaneous Tibial Nerve Stimulation (TTNS) treatment
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

NCT07110376
View directory record Official record
Conditions
Parkinson Disease
Interventions
Nighttime Deep Brain Stimulation with Varying Amplitude Settings
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Active, not recruiting Not applicable Interventional

Behavioral and Neural Correlates of Post-Stroke Fatigue

NCT06088914
View directory record Official record
Conditions
Stroke, Fatigue
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional Results available

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia

NCT02669836
View directory record Official record
Conditions
Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I, Type I Arnold-Chiari Malformation, Syringomyelia
Interventions
Posterior fossa decompression, Dural Augmentation
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 21 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases

NCT05672849
View directory record Official record
Conditions
Neural Tube Defects
Interventions
Modified Surgical Instruments/Devices (Sheaths and Irrigator)
Device
Lead sponsor
Michael A Belfort
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans

NCT05996900
View directory record Official record
Conditions
Major Depressive Disorder, Epilepsy
Interventions
Intracranial electrodes, TMS
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Not yet recruiting Early Phase 1 Interventional

Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation

NCT07721272
View directory record Official record
Conditions
Epilepsy, Essential Tremor, Seizures, Memory Consolidation, Memory Disorders, Memory Replay, Memory Encoding, Cognitive Control, Motor Abilities
Interventions
Cobenfy KarXT pill (50/20 mg), Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Enrolling by invitation No phase listed Observational

Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease

NCT04566341
View directory record Official record
Conditions
Parkinson Disease, Parkinson
Interventions
OCT - TCE
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Active, not recruiting Not applicable Interventional

Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees

NCT06391697
View directory record Official record
Conditions
Amputation
Interventions
eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
View directory record Official record
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2005 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

Assessment of Neural Signals for the Control of Assistive Devices

NCT06533969
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Initial Encounter
Interventions
Epidural Spinal Cord Stimulation, Electrocorticographic, Electroencephalographic
Procedure · Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Completed Phase 2 Interventional

Mind and Body Approaches to Pain Reduction in Youth With Migraine

NCT03472092
View directory record Official record
Conditions
Headache, Migraine, Migraine, Migraine Disorders, Headache
Interventions
Cognitive Behavioral Therapy (CBT), Placebo, Amitriptyline, Biofeedback-Assisted Relaxation Training (BART), Cognitive Reappraisal Training (CR)
Behavioral · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 17 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional

An Early Feasibility Study of a Robotically Implanted Brain-Computer Interface for Neural Control of External Devices in Spinal Cord Injury, Amyotrophic Lateral Sclerosis, and Chronic Ischemic Stroke

NCT07929792
View directory record Official record
Conditions
Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Chronic Ischemic Stroke, Tetraplegia/Tetraparesis
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional Results available

Exercise and Parkinson's: Comparing Interventions and Exploring Neural Mechanisms

NCT01768832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Treadmill, Tango, Stretching
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
30 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional

Examining the Neural Effects of a Behavioral Intervention for Physical Activity in Multiple Sclerosis

NCT04496804
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 4, 2022 · Synced Nov 13, 2026, 2:37 PM EST
Terminated Not applicable Interventional

Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease

NCT02232958
View directory record Official record
Conditions
Encephalopathy, White Matter Hyperintensities, Impaired Oxygen Delivery
Interventions
Hyperbaric Oxygen Treatment
Other
Lead sponsor
St. Luke's Hospital, Chesterfield, Missouri
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Chesterfield, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional

A Wheelchair Propulsion Training Program

NCT04009187
View directory record Official record
Conditions
Spinal Cord Injuries, Multiple Sclerosis, Amputation, Spina Bifida
Interventions
In-person wheelchair propulsion training program, 30-minute education session
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Nov 13, 2026, 2:37 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Alternating Current Stimulation (tACS) in Aphasia

NCT04375722
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
tACS
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Not yet recruiting Not applicable Interventional

Parenting Program for Young Children With Spina Bifida

NCT07915557
View directory record Official record
Conditions
Spina Bifida
Interventions
Positive Parenting Program
Behavioral
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2029
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2026 · Synced Nov 13, 2026, 2:37 PM EST
Terminated Phase 3 Interventional Results available

Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits

NCT01000064
View directory record Official record
Conditions
Traumatic Brain Injury, Attention Deficit Disorder
Interventions
Vyvanse, fMRI, Placebo
Drug · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
16 Years to 45 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional

e-OPRA Implant System for Lower Limb Amputees

NCT03720171
View directory record Official record
Conditions
Amputation
Interventions
e-OPRA Implant System
Device
Lead sponsor
Integrum
Industry
Eligibility
22 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Nov 13, 2026, 2:37 PM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation

NCT06522685
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
Device
Lead sponsor
Morgan State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Nov 13, 2026, 2:37 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wide Diameter Bone Anchored Implant Study

NCT01671176
View directory record Official record
Conditions
Conductive Hearing Loss, Conductive and Sensori-neural Hearing Loss in the Same Ear, Unilateral, Profound Sensori-neural Hearing Loss
Interventions
Wide diameter bone anchored implant
Device
Lead sponsor
Oticon Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Sarasota, Florida • Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Nov 13, 2026, 2:37 PM EST