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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Conditions
Apical Periodontitis
Interventions
GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
DENT IMPLANTS, LASER
Interventions
Conventional mechanical therapy, Saline, Methylene Blue, Light emitting laser, Non-light emitting laser
Procedure · Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
SRP, Minocycline HCl Microspheres, Biomarkers
Interventions
Measurement of Biomarkers
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Utilization of a Periodontal Endoscope in Nonsurgical Periodontal Therapy

NCT05293301
Conditions
Periodontitis, Adult
Interventions
Use of Periodontal Endoscope (Perioscopy®) to enhance visualization while performing teeth deep cleaning, Use of traditional loupes to enhance magnification to enhance visualization while performing teeth deep cleaning
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Periodontitis, Probiotic, Oral Hygiene, Oral Health, Periodontal Therapy
Interventions
non surgical periodontal therapy
Procedure
Lead sponsor
Medipol University
Other
Eligibility
18 Years to 70 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Periodontal Diseases
Interventions
mechanical debridement, adjunctive aPDT, sham aPDT
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 4 Interventional Accepts healthy volunteers

PRF + Minocycline vs Arestin in Non-surgical Perio Therapy

NCT07437209
Conditions
Non-surgical Periodontal Therapy
Interventions
Arestin, PRF + M
Drug · Biological
Lead sponsor
Center for Advanced Rejuvenation and Esthetics
Network
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sarasota, Florida
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Addition of Dehydrated Human Amnion-Chorion Membrane During Scaling and Root Planing

NCT03836378
Conditions
Periodontal Diseases
Interventions
BioXclude™
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg

NCT03762915
Conditions
SRP, Minocycline HCl Microspheres, Biomarkers
Interventions
minocycline HCl microspheres
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Chronic Periodontitis, Type 2 Diabetes
Interventions
Non-surgical periodontal therapy, Delayed non-surgical periodontal therapy
Procedure · Other
Lead sponsor
Stony Brook University
Other
Eligibility
35 Years and older
Enrollment
514 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
8
States / cities
Birmingham, Alabama • Minneapolis, Minnesota • Stony Brook, New York + 2 more
Conditions
Chronic Periodontitis
Interventions
Scaling and root planing, Scaling and root planing with solution
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
30 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Periodontal Diseases, Dental Diseases
Interventions
Scaling and root planing
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Type 2 Diabetes Mellitus, Periodontal Disease
Interventions
Periodontal Scaling and root planing
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Conditions
Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
Interventions
Scaling and Root Planing, Diode Laser + Scaling and Root Planing
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
30 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Lincoln, Nebraska