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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:06 PM EST

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Showing 25–48 of 130 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Nicotine Replacement Therapy Clear all

Conditions: Tobacco Use Disorder
Interventions: Bupropion; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 75 Years
Enrollment: 589 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2006
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking Cessation
Interventions: CQSS2, NicoDerm CQ Patch; Drug
Lead sponsor: Chrono Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 5
States / cities: Mobile, Alabama • Tempe, Arizona • Lexington, Kentucky + 2 more

Conditions: Smoking, Alcoholism
Interventions: Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Newington, Connecticut

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Bupropion Hydrochloride Controlled-release, Nicotine Replacement, Questionnaire Administration, Tobacco Cessation Counseling, Varenicline; Drug · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 2,010 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Nicotine Addiction, Smoking Cessation
Interventions: Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer; Drug · Other
Lead sponsor: Creighton University; Other
Eligibility: 19 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Cervical Dysplasia
Interventions: Nicotine Replacement Therapy, Electronic Cigarettes; Other · Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Cigarette Smoking
Interventions: Ask-Advise-Refer, Nicotine Patch, 14 Mg/24 Hr Transdermal Film, Extended Release, Nicotine lozenge; Behavioral · Drug
Lead sponsor: Sandra Japuntich; Other
Eligibility: 18 Years and older
Enrollment: 1,239 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: Brief Intervention with NRT Initiation; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Use Disorder
Interventions: nicotine transdermal system; Drug
Lead sponsor: New York University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 585 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 13
States / cities: Los Angeles, California • Tarzana, California • Miami, Florida + 8 more

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Behavioral Intervention, Laboratory Biomarker Analysis, Nicotine Patch, Questionnaire Administration, Smoking Cessation Intervention; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Nicotine transdermal patch; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 23 Years to 60 Years · Male only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking Cessation
Interventions: Nicotine (2 mg), Nicotine (4 mg); Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 19 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Endothelial Dysfunction
Interventions: Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Placebo, Smoking cessation; Other · Dietary Supplement · Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 60 Years
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Secondhand Smoke
Interventions: Quitline Delivered Treatment; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 18 Years and older
Enrollment: 484 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking Cessation
Interventions: WEB, Social Network, Nicotine Replacement Therapy (NRT); Behavioral
Lead sponsor: Truth Initiative; Other
Eligibility: 18 Years and older
Enrollment: 5,292 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Tobacco Use Disorder
Interventions: ModafinilNicotine Replacement Therapy, Modafinil; Drug
Lead sponsor: Catherine Martin, MD; Other
Eligibility: 16 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Nicotine Dependence
Interventions: nicotine patch (Nicoderm Committed Quitter (CQ), Habitrol), denicotinized cigarettes (Quest 3 cigarettes); Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 60 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cigarette Smoking
Interventions: D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo; Drug · Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking Cessation
Interventions: Varenicline, Oral Nicotine Replacement Therapy (NRT), Medication Reminders, Tobacco Cessation Counseling; Drug · Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Tobacco Use Disorder
Interventions: placebo, 2 mg nicotine polacrilex; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 16 Years to 50 Years · Female only
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2007
U.S. locations: 4
States / cities: Farmington, Connecticut • Hartford, Connecticut • New Britain, Connecticut + 1 more

Conditions: Drug Addiction, Smoking Cessation
Interventions: Nicotine transdermal system, Nicotine containing cigarette, Placebo cigarette; Drug · Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking
Interventions: CBME, Optional NRT; Behavioral · Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 14 Years to 21 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking, Cigarette, Smoking Cessation
Interventions: Smoking Cessation iPad Decision Aid Tool; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 100 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Smoking Cessation
Interventions: Nicotine Patch, Telephone Counseling, Placebo, Self-Help Materials; Drug · Behavioral · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 4,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: San Diego, California

Search by objective public record fields.

Maintenance Treatment for Abstinent Smokers

Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects

Combination Nicotine Replacement for Alcoholic Smokers

Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

e-Cigarettes Versus NRT Gum for Smoking Cessation

Smoking Cessation in Women With Gynecological Conditions

Free Samples for Health

Treating Low-Income Smokers in the Hospital Emergency Department

Smoking Cessation Treatment With Transdermal Nicotine Replacement Therapy - 1

Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation

Smoking Cessation and Sexual Health in Men

Nicotine Lozenge Bioequivalence Study

Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function

Parent eReferral to Tobacco Quitline

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents

Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes

Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers

Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy (COMBO)

Nicotine Replacement Treatment for Pregnant Smokers - 1

Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3

Youth Smoking Cessation: Therapy +/- "The Patch"

Feasibility of a Decision Aid for E-Cigarettes in Primary Care

Telephone Counseling and the Distribution of Nicotine Patches to Smokers