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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Neural Tube Defects (NTDs) Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies

NCT04738539
View directory record Official record
Conditions
Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic, Urologic Diseases, Neurologic Dysfunction
Interventions
Contrast Enhanced Voiding Urosonography with Urodynamic Testing, Urodynamic Testing
Drug · Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
Up to 18 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Jul 23, 2026, 7:07 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Virtual Peer Health Coaching for Adolescents With Disabilities

NCT05587634
View directory record Official record
Conditions
Cerebral Palsy, Spina Bifida
Interventions
Virtual Peer Health Coaching
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional Results available

Urological and Renal Disease Engaging Adolescents in Adherence Collaborative Trial

NCT03045276
View directory record Official record
Conditions
Spina Bifida, Kidney Transplant
Interventions
Behavioral Feedback and Economic Incentives: Arm 1, Behavioral Feedback and Economic Incentives: Arm 2
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 24 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
6
States / cities
Atlanta, Georgia • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 23, 2026, 7:07 AM EDT
Not listed Not applicable Interventional

Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation

NCT05581472
View directory record Official record
Conditions
Chronic Pain, Chiari Malformation
Interventions
Online Acceptance and Commitment Therapy Intervention + Phone Coaching, Online Acceptance and Commitment Therapy Intervention without phone coaching
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional

CIC Behavioral Economics in Children With Spina Bifida

NCT05562713
View directory record Official record
Conditions
Spina Bifida, Neurogenic Bladder
Interventions
Present Bias without Loss Aversion, Present Bias with Loss Aversion
Behavioral
Lead sponsor
Duke University
Other
Eligibility
4 Years to 12 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional Results available

Hemangioma Associated With High Rates of Morbidity

NCT00394888
View directory record Official record
Conditions
Hemangioma
Interventions
MRI, MRI of head and neck, Dermatological Examination, Cardiac examination, Abdominal ultrasound
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Up to 18 Years
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Jul 23, 2026, 7:07 AM EDT
Terminated No phase listed Observational

Automated Myocardial Performance Index Using Samsung HERA W10

NCT04140669
View directory record Official record
Conditions
Twin to Twin Transfusion Syndrome, Congenital Diaphragmatic Hernia, Neural Tube Defects, Lower Urinary Tract Infection
Interventions
Automated Myocardial Performance Index (MPI)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional

A Randomized Exercise Trial for Wheelchair Users

NCT00866112
View directory record Official record
Conditions
Spinal Cord Injury, Multiple Sclerosis, Muscular Dystrophy, Cerebral Palsy, Spina Bifida, Amputation, Arthritis, Stroke
Interventions
Educational session to promote physical activity, Minimal contact
Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Jul 23, 2026, 7:07 AM EDT
Recruiting Not applicable Interventional

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591
View directory record Official record
Conditions
Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jul 23, 2026, 7:07 AM EDT
Recruiting Not applicable Interventional

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

NCT03856034
View directory record Official record
Conditions
Neural Tube Defects, Spina Bifida, Myelomeningocele, Chiari Malformation
Interventions
Fetoscopy
Device
Lead sponsor
USFetus
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Wellington, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Phase 3 Interventional Results available

Duragen Versus Duraguard in Chiari Surgery

NCT00741858
View directory record Official record
Conditions
Chiari Malformation
Interventions
Duragen duraplasty, Duraguard duraplasty
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 12, 2015 · Synced Jul 23, 2026, 7:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Salt-FA to Increase Folate Levels

NCT06174883
View directory record Official record
Conditions
Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
Interventions
Folic acid fortified iodized salt
Dietary Supplement
Lead sponsor
Hydrocephalus and Neuroscience Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional Results available

Prevention of Post Operative Bone Loss in Children

NCT00655681
View directory record Official record
Conditions
Osteoporosis, Cerebral Palsy, Spina Bifida, Osteopenia, Osteogenesis Imperfecta
Interventions
pamidronate, saline
Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
4 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Phase 2 Interventional Results available

Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB

NCT02748356
View directory record Official record
Conditions
Lower Urinary Tract Symptoms
Interventions
Lactobacillus
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
6 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Jul 23, 2026, 7:07 AM EDT
Withdrawn Phase 2 Interventional

Efficacy of Acetaminophen in Posterior Fossa Surgery

NCT02532322
View directory record Official record
Conditions
Arnold-Chiari Malformation, Posterior Fossa Tumors
Interventions
IV acetaminophen, normal saline
Drug
Lead sponsor
Children's National Research Institute
Other
Eligibility
2 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Management of Myelomeningocele Study (MOMS)

NCT00060606
View directory record Official record
Conditions
Meningomyelocele, Spinal Dysraphism
Interventions
Prenatal Myelomeningocele Repair Surgery, Postnatal Myelomeningocele Repair Surgery
Procedure
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
18 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2017
U.S. locations
3
States / cities
San Francisco, California • Philadelphia, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Jul 23, 2026, 7:07 AM EDT
Recruiting No phase listed Observational

Fetoscopic Neural Tube Defect Repair

NCT06946563
View directory record Official record
Conditions
Neural Tube Defects, Spina Bifida
Interventions
Fetoscopic Neural Tube Defect Repair Devices
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Phase 2 Interventional Results available

Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB

NCT02748317
View directory record Official record
Conditions
Lower Urinary Tract Symptoms
Interventions
Lactobacillus rhamnosus GG
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jul 23, 2026, 7:07 AM EDT
Completed Phase 2 Interventional Results available

Post T-plant Infusion of Allogeneic Cytokine Induced Killer (CIK) Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorders

NCT01392989
View directory record Official record
Conditions
Neural Tube Defects, Anemia, Leukemia, Myeloid, Bone Marrow Transplant Failure, Myelodysplastic Syndromes (MDS), Myeloproliferative Disorders
Interventions
CIK cells, Cyclosporine, Mycophenolate Mofetil, Thymoglobulin, Total Lymphoid Irradiation (TLI)
Drug · Radiation
Lead sponsor
Everett Meyer
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Jul 23, 2026, 7:07 AM EDT
Terminated No phase listed Observational

Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH)

NCT02386228
View directory record Official record
Conditions
Intraventricular Hemorrhage, Spina Bifida
Interventions
collection of CSF and blood
Genetic
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
Up to 6 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Jul 23, 2026, 7:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Folate Metabolism in Normal Weight and Obese Women of Child-bearing Age

NCT01743196
View directory record Official record
Conditions
Obesity, Neural Tube Defects
Interventions
Not listed
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Jul 23, 2026, 7:07 AM EDT
Recruiting Phase 2Phase 3 Interventional

Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC

NCT05491525
View directory record Official record
Conditions
Neurogenic Detrusor Overactivity
Interventions
Vibegron
Drug
Lead sponsor
Urovant Sciences GmbH
Industry
Eligibility
2 Years to 17 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
11
States / cities
Little Rock, Arkansas • Orange, California • Aurora, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 23, 2026, 7:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

In-Utero Endoscopic Correction of Spina Bifida

NCT04362592
View directory record Official record
Conditions
Neural Tube Defects, Spina Bifida, Myelomeningocele
Interventions
In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique, In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 52 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2031
U.S. locations
2
States / cities
Los Angeles, California • Wellington, Florida
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 23, 2026, 7:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Folic Acid Salt Study (FISFA Zambia)

NCT06734611
View directory record Official record
Conditions
Folate Deficiency, Neural Tube Defects
Interventions
Fortified Iodized Salt with Folic Acid (FISFA)
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 23, 2026, 7:07 AM EDT