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ClinicalTrials.gov public records Last synced Oct 4, 2026, 7:39 AM EDT

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Showing 73–96 of 593 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neurological Impairment Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Peripheral Reading

NCT03640130
View directory record Official record
Conditions
Central Visual Impairment
Interventions
Gaze-contingent text enhancement
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
Not listed
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 4 Interventional

A fMRI(Functional Magnetic Resonance Imaging) Research Study to Learn More About Multiple Sclerosis and Individuals Potentially Experiencing Memory Difficulties

NCT00315367
View directory record Official record
Conditions
Relapsing-Remitting Multiple Sclerosis
Interventions
Donepezil HCI (drug)
Drug
Lead sponsor
Neurognostics
Industry
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 16, 2007 · Synced Oct 4, 2026, 7:39 AM EDT
Completed No phase listed Observational

Effects of Stimulus Validity on Speech Recognition

NCT00013364
View directory record Official record
Conditions
Hearing Impaired
Interventions
Talker variability
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 4 Interventional Results available

Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

NCT00526630
View directory record Official record
Conditions
Parkinson's Disease, Gait Impairment
Interventions
Methylphenidate (MPD), Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
35 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 22, 2015 · Synced Oct 4, 2026, 7:39 AM EDT
Not yet recruiting Early Phase 1 Interventional

Cholinergic Enhancement of Theta

NCT07228338
View directory record Official record
Conditions
Epilepsy, Seizures, Cognitive Impairment, Mild, Memory Disorder, Memory Loss
Interventions
COBENFY KarXT (50/20 mg), Control
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 2 Interventional

D-MPH in the Treatment of Fatigue and Neurobehavioral Function Related to Chemotherapy in Adult Cancer Patients

NCT00047476
View directory record Official record
Conditions
Fatigue, Neoplasms
Interventions
dexmethylphenidate(d-mph)
Drug
Lead sponsor
Celgene Corporation
Industry
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
21
States / cities
Birmingham, Alabama • Flagstaff, Arizona • Tucson, Arizona + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Results available

Problem Adaptation Therapy (PATH) vs. Supportive Therapy in Treating Depressed, Cognitively Impaired Older Adults

NCT00368940
View directory record Official record
Conditions
Depression
Interventions
PATH, ST-CI
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Auditory Training and Hearing Aid Satisfaction

NCT04230876
View directory record Official record
Conditions
Hearing Impairment, Sensorineural
Interventions
Auditory Brian Training Games/Activities
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Heat Exposure on Cognition in Persons With Tetraplegia

NCT02488824
View directory record Official record
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Warm Temperature
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 68 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 4, 2026, 7:39 AM EDT
Not yet recruiting Not applicable Interventional

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

NCT07417891
View directory record Official record
Conditions
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis, Mild Cognitive Impairment, MCI, Mild Cognitive Impairment (MCI), Dementia
Interventions
Well-formulated ketogenic diet
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
55 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fairway, Kansas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment

NCT03590327
View directory record Official record
Conditions
Apathy, Mild Cognitive Impairment, Transcranial Magnetic Stimulation, Loneliness, COVID, Neuropsychiatric Symptoms
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 2Phase 3 Interventional Results available

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

NCT01767909
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Insulin (Humulin® R U-100), Placebo
Drug
Lead sponsor
University of Southern California
Other
Eligibility
55 Years to 85 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
25
States / cities
Phoenix, Arizona • Irvine, California • New Haven, Connecticut + 18 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional

Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)

NCT02301247
View directory record Official record
Conditions
Multiple Sclerosis, Progressive, Cognition - Other, Memory Impairment
Interventions
Memory retraining exercises, Placebo control memory exercises
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
30 Years to 59 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 4, 2026, 7:39 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

NCT05907343
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Dementia (AD)
Interventions
Closed-loop TBS, Open-loop TBS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Recruiting No phase listed Observational

Sinus Disease in Young Children With Cystic Fibrosis

NCT06191640
View directory record Official record
Conditions
Cystic Fibrosis in Children, Cystic Fibrosis, Chronic Rhinosinusitis (Diagnosis), Olfactory Disorder, Olfactory Impairment
Interventions
Ivacaftor or elexacaftor/tezacaftor/ivacaftor
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
2 Years to 8 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
Aurora, Colorado • Iowa City, Iowa • Kansas City, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints

NCT02433691
View directory record Official record
Conditions
Memory Impairment
Interventions
simultaneous aerobic exercise, sequential aerobic exercise, stretching and toning
Other
Lead sponsor
David Merrill, MD, PhD
Other
Eligibility
60 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 4, 2026, 7:39 AM EDT
Not yet recruiting Not applicable Interventional

Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss

NCT07216924
View directory record Official record
Conditions
Macular Degeneration, Central Visual Impairment
Interventions
Personalised Remapping Training, RSVP personalized remappi, Reading text in the wild with remapping
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 4, 2026, 7:39 AM EDT
Completed No phase listed Observational

MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care

NCT00400062
View directory record Official record
Conditions
Delirium, Aging, Dementia
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
3
States / cities
Nashville, Tennessee • Salt Lake City, Utah • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Audiobooks for Hearing Loss App as Auditory Training

NCT04231396
View directory record Official record
Conditions
Hearing Loss, Hearing Impaired Children, Hearing Impairment
Interventions
Audiobooks for hearing loss App
Other
Lead sponsor
BioSpeech
Industry
Eligibility
9 Years to 90 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Results available

Visuomotor Rehabilitation Training for Manual Task Deficits From Macular Scotomas

NCT01691027
View directory record Official record
Conditions
Scotoma, Central, Central Visual Impairment
Interventions
Visuo-motor training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 95 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

NCT00920647
View directory record Official record
Conditions
Hunter Syndrome
Interventions
Control, Idursulfase IT (1 mg), Idursulfase IT (10 mg), Idursulfase IT (30 mg)
Other · Drug
Lead sponsor
Shire
Industry
Eligibility
3 Years to 18 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional

Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone

NCT05746390
View directory record Official record
Conditions
Cognitive Impairment, Dementia, Memory Loss
Interventions
Home Alone
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
55 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Acupuncture on Anxiety and Working Memory

NCT01492738
View directory record Official record
Conditions
Memory Impairment, Anxiety
Interventions
Acupuncture
Procedure
Lead sponsor
National University of Health Sciences
Other
Eligibility
18 Years to 30 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
2
States / cities
Chicago, Illinois • Wilmette, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 4, 2026, 7:39 AM EDT
Completed Phase 2 Interventional

Measurement and Prediction of Outcomes of Amplification

NCT00013416
View directory record Official record
Conditions
Hearing Impaired
Interventions
Hearing
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 4, 2026, 7:39 AM EDT