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ClinicalTrials.gov public records Last synced Nov 4, 2026, 3:18 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 108 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Non-invasive Ventilation Clear all

Conditions: Respiratory Insufficiency, Respiratory Failure
Interventions: Not listed
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Denver, Colorado • Columbus, Ohio

Conditions: BPD - Bronchopulmonary Dysplasia
Interventions: NAVA technology to synchronize NIPPV; Device
Lead sponsor: New York Medical College; Other
Eligibility: 24 Weeks to 30 Weeks
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Valhalla, New York

Conditions: Elective Procedures Requiring Mechanical Ventilation
Interventions: VQm PHM™; Device
Lead sponsor: Rostrum Medical Innovations Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
Interventions: Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor); Device
Lead sponsor: Lawrence Rhein; Other
Eligibility: 5 Days and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Copd
Interventions: Interprofessional Education (IPE), Usual care; Other
Lead sponsor: Baystate Medical Center; Other
Eligibility: 23 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Tracheobronchomalacia
Interventions: nPEP (non-invasive positive expiratory pressure) mask; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Apnea of Prematurity, Hypoxia, Bradycardia
Interventions: Vibration; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 1 Week and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Los Angeles, California • Santa Monica, California

Conditions: Copd, Chronic Obstructive Pulmonary Disease, Hypercapnia, Chronic Respiratory Failure, Hypoventilation
Interventions: High-intensity non-invasive ventilation; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 45 Years to 75 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions: noninvasive positive pressure ventilation; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Premature Infant Disease, Respiratory Insufficiency
Interventions: non-synchronized NIMV, Synchronized NIMV; Other
Lead sponsor: University of Miami; Other
Eligibility: Not listed
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Acute Respiratory Failure, Airway Extubation
Interventions: Traditional online education, Interprofessional education, Clinical protocol, Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC), Preventive post-extubation high-flow nasal cannula oxygen (HFNC); Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 12,857 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 17
States / cities: Carlisle, Pennsylvania • Hanover, Pennsylvania • Harrisburg, Pennsylvania + 7 more

Conditions: Respiratory Distress Syndrome, Newborn, Apnea of Newborn
Interventions: NIV plus software; Device
Lead sponsor: Keck School of Medicine of USC; Other
Eligibility: 0 Days to 30 Days
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Status Asthmaticus
Interventions: Noninvasive positive pressure ventilation; Other
Lead sponsor: Southern Illinois University; Other
Eligibility: 1 Year to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Respiratory Insufficiency, Respiration, Artificial, Sleep Deprivation
Interventions: Not listed
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BiPAP Synchrony ventilator; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Severe Obesity, Hypoxia
Interventions: Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers; Device · Other
Lead sponsor: Bristol Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Bristol, Connecticut

Conditions: Heart Failure, Hypertension
Interventions: Not listed
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Imperial, California

Conditions: Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxia
Interventions: Humidified nasal high flow with oxygen; Device
Lead sponsor: Temple University; Other
Eligibility: 40 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
Interventions: Bipap procedure; Procedure
Lead sponsor: United States Air Force; Federal
Eligibility: 35 Years to 80 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Wpafb, Ohio

Conditions: Dyspnea, Acute Decompensated Heart Failure
Interventions: Recording Doppler ultrasound signals noninvasively; Device
Lead sponsor: Echosense Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Single-ventricle
Interventions: Hands-free oral-positive pressure device (oPEP); Device
Lead sponsor: Tarek Alsaied; Other
Eligibility: 8 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: COVID-19, COVID, Coronavirus
Interventions: Continuous Positive Airway Pressure; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Morbid Obesity, Noninvasive Ventilation, Deep Sedation
Interventions: High flow nasal cannula, Nasal Cannula; Device
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Respiratory Distress Syndrome (RDS)
Interventions: LISA combination product (Curosurf+catheter CHF6440), Curosurf through conventional administration (endotracheal tube); Combination Product · Drug
Lead sponsor: Chiesi Farmaceutici S.p.A.; Industry
Eligibility: 30 Minutes to 24 Hours
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 26
States / cities: Little Rock, Arkansas • Los Angeles, California • Denver, Colorado + 22 more

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Novel Non-Invasive Monitoring Parameter in a Hospital Setting

Randomized Control Trial: Synchronized Non-invasive Positive Pressure Ventilation Versus Non Synchronized Non Invasive Positive Pressure Ventilation in Extremely Low Birth Weight Infants

Evaluation of Novel Cardio-Pulmonary Physiological Monitor, the VQm PHM™, for Acute Care Medicine

Relationship Between EIT and Respiratory Status in Very Preterm Infants

The Impact of Interprofessional Training to Improve the Uptake of Noninvasive Ventilation in Patients Hospitalized With Severe COPD Exacerbation

PEEP Mask for Tracheobronchomalacia-Induced Cough

Non-invasive Intervention for Apnea of Prematurity

Impact of Non-invasive Ventilation in Hypercapnic COPD

Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis

Flow-synchronized Nasal IMV in Preterm Infants

The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus Software

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

Effects Of Invasive And Noninvasive Mechanical Ventilation On Sleep In The Intensive Care Unit (ICU)

The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants

Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures

Necklace-Shaped Sensor for Non-Invasive Remote Monitoring of Vitals

Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients

Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome

Evaluation of Cardiopulmonary Diseases by Ultrasound

Simple Non-invasive Breathing Device to Improve Pulmonary Flow Pusatility in Single Ventricle Post Fontan

Early CPAP in COVID-19 Confirmed or Suspected Patients

Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite

A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration