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ClinicalTrials.gov public records Last synced Oct 7, 2026, 6:11 AM EDT

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Showing 121–144 of 593 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neurological Impairment Clear all
Completed No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)

NCT00908999
View directory record Official record
Conditions
Anosognosia, Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2011 · Synced Oct 7, 2026, 6:11 AM EDT
Terminated Not applicable Interventional

Exercise and Learning and Memory in Multiple Sclerosis

NCT03319771
View directory record Official record
Conditions
Multiple Sclerosis, Physical Activity, Memory Impairment, Cognitive Change
Interventions
Treadmill Walking Exercise Training, Stretching-and-toning Exercise Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 54 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 7, 2026, 6:11 AM EDT
Terminated Not applicable Interventional Results available

Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors

NCT01749800
View directory record Official record
Conditions
TBI, Attention Deficits, Motor Impairments
Interventions
GVS, Sham GVS, Armeo Spring
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)

NCT00109564
View directory record Official record
Conditions
Age-Related Memory Disorders
Interventions
ispronicline (nicotinic acetylcholine receptor agonist)
Drug
Lead sponsor
Targacept Inc.
Industry
Eligibility
50 Years to 80 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
15
States / cities
Mesa, Arizona • Peoria, Arizona • Denver, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2008 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional Results available

Progressive Intervention Program for Tinnitus Management

NCT00371436
View directory record Official record
Conditions
Hearing Loss, Tinnitus
Interventions
Progressive Audiologic Tinnitus Management, Usual Care
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Tampa, Florida • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Oct 7, 2026, 6:11 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Providing Access to the Visual Environment

NCT00341744
View directory record Official record
Conditions
Vision Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
3 Years to 21 Years
Enrollment
795 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sedative-Anxiolytic Effects on Simulated Driving Performance

NCT03297944
View directory record Official record
Conditions
Psychomotor Impairment
Interventions
Alprazolam 2mg (2ALP/PLC), Alprazolam 1mg (1ALP/PLC), Alprazolam 0.5mg (0.5ALP/PLC), Zolpidem 10mg (ZOL/PLC), Placebo (PLC/PLC), Alprazolam 1mg (PLC/ALC)
Drug
Lead sponsor
Marion Coe
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 7, 2026, 6:11 AM EDT
Active, not recruiting No phase listed Observational

Obi Medical Robot: Evaluating Effectiveness Related to Usability

NCT07151950
View directory record Official record
Conditions
Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
Interventions
One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
Device
Lead sponsor
Desin LLC
Industry
Eligibility
5 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Echolocation Aids Using Parametric Sound

NCT07218991
View directory record Official record
Conditions
Low Vision
Interventions
Wearable Echolocation Device
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Enrolling by invitation Not applicable Interventional

Research Study for Patients With Neurological Diseases Which Evaluates the Patient Experience of the MemorEM Device

NCT07222605
View directory record Official record
Conditions
Alzheimer Disease, Parkinson Disease, Frontotemporal Dementia, Cortico Basal Degeneration, Posterior Cortical Atrophy (PCA), Neurological Diseases or Conditions, Dementia
Interventions
MemorEM
Device
Lead sponsor
eQ8Health Corporation d/b/a CareONE Concierge
Industry
Eligibility
45 Years to 100 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

NCT05881239
View directory record Official record
Conditions
Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
Interventions
AROMHA Brain Health Test
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

NCT00920647
View directory record Official record
Conditions
Hunter Syndrome
Interventions
Control, Idursulfase IT (1 mg), Idursulfase IT (10 mg), Idursulfase IT (30 mg)
Other · Drug
Lead sponsor
Shire
Industry
Eligibility
3 Years to 18 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 7, 2026, 6:11 AM EDT
Completed No phase listed Observational

Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts

NCT00023036
View directory record Official record
Conditions
Sensorineural Hearing Loss, Cytomegalovirus Infection
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
Up to 99 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment

NCT03590327
View directory record Official record
Conditions
Apathy, Mild Cognitive Impairment, Transcranial Magnetic Stimulation, Loneliness, COVID, Neuropsychiatric Symptoms
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stanford ICU Delirium PIPRA Study

NCT06519890
View directory record Official record
Conditions
Delirium, Cognitive Impairment, Delirium, Postoperative
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Phase 1 Interventional

Visual Cortex Stimulation in Patients With Amblyopia

NCT00097162
View directory record Official record
Conditions
Amblyopia, Anisometropic Ambyopia, Amblyopia, Suppression
Interventions
Anodal stimulation
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 26, 2006 · Synced Oct 7, 2026, 6:11 AM EDT
Recruiting Not applicable Interventional

VR-Based Cognitive Stimulation Games for Delirium Prevention

NCT07641153
View directory record Official record
Conditions
Surgery, Delirium - Postoperative, Delirium
Interventions
Virtual Reality Software, Virtual Reality movies, Nurse led control arm
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
Up to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional

Effect of Activity on Sleep of Cognitively-Impaired Veterans

NCT00013182
View directory record Official record
Conditions
Alzheimer's Disease, Sleep Disorders
Interventions
social activity
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
55 Years and older · Male only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2001
U.S. locations
1
States / cities
No. Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 7, 2026, 6:11 AM EDT
Recruiting Phase 1Phase 2 Interventional

Valproate for the Treatment of Residual Amblyopia

NCT07226141
View directory record Official record
Conditions
Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
Interventions
Valproate, Placebo, Patch
Drug · Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Can Early Initiation of Rehabilitation With Wearable Sensor Technology Improve Outcomes in mTBI?

NCT03479541
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Balance; Distorted, Gait, Unsteady, Quality of Life, Veterans
Interventions
Timing of Rehabilitation, Biofeedback
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Early Phase 1 Interventional Results available

Caffeine and Neurologic Recovery Following Surgery and General Anesthesia

NCT03577730
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Caffeine Citrate, Dextrose Water
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 7, 2026, 6:11 AM EDT
Completed Not applicable Interventional

e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems

NCT00182832
View directory record Official record
Conditions
Cognitive Impairment, Delirium
Interventions
e-CHAMP (Enhancing Care for Hospitalized Older Adults with Cognitive Impairment), Standard Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Oct 7, 2026, 6:11 AM EDT
Not listed No phase listed Observational

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey

NCT06025877
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline, Cognitive Impairment, Memory Impairment
Interventions
PrecivityAD2(TM) blood test
Other
Lead sponsor
C2N Diagnostics
Industry
Eligibility
55 Years and older
Enrollment
400 participants
Timeline
2023 – 2025
U.S. locations
9
States / cities
San Francisco, California • Santa Monica, California • Park Ridge, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 7, 2026, 6:11 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peripheral Reading

NCT03640130
View directory record Official record
Conditions
Central Visual Impairment
Interventions
Gaze-contingent text enhancement
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
Not listed
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 7, 2026, 6:11 AM EDT