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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Neuroscience Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Using Neuroscience to Optimize Digital Health Interventions Across Adulthood

NCT03744052
View directory record Official record
Conditions
Healthy
Interventions
Motivational Messages
Other
Lead sponsor
Duke University
Other
Eligibility
30 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Recruiting Not applicable Interventional

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

NCT07715591
View directory record Official record
Conditions
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Interventions
Music and Guided Imagery, Control, Music Only
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Twin Hearts Meditation on Mood, Cognitive Functioning, and EEG Dynamics

NCT07005830
View directory record Official record
Conditions
Positive Mood States, Negative Mood States, Cognitive Processing Speed, Cognitive Flexibility
Interventions
Twin Hearts Meditation
Behavioral
Lead sponsor
NeuroMeditation Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology

NCT03674398
View directory record Official record
Conditions
Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury, MTBI - Mild Traumatic Brain Injury, Acquired Brain Injury, Closed Head Injury
Interventions
Exercise+CT, Exercise only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 10, 2026, 11:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Duke Conte Center for the Neuroscience of Depression in Late Life

NCT00576875
View directory record Official record
Conditions
Major Depression
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
795 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2012 · Synced Sep 10, 2026, 11:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Craving & Decision-Making

NCT06440577
View directory record Official record
Conditions
Decision Making
Interventions
Audio-visual stimuli (Neutral-Relaxing), Audio-visual stimuli (Drug), Audio-visual stimuli (Non-Food), Audio-visual stimuli (Food)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 10, 2026, 11:02 PM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

NCT03610763
View directory record Official record
Conditions
Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
Interventions
Transcranial Direct Current Stimulation, Modified Constraint Induced Movement Therapy
Device · Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
3
States / cities
Louisville, Kentucky • Columbia, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 10, 2026, 11:02 PM EDT
Active, not recruiting Phase 3 Interventional

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

NCT06700343
View directory record Official record
Conditions
Relapsing-remitting Multiple Sclerosis (RRMS)
Interventions
Ocrelizumab (US), Ocrelizumab (EU), ABP 692
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 99 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
27
States / cities
Mobile, Alabama • Scottsdale, Arizona • Carlsbad, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Pain Neuroscience Education in a Spanish-Speaking Population

NCT03785353
View directory record Official record
Conditions
Pain, Educational Problems
Interventions
PNE lecture
Behavioral
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders

NCT03732248
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence
Interventions
Rapamycin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Behavioral Memory Modulation in Nicotine Addiction

NCT03744559
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
Retrieval Extinction Training (RET), Control Retrieval Extinction Training (RET)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
25 Years to 65 Years
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 10, 2026, 11:02 PM EDT
Terminated Not applicable Interventional

Using the Neuroscience of Fear Extinction for Anxiety Reduction

NCT03465137
View directory record Official record
Conditions
Social Anxiety
Interventions
Coordinated Anxiety Learning and Management (CALM)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Withdrawn No phase listed Observational

Brain-imaging and Adolescent Neuroscience Consortium

NCT01511679
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2013 · Synced Sep 10, 2026, 11:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

UCLA Fitness and Memory Study of Activity In Mild Cognitive Impairment (AIM)

NCT02001441
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 89 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Phase 4 Interventional Results available

Dynamics of Inflammation and Its Blockade on Motivational Circuitry in Depression

NCT03006393
View directory record Official record
Conditions
Depression
Interventions
Infliximab, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Phase 2 Interventional Results available

Enhancing Self Regulation Among Smokers

NCT04161144
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
Interventions
sirolimus, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 10, 2026, 11:02 PM EDT
Completed No phase listed Observational

PNE Delivered With a VR Headset in Outpatient LBP Patients

NCT04777877
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain Neuroscience Education delivered via a Virtual Reality Headset
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional

Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence

NCT06442306
View directory record Official record
Conditions
Chronic Pain, Opioid Dependence
Interventions
Pain Neuroscience Education, General Health Education
Other
Lead sponsor
Wichita State University
Other
Eligibility
18 Years to 95 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Chronic Depression and PTSD in Stroke Patients Admitted to the Neuroscience Intensive Care Unit (NICU) and Their Family Caregivers

NCT02797509
View directory record Official record
Conditions
Neurological Disorder
Interventions
Psychosocial Skills-Based Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 10, 2026, 11:02 PM EDT
Completed No phase listed Observational

Contemporary Pain Science Education and Physician Assistant Students

NCT07735663
View directory record Official record
Conditions
Focus of Study Pain Knowledge
Interventions
Pain education
Other
Lead sponsor
Belmont University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 10, 2026, 11:02 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Neuroscience of Alcohol and Marijuana Impaired Driving

NCT03431987
View directory record Official record
Conditions
Marijuana Usage, Alcohol Drinking
Interventions
One day with a dose of placebo cannabis paired with alcohol, One day with a dose of active THC cannabis paired with alcohol
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
21 Years to 40 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Causal Role of Brain Networks in Episodic Memory

NCT05374551
View directory record Official record
Conditions
Episodic Memory, Healthy
Interventions
Transcranial magnetic stimulation
Other
Lead sponsor
Boston College
Other
Eligibility
18 Years to 35 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional Results available

Complications Associated With Central Venous Access in the NSICU: PICC vs CVC

NCT02314520
View directory record Official record
Conditions
PICC, Central Venous Catheter, Central Line, Neuro ICU, Neuroscience ICU, CVC
Interventions
peripherally inserted central catheter, centrally inserted central catheter
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 10, 2026, 11:02 PM EDT
Completed Not applicable Interventional

The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain

NCT02449876
View directory record Official record
Conditions
Back Pain, Lower Extremity Pain
Interventions
Neuroscience Education
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Sep 10, 2026, 11:02 PM EDT