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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:01 AM EDT

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Showing 97–120 of 167 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neuronal Plasticity Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Walking Adaptability Post-Spinal Cord Injury

NCT01851629
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Brown Sequard Syndrome
Interventions
Locomotor Training, Cross-Sectional Testing (No Intervention)
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
4
States / cities
Gainesville, Florida • Jacksonville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2015 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games

NCT01115283
View directory record Official record
Conditions
Amblyopia
Interventions
Perceptual learning, Video Games, Occlusion therapy
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
5 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Computerized Memory Enhancing Treatment in MCI

NCT05332522
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neuroplasticity-based Computerized Cognitive Remediation
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
55 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of Acute Topical and Aromatic Essential Oil-Based Products for Cognitive Support

NCT07623811
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Cognitive Support System
Other
Lead sponsor
dōTERRA International
Industry
Eligibility
18 Years to 64 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Pleasant Grove, Utah
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 18, 2026, 2:01 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity

NCT04221256
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Administration of SSRI escitalopram, Paired Associative stimulation, Administration of Placebo
Drug · Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 18, 2026, 2:01 AM EDT
Completed No phase listed Observational

Hand Exercise and Upper Arm Anesthesia to Improvements Hand Function in Chronic Stroke Patients

NCT00006414
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 18, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional

Neurostimulation for Respiratory Function After Spinal Cord Injury

NCT05756894
View directory record Official record
Conditions
Spinal Cord Injuries, Cervical Spinal Cord Injury, Respiratory Function Impaired
Interventions
Neurostimulation, Repiratory training
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 18, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroplasticity in Parkinson's Disease

NCT05286736
View directory record Official record
Conditions
Parkinson, Parkinson Disease
Interventions
Neuroimaging, Quantitative assessments
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 18, 2026, 2:01 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers

NCT01172509
View directory record Official record
Conditions
Autism
Interventions
R-baclofen
Drug
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
18 Years to 30 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2015 · Synced Oct 18, 2026, 2:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury

NCT06101199
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Acute Intermittent Hypercapnic Hypoxia, Transcutaneous spinal cord stimulation, SHAM Acute Intermittent Hypercapnic Hypoxia, SHAM Transcutaneous spinal cord stimulation
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 18, 2026, 2:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Neural Substrates Underlying Adaptations in Manual Dexterity of Older Adults

NCT07011160
View directory record Official record
Conditions
Aging Hands
Interventions
Transcutaneous electrical nerve stimulation (TENS), Familiarization
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
54 Years to 89 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Chronic Pain Treatment With Enhanced Neuroplastic Responsiveness

NCT02681081
View directory record Official record
Conditions
Pain, Osteoarthritis
Interventions
Glucose Administration, Intermittent Fasting, Control
Other
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 85 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 18, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Stability of Motor Output in Aging Adults

NCT00970736
View directory record Official record
Conditions
Swallowing
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Oct 18, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spinal Cord Stimulation and Training

NCT05472584
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Electrophysiology assessment - spinal motoneuron, Activity-based training, Transcutaneous spinal cord stimulation
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Cognitive Training for the Prevention of Postoperative Delirium

NCT02963961
View directory record Official record
Conditions
Delirium
Interventions
Preoperative Cognitive Training Battery
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Oct 18, 2026, 2:01 AM EDT
Not yet recruiting Early Phase 1 Interventional

Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101

NCT07785102
View directory record Official record
Conditions
Major Depression
Interventions
TMS, NRX-101
Device · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Neurofeedback Technology (GZNT) for Persistent Post-Concussive Symptoms in Soldiers

NCT02509689
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Global Z-Score Neurofeedback Training
Behavioral
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Fort Carson, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Plantarflexor PAS - Stroke

NCT04515407
View directory record Official record
Conditions
Stroke, Hemiparesis, Gait Dysfunction
Interventions
PAS at Rest, PAS - Active, PAS - Walking
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 18, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

NCT05492188
View directory record Official record
Conditions
Spinal Cord Injuries, Neuropathic Pain, Neurological Injury, Pain
Interventions
Operant Conditioning of Cutaneous Reflexes
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Molecular Markers of Neuroplasticity During Exercise in People With Incomplete Spinal Cord Injury

NCT01538693
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
escitalopram oxalate, Cyproheptadine, sugar pill, Graded intensity exercise
Drug · Other
Lead sponsor
T. George Hornby
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 19, 2015 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Overcoming Learned Non-Use in Chronic Aphasia

NCT02012374
View directory record Official record
Conditions
Stroke-induced Aphasia
Interventions
Intensive Language Action Therapy
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Exercises for Synaptic Plasticity

NCT03058055
View directory record Official record
Conditions
Cognitive Change
Interventions
Placebo, Origami, Reading
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
65 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Oct 18, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1

NCT03896425
View directory record Official record
Conditions
Transcranial Direct Current Stimulation, Healthy
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 18, 2026, 2:01 AM EDT
Recruiting Phase 2 Interventional

Mindfulness-based Psilocybin Therapy for PTSD

NCT07104916
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
Interventions
Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only
Combination Product
Lead sponsor
Anthony P King
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 18, 2026, 2:01 AM EDT