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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 130 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Nicotine Replacement Therapy Clear all

Conditions: Smoking Cessation
Interventions: Nicorette Gum, Nicoderm CQ, Smoking Quitline Referral, Behavioral Smoking Cessation Counseling; Drug · Other · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older · Male only
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Tobacco Use Disorder, Smoking
Interventions: Ariva Silver Wintergreen, Placebo Wintergreen; Other
Lead sponsor: Star Scientific, Inc; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Cigarette Smoking, Tobacco Use, Cigarette Smoking Behavior
Interventions: HRP Sampling period, NPL Sampling period; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 21 Years and older
Enrollment: 472 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nicotine Dependence, Schizophrenia
Interventions: NRT, Bupropion SR 150mg bid, Relapse Prevention-Oriented Cognitive Behavioral Therapy; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Disorder
Interventions: Lower Nicotine Smokeless Tobacco Product, Behavioral Counseling; Other
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 70 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking, Pregnancy
Interventions: Nicotine Replacement Therapy; Behavioral
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 21 Years and older · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 2
States / cities: Washington D.C., District of Columbia

Conditions: Tobacco Use Disorder, Smoking
Interventions: Ariva® Silver Wintergreen, Silver Wintergreen; Other
Lead sponsor: Star Scientific, Inc; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Cardiovascular Disease, Tobacco Use Disorder
Interventions: Nicotine replacement, Motivational counseling; Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 2
States / cities: Minneapolis, Minnesota

Conditions: Growth Hormone Deficiency, Pediatric, Endocrine System Diseases, Hormone Deficiency, Pituitary Diseases
Interventions: TransCon hGH; Drug
Lead sponsor: Ascendis Pharma A/S; Industry
Eligibility: 1 Year to 18 Years
Enrollment: 298 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 22
States / cities: Birmingham, Alabama • Los Angeles, California • Orange, California + 18 more

Conditions: Cigarette Smoking
Interventions: Smoking research cigarettes with or without NRT; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Smoking Cessation, Harm Reduction
Interventions: Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product, BIDI e-cigarette, on!; Drug · Other
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Smoking, Smoking Cessation
Interventions: Nicotine Replacement Therapy (NRT) Sampling, Ask, Advise, Refer (physician brief advice); Other · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 1,278 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Drinking
Interventions: 21mg transdermal nicotine patch (Nicoderm CQ), 1mg nicotine nasal spray, placebo nasal spray; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation
Interventions: Brief Advice, Motivational Interviewing, Rate Reduction, Pharmacological, MI+RR; Behavioral · Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 903 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Tobacco Use
Interventions: Nicotine Replacement Therapy, Counseling; Drug · Behavioral
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years to 64 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking Cessation
Interventions: Project Quit stop smoking program, Nicotine patches 21 mg; Behavioral · Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 767 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cigarette Smoking, Smoking Cessation, Depression
Interventions: Treatment as Usual, Goal2Quit + NRT Sampling; Behavioral · Combination Product
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Smoking Cessation, Electronic Cigarette Use, Cigarette Smoking
Interventions: Regular Nicotine patch and lozenge dose, Augmented Nicotine patch and lozenge dose; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tobacco Smoking
Interventions: Nicoderm C-Q Transdermal Product, Orientation session, Craving-to-Quit app, Two brief follow-up phone calls, Group MT sessions, Brief advice on quitting smoking, Self-help smoking cessation materials; Drug · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Miami, Florida • Memphis, Tennessee

Conditions: Tobacco Use Disorder
Interventions: Nicotrol; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 79 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1993 – 2000
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: bupropion, transdermal nicotine patch; Drug
Lead sponsor: North Suffolk Mental Health Association; Other
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Cessation
Interventions: Varenicline plus Motivational Interviewing counseling, Varenicline without counseling; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 428 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking Cessation
Interventions: Stepped-Care, Control; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Walnut Creek, California

Conditions: Smoking, Cardiovascular Disease Risk
Interventions: Resistance Training (RT), Nicotine Replacement Therapy (NRT); Other · Biological
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 35 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Smoking Cessation in Hispanic Construction Workers

A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia

Using Smokeless Tobacco Products With Lower Nicotine Levels to Reduce Negative Effects of Smokeless Tobacco Use

Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers

Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers

Reduction of Smoking in Cardiac Disease Patients

A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial

Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes

Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT

Tobacco Intervention in Primary Care Treatment Opportunities for Providers

Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy

Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit

Jail-Based Use of Smoking Cessation Treatment Study

Project Quit: Positive vs. Negative Offers of an Online Stop Smoking Program

Goal2Quit + NRT Sampling

CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes

Mindfulness Based Smoking Cessation Among Cancer Survivors

Tobacco Cessation in Postmenopausal Women (Part II) - 2

Nicotine Replacement Therapy for Smoking Cessation in Schizophrenia

Improving Varenicline Adherence and Outcomes in Homeless Smokers

Interventions for Smoking Among Persons in Recovery

Effect of Resistance Training on Tobacco-Related Cardiovascular Disease Risk