Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jun 26, 2026, 7:54 AM EDT

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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Postural Orthostatic Tachycardia Syndrome (POTS), POTS, Orthostatic Intolerance
Interventions
Pyridostigmine, Digoxin, Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
15 Years to 30 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Hawthorne, New York
Conditions
Intracranial Aneurysm
Interventions
Penumbra Smart Coil, Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
995 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
71
States / cities
Dothan, Alabama • Mesa, Arizona • Phoenix, Arizona + 62 more
Conditions
Migraine Disorders, Refractory Migraine, Chronic Migraine
Interventions
TEMMA Endovascular Treatment
Device
Lead sponsor
Cortex Neurovascular
Industry
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tacoma, Washington
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study

NCT03617302
Conditions
Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension, Cognitive Decline
Interventions
Experimental: Nitrate-containing, Placebo: Nitrate-depleted
Drug
Lead sponsor
Gary L. Pierce, PhD
Other
Eligibility
50 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Recruiting Not applicable Interventional Accepts healthy volunteers

Kidney Blood Flow During Exercise in Older African American Adults

NCT07029165
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Chronic Kidney Disease
Interventions
Sodium Bicarbonate, Exercise Training, Placebo
Drug · Behavioral
Lead sponsor
Emory University
Other
Eligibility
40 Years to 75 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia • Decatur, Georgia
Conditions
Stroke, Mild Cognitive Impairment
Interventions
Transcranial Dirrect Current Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Prostate Cancer Adenocarcinoma
Interventions
30Gy (Gray) planning target volume (PTV)
Radiation
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2029
U.S. locations
8
States / cities
San Francisco, California • Aurora, Colorado • Colorado Springs, Colorado + 5 more
Completed Not applicable Interventional Accepts healthy volunteers

Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System

NCT02193373
Conditions
Osteopathic Manual Manipulation of Neurovascular Regulation
Interventions
Osteopathic Manual Medicine, Sham
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
20 Years to 50 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Old Westbury, New York
Completed Not applicable Interventional Results available

SOLITAIRE™ FR With the Intention For Thrombectomy (SWIFT) Study

NCT01054560
Conditions
Ischemic Stroke
Interventions
SOLITAIRE™ Device, MERCI® Device
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Portland, Oregon • Tacoma, Washington
Conditions
Intracranial Aneurysms
Interventions
Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Albany, New York • Stony Brook, New York • Philadelphia, Pennsylvania + 3 more
Conditions
Intracranial Aneurysm
Interventions
Pipeline Embolization Device (PED), Coil embolization
Device
Lead sponsor
Chestnut Medical Technologies
Industry
Eligibility
21 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
Phoenix, Arizona • Stony Brook, New York
Completed Not applicable Interventional Results available

Pipeline for Uncoilable or Failed Aneurysms

NCT00777088
Conditions
Intracranial Aneurysm
Interventions
Pipeline Embolization Device (PED)
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
21 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
8
States / cities
Phoenix, Arizona • Chicago, Illinois • Winfield, Illinois + 5 more
Completed Not applicable Interventional Accepts healthy volunteers

Measuring the Neurological Benefits of Intermittent Hypoxia Therapy With MRI

NCT05183113
Conditions
Spinal Cord Injuries
Interventions
Acute Intermittent Hypoxia
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Stroke
Interventions
Penumbra System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Aneurysm, Intracranial
Interventions
Contour Neurovascular System
Device
Lead sponsor
Cerus Endovascular, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
20
States / cities
Englewood, Colorado • Jacksonville, Florida • Chicago, Illinois + 16 more
Conditions
Prostate Cancer
Interventions
Stravix lyopreserved placental tissue (LPT), Radical prostatectomy
Drug · Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Wound Closure, Brain Tumor Adult, Spine, Neurovascular, Hemorrhagic Stroke, Intracerebral, Traumatic Brain Injury
Interventions
STRATAFIX PDS and Monocryl suture
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lansing, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Meal Timing and Blood Pressure

NCT04133701
Conditions
Blood Pressure, Neurovascular Control
Interventions
Time-Restricted Feeding
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Spontaneous Coronary Artery Dissection, Healthy
Interventions
Arterial Tonometry, Echocardiogram, Carotid Ultrasounds, Elastography, Ankle-Brachial Index, Microneurography with sympathoexcitatory maneuvers
Other · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Withdrawn No phase listed Observational Accepts healthy volunteers

Neurovascular Complications and White Matter Damage in Acquired Anemias

NCT04320966
Conditions
Anemia, Iron-deficiency Anemia, Healthy Controls
Interventions
Not listed
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
16 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
4
States / cities
Duarte, California • Los Angeles, California
Not listed No phase listed Observational Accepts healthy volunteers

Clinical Proteomic Research for the Brain

NCT00983723
Conditions
Ischemic Brain Injury, Stroke, Healthy Individual, Patent Foramen Ovale (PFO), Neurovascular Injury
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Acute Ischemic Stroke
Interventions
RapidPulseTM Aspiration System
Device
Lead sponsor
RapidPulse, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
18
States / cities
Torrance, California • New Haven, Connecticut • Jacksonville, Florida + 15 more
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Cardiovascular and Neurovascular Regulation in GWI

NCT04586049
Conditions
Brain Blood Flow, Neurovascular Control
Interventions
MRI, Transcranial Doppler Ultrasound, Sympathetic Nerve Activity
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 68 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin