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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Nitrates Clear all
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Granulation Tissue Treatment: Silver Nitrate vs Kenalog vs Washcloth Abrasion

NCT02519738
View directory record Official record
Conditions
Other Abnormal Granulation Tissue Nos
Interventions
Silver Nitrate, Kenalog (Triamcinolone), Washcloth Abrasion
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
Up to 17 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Early Phase 1 Interventional

Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome

NCT05532423
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Strength Testing After Nitrate Delivery (STAND) in ICU Patients

NCT02293616
View directory record Official record
Conditions
Respiratory Failure
Interventions
Nitrate Rich Beetroot Juice, Placebo
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
56 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Juice Types on the Responses to Air Pollution

NCT02027415
View directory record Official record
Conditions
Air Pollution
Interventions
Beet juice, Orange juice
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Jul 21, 2026, 7:45 PM EDT
Not listed Phase 2 Interventional

Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD

NCT02553733
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Beetroot juice, Beetroot juice placebo
Drug
Lead sponsor
David N. Proctor, PhD
Other
Eligibility
21 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Flushing Reduction Associated With Nitrates

NCT02714205
View directory record Official record
Conditions
Menopausal Hot Flashes
Interventions
transdermal nitroglycerin, Placebo
Drug
Lead sponsor
Alison Huang, MD
Other
Eligibility
40 Years to 62 Years · Female only
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Not yet recruiting Not applicable Interventional

Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA

NCT06948201
View directory record Official record
Conditions
Coronary Microvascular Dysfunction (CMD), Angina Patients With Non-obstructive Coronary Artery Disease
Interventions
70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice), Placebo (70 mL Nitrate depleted beetroot juice) followed by 70mL Nitrate Rich Beetroot Juice
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Phase 1 Interventional

IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

NCT04294043
View directory record Official record
Conditions
Nontuberculous Mycobacterium Infection
Interventions
Gallium nitrate
Drug
Lead sponsor
Chris Goss
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
10
States / cities
Birmingham, Alabama • Denver, Colorado • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina

NCT00194324
View directory record Official record
Conditions
Health, Vulvovaginal Candidiasis
Interventions
Miconazole nitrate, Magnetic resonance imaging, Moderate levels of exercise
Drug · Procedure · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2011 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Pharmacokinetics of Berkeley Life Oral Nitrate Supplementation

NCT06777108
View directory record Official record
Conditions
Hypertension
Interventions
Inorganic Nitrate
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

NCT03545009
View directory record Official record
Conditions
Metabolic Disease, Obesity, Exercise
Interventions
Sodium Nitrate, Beetroot Juice no Nitrate, Beetroot Juice
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Jul 21, 2026, 7:45 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Silver Nitrate vs. Triamcinolone for Treatment of Hypergranulation Tissue

NCT06681194
View directory record Official record
Conditions
Wound Healing, Granulation Tissue
Interventions
Silver Nitrate, triamcinolone, Silver nitrate + triamcinolone
Drug
Lead sponsor
Francesco Egro
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional

Cardiovascular Function in Cancer Survivors

NCT03776149
View directory record Official record
Conditions
Cancer Survivor With History of Anthracycline Chemotherapy
Interventions
Beetroot juice, Black currant juice
Dietary Supplement
Lead sponsor
Kansas State University
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Jul 21, 2026, 7:45 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances

NCT02949115
View directory record Official record
Conditions
Overweight, Obesity, Aging, Menopause
Interventions
70 mL red beetroot juice, 70 mL red beetroot juice without nitrate, 70 mL placebo drink plus potassium nitrate, 70 mL placebo drink
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
40 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 2 Interventional Results available

Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF

NCT02256345
View directory record Official record
Conditions
Heart Failure, Diastolic Heart Failure
Interventions
KNO3, KCl
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Dietary Nitrate Supplementation and Thermoregulation

NCT03506646
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Artery Disease
Interventions
Placebo, Beet root juice
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices

NCT03267511
View directory record Official record
Conditions
Oral Hygiene
Interventions
5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica, 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP, 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica, 5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response

NCT02797184
View directory record Official record
Conditions
Heart Failure
Interventions
KNO3, potassium nitrate
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% Formulations

NCT01039584
View directory record Official record
Conditions
Vulvovaginal Candidiasis
Interventions
Butoconazole Nitrate Vaginal Cream, Placebo, Gynazole 1 vaginal cream
Drug
Lead sponsor
Padagis LLC
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
611 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of the Combination of Nitrate and Caffeine on Critical Power In Trained Male Cyclists

NCT07501806
View directory record Official record
Conditions
Exercise Performance of Fit Athletes, Exercise Performance, Cycling Performance
Interventions
Dietary Nitrate, Caffeine, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 2 Interventional Results available

Nitrate Effect on Exercise Capacitance

NCT04297241
View directory record Official record
Conditions
Fontan
Interventions
Isosorbide Dinitrate
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
9 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women

NCT04125940
View directory record Official record
Conditions
Healthy
Interventions
Resync, Resync + Collagen, Placebo
Dietary Supplement · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )

NCT06375694
View directory record Official record
Conditions
Hypertension, Cardiovascular Diseases, Diabetes
Interventions
Herbiotics Oral + Ent Probiotic, Placebo
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Jul 21, 2026, 7:45 PM EDT