- Conditions
- Mitigation of Fracture Non-union in Patients at Risk
- Interventions
- Low intensity pulsed ultrasound
- Device
- Lead sponsor
- Bioventus LLC
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 12,387 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Jericho, New York
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Showing 1–24
of 27
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Nonunion of Fracture
- Interventions
- Next-generation sequencing of swabs collected during surgery
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Rib Fracture
- Interventions
- Resection with or without plate fixation
- Device
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Non-Union Fracture, Trochanteric Fractures, Femoral Neck Fractures, Avascular Necrosis, Dislocation, Hip
- Interventions
- Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2038
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Los Angeles, California • Gainesville, Florida + 7 more
- Conditions
- Non-union or Delayed Healing Fractures
- Interventions
- Not listed
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 60 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Fractures, Bone, Fractures, Closed, Fractures, Open, Fracture of Femur, Fracture Nonunion, Fracture of Tibia, Limb Deformity, Limb Fracture, Limb Defect, Limb Asymmetry
- Interventions
- Fitbone Transport and Lengthening System
- Device
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Orange, California • Atlanta, Georgia + 6 more
- Conditions
- Clavicle Fracture, Non Union/Malunion
- Interventions
- superior plate, anterior-inferior plate
- Procedure
- Lead sponsor
- United States Army Institute of Surgical Research
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2018
- U.S. locations
- 2
- States / cities
- El Paso, Texas • Fort Sam Houston, Texas
- Conditions
- Tibia Fracture
- Interventions
- Ibuprofen
- Drug
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Neck Injuries, Spinal Injuries
- Interventions
- surgical, conservative treatment
- Procedure
- Lead sponsor
- AOSpine North America Research Network
- Network
- Eligibility
- 64 Years and older
- Enrollment
- 159 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2010
- U.S. locations
- 14
- States / cities
- Atlanta, Georgia • Indianapolis, Indiana • Kansas City, Kansas + 11 more
- Conditions
- Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited, Fracture, Tibial, Fracture of Femur, Fracture Arm
- Interventions
- Vivigen Cellular Bone Matrix
- Other
- Lead sponsor
- LifeNet Health
- Industry
- Eligibility
- Not listed
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 4
- States / cities
- Orlando, Florida • Jersey City, New Jersey • Durham, North Carolina + 1 more
- Conditions
- Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia, Nonunion of Fracture of Femur (Diagnosis), Tibia Fracture
- Interventions
- Distal targeting jig, Free-hand/perfect circles technique
- Device · Procedure
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 89 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Humerus Fractures
- Interventions
- Not listed
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Hypovitaminosis D
- Interventions
- Vitamin D, Placebo
- Dietary Supplement
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 113 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Tibial Fractures, Nonunion of Fracture, Delayed Union of Fracture
- Interventions
- Intramedullary Bone Graft
- Procedure
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Proximal Humeral Fracture, Fracture Dislocation, Non-Union Fracture
- Interventions
- Not listed
- Lead sponsor
- Exactech
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2034
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Orthopaedic Trauma Infections
- Interventions
- Highly Sensitive Assays
- Diagnostic Test
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Nonunion of Fracture of Fifth Metatarsal
- Interventions
- EBI Bone Healing System, Placebo Device, Surgery
- Device · Procedure
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 2
- States / cities
- Newark, New Jersey • Columbus, Ohio
- Conditions
- Nonunion Fracture
- Interventions
- Autograft, Allograft
- Procedure
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
- Interventions
- Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
- Drug
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 13
- States / cities
- Indianapolis, Indiana • Baltimore, Maryland • Minneapolis, Minnesota + 9 more
- Conditions
- Tibial Delayed Healing
- Interventions
- INFUSE/MASTERGRAFT, Autograft bone
- Device · Procedure
- Lead sponsor
- Medtronic Spinal and Biologics
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 16
- States / cities
- Denver, Colorado • Fort Lauderdale, Florida • Jacksonville, Florida + 13 more
- Conditions
- Fractures, Bone
- Interventions
- Blood draws to assess RNA expression levels
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 7
- States / cities
- Sacramento, California • Bloomington, Indiana • Columbia, Missouri + 4 more
- Conditions
- Fracture, Ununited, Pseudarthrosis
- Interventions
- Fracture surgery, Cultured Bone Marrow Tissue
- Procedure · Drug
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 4
- States / cities
- Des Plaines, Illinois • Ann Arbor, Michigan • Royal Oak, Michigan + 1 more
- Conditions
- Rib Fracture, Flail Chest
- Interventions
- U-plate fracture repair system
- Device
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Fracture, Fracture Nonunion, Fractures, Bone, Vitamin D
- Interventions
- Vitamin D Assessment, Fracture
- Other
- Lead sponsor
- Methodist Health System
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Dallas, Texas