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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Neurosciences Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Neuroscience of Guided Learning in Depression

NCT03203954
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Standard Learning, Guided Learning: Instructed statistics, Guided Learning: Changing statistics
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 55 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study

NCT02726906
View directory record Official record
Conditions
Aging, Cognitive Ability, General
Interventions
Moderate-aerobic walking, Positron Emission Tomography (PET) scan, Healthy living education, Physical activity monitor
Behavioral · Radiation · Device
Lead sponsor
University of Southern California
Other
Eligibility
55 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Effectiveness of Pain Neuroscience Education (PNE) to Veterans With Post-Traumatic Stress and Low Back Pain

NCT05086159
View directory record Official record
Conditions
Chronic Low Back Pain, Post-traumatic Stress
Interventions
Pain Neuroscience Education, Exercise, Traditional Education
Behavioral
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional

The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain

NCT02449876
View directory record Official record
Conditions
Back Pain, Lower Extremity Pain
Interventions
Neuroscience Education
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Mechanistic Interventions and Neuroscience of Dissociation

NCT04670640
View directory record Official record
Conditions
Dissociation
Interventions
Vibration, Breath Focus, No Distractions
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation

NCT02911805
View directory record Official record
Conditions
Vision Disorders
Interventions
Aerobic exercise, Balance exercise
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Neuroscience of Psychotherapy for Depression

NCT06696001
View directory record Official record
Conditions
Depression
Interventions
Psychoeducation, Behavioral Activation
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motor Training in PD

NCT02457832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Adapted Tango Dancing, Behavioral Control (BC) Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults

NCT05888142
View directory record Official record
Conditions
Pain, Chronic
Interventions
in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Psychological Mechanisms of Pain Perception

NCT02446262
View directory record Official record
Conditions
Pain, Normal Physiology, Healthy Volunteers
Interventions
Instructions, Attention, Thermal Pain, Placebo instructions
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Phase 2 Interventional Results available

Enhancing Self Regulation Among Smokers

NCT04161144
View directory record Official record
Conditions
Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
Interventions
sirolimus, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting No phase listed Observational

Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

NCT00025935
View directory record Official record
Conditions
Mood Disorder
Interventions
Lithium
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 60 Years
Enrollment
2,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

UCLA Fitness and Memory Study of Activity In Mild Cognitive Impairment (AIM)

NCT02001441
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 89 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Phase 4 Interventional Results available

Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention

NCT00618436
View directory record Official record
Conditions
Traumatic Brain Injury, Subarachnoid Hemorrhage
Interventions
Levetiracetam, Phenytoin
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2014 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Neuroscience to Optimize Digital Health Interventions Across Adulthood

NCT03744052
View directory record Official record
Conditions
Healthy
Interventions
Motivational Messages
Other
Lead sponsor
Duke University
Other
Eligibility
30 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 9, 2026, 3:14 AM EDT
Not listed Not applicable Interventional

The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain

NCT05571215
View directory record Official record
Conditions
Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
Interventions
Transcranial Direct Current Stimulation, Pain Neuroscience Education
Device · Behavioral
Lead sponsor
High Point University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

NCT06383091
View directory record Official record
Conditions
Total Thyroidectomy
Interventions
Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches, Scar massage, Voice Exercises, Placebo Anterior Neck Manual Therapy, Placebo Pain Neuroscience Education, Placebo Neck Stretches
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study

NCT06333925
View directory record Official record
Conditions
Misophonia, Emotion Dysregulation, Sensory Processing Disorder, Auditory Over Responsivity, Anxiety Disorder, Sound Sensitivity
Interventions
High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS), Cognitive Restructuring
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

fMRI Neurofeedback With Matter Neuroscience App

NCT06735885
View directory record Official record
Conditions
Depression Mild, Depression, Depression Moderate
Interventions
Matter Neuroscience App, Stock Photos, No Home Training, Personal Photos, Home Training
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Feasibility of Virtual Reality Delivery of Pain Neuroscience Education

NCT05285462
View directory record Official record
Conditions
Low Back Pain
Interventions
VR Pain Education, Usual Care Physical Therapy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses

NCT04822194
View directory record Official record
Conditions
Affect, Bereavement, Emotions, Depressive Symptoms, Grief
Interventions
Cognitive Emotion Regulation Training
Behavioral
Lead sponsor
Bryan Denny
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 9, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wisconsin Center for the Neuroscience and Psychophysiology of Meditation

NCT02157766
View directory record Official record
Conditions
Mindfulness, Compassion, Meditation, Mental Health, Asthma
Interventions
Intensive Meditation Practice, Mindfulness Based Stress Reduction, Health Enhancement Program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Sep 9, 2026, 3:14 AM EDT
Completed No phase listed Observational

PNE Delivered With a VR Headset in Outpatient LBP Patients

NCT04777877
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain Neuroscience Education delivered via a Virtual Reality Headset
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 9, 2026, 3:14 AM EDT
Completed No phase listed Observational

ARC in Hemorrhagic Stroke

NCT02386202
View directory record Official record
Conditions
Hemorrhagic Stroke, Augmented Renal Clearance
Interventions
No intervention
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Sep 9, 2026, 3:14 AM EDT