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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nocturnal Awakening Clear all
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Good Nights Sleep Program to Improve Child and Family Sleep

NCT06249217
View directory record Official record
Conditions
Sleep Problems, Sleep Hygiene
Interventions
Good Nights Sleep Program
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
7 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Jul 22, 2026, 5:48 PM EDT
Not yet recruiting Not applicable Interventional

The Role of Timed Awakening in Treatment of Enuresis

NCT06586476
View directory record Official record
Conditions
Nocturnal Enuresis, Voiding Dysfunction
Interventions
Nightly Timed Awakening
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
6 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Duration and Blood Pressure During Sleep

NCT05062161
View directory record Official record
Conditions
Blood Pressure, Hypertension, Elevated Blood Pressure, Sleep, Short Sleep Phenotype
Interventions
Sleep hygiene/extension intervention, Control care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 22, 2026, 5:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SNORE (Smartphone Analyses of Nocturnal Obstruction by Respiratory Evaluation) SOUNDS

NCT03288376
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Chronic Obstructive Pulmonary Disease
Interventions
Not listed
Lead sponsor
Incyphae, Inc.
Industry
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Burlingame, California • New London, Connecticut • Lanham, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Night Respite for Postpartum Mothers With SUD

NCT05746507
View directory record Official record
Conditions
Opioid Use Disorder, Maternal Drugs Affecting Fetus, Postpartum Mood Disturbance, Sleep Disorder, Neonatal Opioid Withdrawal
Interventions
Night Respite Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Mattapan, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea

NCT00859950
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypoxemia
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Jul 22, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Operational Naps on Blood Pressure and Performance Among Night Shift Workers

NCT07217769
View directory record Official record
Conditions
Shift Work
Interventions
No-nap, 15-min nap, 30-min nap, 45-min nap, 60-min nap
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 22, 2026, 5:48 PM EDT
Not listed No phase listed Observational

Is My Sleep Tracker Tracking my Sleep?

NCT06174558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Sleep Tracking Devices
Device
Lead sponsor
Respiratory Specialists
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Wyomissing, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blue Blockers at Night and Insomnia Symptoms

NCT02698800
View directory record Official record
Conditions
Insomnia, Sleep
Interventions
Blue blocking (BB) lenses, Clear lenses
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Jul 22, 2026, 5:48 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)

NCT01261377
View directory record Official record
Conditions
Chronic Obstructive Airway Disease
Interventions
Bi-level positive airway pressure (BPAP), Oxygen, CPAP
Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Jul 22, 2026, 5:48 PM EDT
Terminated Not applicable Interventional Results available

Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for Anxiety

NCT00746239
View directory record Official record
Conditions
Panic Disorder, Insomnia
Interventions
Placebo and Escitalopram, Ramelteon and Escitalopram
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Jul 22, 2026, 5:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Vitamin D for Painful Nocturnal Leg Cramps

NCT00715429
View directory record Official record
Conditions
Leg Cramps, Nocturnal
Interventions
vitamin d, placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Jul 22, 2026, 5:48 PM EDT
Terminated Not applicable Interventional

Effects of Nocturnal Nasal Oxygen on Biomarkers in Sleep Apnea Patients With Heart Failure

NCT01431157
View directory record Official record
Conditions
Sleep Apnea, Heart Failure
Interventions
Nocturnal nasal oxygen, No nasal oxygen
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Jul 22, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers

NCT06809335
View directory record Official record
Conditions
Shift Work Sleep Disorder
Interventions
Personalized circadian mHealth
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skeletal Response to Simulated Night Shift

NCT05074277
View directory record Official record
Conditions
Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Interventions
Simulated short term night shift work schedule
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction

NCT04868539
View directory record Official record
Conditions
Glucose Intolerance, Sleep Deprivation, Sleep
Interventions
Sleep Restriction with ALAN first, then Sleep Restriction without ALAN, Sleep Restriction without ALAN first, then sleep restriction with ALAN
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Infant Behavioral Sleep Intervention: Comparative Efficacy

NCT03447665
View directory record Official record
Conditions
Insomnia
Interventions
Bedtime routine, Sleep schedule, Intervention (bedtime), Intervention (after night wakings)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
6 Months to 18 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Eplivanserin 5mg/Day on Sleep Maintenance Insomnia

NCT00308503
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Insomnia
Interventions
eplivanserin (SR46349), placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bridgewater, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2010 · Synced Jul 22, 2026, 5:48 PM EDT
Terminated Phase 3 Interventional Results available

The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea

NCT03745898
View directory record Official record
Conditions
Heart Failure, Central Sleep Apnea
Interventions
Oxygen, Room Air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
26
States / cities
Tucson, Arizona • Stanford, California • New Haven, Connecticut + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional

This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.

NCT06666426
View directory record Official record
Conditions
Adult Nocturnal Enuresis, Urinary Incontinence (UI)
Interventions
PureWick System, Hollister Female Urinary Pouch External Collection Device
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
15
States / cities
Guntersville, Alabama • Chandler, Arizona • Eagle Rock, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 22, 2026, 5:48 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Brain Sleep Deprivation MRI Effects (BEDTIME)

NCT02741505
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Actigraph
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use Of The Dietary Supplement 5-ALA And Its Relationship With Sleep And Mood

NCT01508741
View directory record Official record
Conditions
Insomnia, Nocturnal Awakening, Irritability, Coping Behavior, Stress
Interventions
5-Aminolevulinic Acid (5-ALA), Placebo
Dietary Supplement
Lead sponsor
University of Hawaii
Other
Eligibility
40 Years to 70 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Safety of the Nocturnal Passy Muir Valve and Impact on Sleep Quality at an LTACH Setting

NCT06229639
View directory record Official record
Conditions
Tracheostomy
Interventions
Passy Muir Valve, Tracheostomy Plug
Device
Lead sponsor
Gaylord Hospital, Inc
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Wallingford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 22, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms

NCT03159260
View directory record Official record
Conditions
Leg Cramp, Nocturnal
Interventions
Theraworx, Placebo
Device · Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Jul 22, 2026, 5:48 PM EDT