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Showing 1–24 of 93 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Normal Aging Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin

NCT03289832
View directory record Official record
Conditions
Healthy Adults
Interventions
Crucera-SGS, Meriva 500-SF
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational

Biomarkers in Blood Samples From Older Breast Cancer Survivors

NCT01138345
View directory record Official record
Conditions
Breast Cancer
Interventions
gene expression analysis, reverse transcriptase-polymerase chain reaction, laboratory biomarker analysis, medical chart review, questionnaire administration
Genetic · Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
50 Years and older · Female only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Following Lipectomy to Understand Adipose Tissue Re-accumulation

NCT00995631
View directory record Official record
Conditions
Menopause, Pre-menopause
Interventions
Femoral lipectomy
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
35 Years to 60 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging

NCT05423873
View directory record Official record
Conditions
Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
Interventions
Gentle Cleansing Lotion, Revision Skincare
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
3
States / cities
Solana Beach, California • Greenwood Village, Colorado • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Memory Imaging of Normal Aging

NCT00315575
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
BOLD and Perfusion brain MRI
Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
25 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2009 · Synced Sep 6, 2026, 1:23 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Behavioral and Physiological Effects of Visual Training

NCT00526942
View directory record Official record
Conditions
Healthy
Interventions
SAAGE-designed, visual memory-based cognitive training
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Francisco Bay Area, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2007 · Synced Sep 6, 2026, 1:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brown Adipose Tissue Pilot

NCT03793127
View directory record Official record
Conditions
Aging
Interventions
Maximal oxygen consumption (V02 max), Brown adipose tissue (BAT) imaging, Muscle function testing
Other
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
20 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 6, 2026, 1:23 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging

NCT01771679
View directory record Official record
Conditions
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Interventions
Allogeneic Mesenchymal Bone Marrow Cells
Biological
Lead sponsor
Stemedica Cell Technologies, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
2
States / cities
La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2022 · Synced Sep 6, 2026, 1:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Tau PET Imaging in the NACC Study Cohort

NCT03189485
View directory record Official record
Conditions
Normal Controls, MCI
Interventions
the radiotracer 18F-AV-1451
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
60 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Evaluating the Efficacy of DOSE Formulations in Treating Melasma and Cutaneous Signs of Aging

NCT04137263
View directory record Official record
Conditions
Melasma
Interventions
DOSE formulation
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of Tildrakizumab on Epigenetic Age

NCT05110313
View directory record Official record
Conditions
Psoriasis, Aging, Epigenetic Disorder, Inflammation; Skin
Interventions
TILDRAKIZUMAB
Biological
Lead sponsor
Carlos Wambier
Other
Eligibility
35 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 6, 2026, 1:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

NCT02530177
View directory record Official record
Conditions
Non-Metastatic Breast Cancer
Interventions
Clinical Assessments, Questionnaires, Saliva sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
546 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 6, 2026, 1:23 PM EDT
Enrolling by invitation Phase 4 Interventional Accepts healthy volunteers

MIBG in Aging and Neurologic Disorders

NCT05514106
View directory record Official record
Conditions
Lewy Body Disease, Dementia, Parkinsonism, Mild Cognitive Impairment, REM Sleep Behavior Disorder
Interventions
meta-iodobenzylguanidine (MIBG) (123I), 123I-MIBG scintigraphy
Drug · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of MetAP2 Inhibition on Bioenergetics and Aging-associated Characteristics in Adipose Tissue in Healthy Participants

NCT05989035
View directory record Official record
Conditions
Aging
Interventions
Abdominal subcutaneous adipose tissue biopsy
Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

How the Loss of Dopamine and Dopamine-Restoring Medicines Affect Movement Performance

NCT00040196
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 6, 2026, 1:23 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness

NCT05968144
View directory record Official record
Conditions
Prostatic Neoplasm, Survivorship, Frailty, Aging, Metastatic Breast Cancer
Interventions
Dietary recommendations, Time-restricted eating
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Aging and Risk for Alzheimer's Disease

NCT01962779
View directory record Official record
Conditions
Sleep Disordered Breathing, Alzheimer's Disease
Interventions
Continuous positive airway pressure (CPAP)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 6, 2026, 1:23 PM EDT
Recruiting Not applicable Interventional

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

NCT03906253
View directory record Official record
Conditions
Actinic Keratoses, Aging, Non-Melanoma Skin Cancer
Interventions
Fractionated Laser Resurfacing
Device
Lead sponsor
Wright State University
Other
Eligibility
60 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Clinical Study Evaluating the Safety and Effectiveness of the NIRA Laser M2.1 for the Treatment of Full-Face Wrinkles

NCT07572331
View directory record Official record
Conditions
Skin Ageing, Facial Wrinkles, Acne, Skin Elasticity, Infraorbital Dark Circle Severity, Skin Firmness, UV Spots, Skin Texture, Skin Pores, Brown Spots, Porphyrins, Red Spots
Interventions
NIRA Laser M2.1, Topical
Device · Other
Lead sponsor
NIRA Innovations Inc.
Industry
Eligibility
35 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Beverly, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Semaglutide Use in Elderly Obese Patients

NCT05302596
View directory record Official record
Conditions
Obesity, Aging
Interventions
Semaglutide Pen Injector
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aging, Exercise, and Hormonal Influences of Fat Metabolism

NCT00100451
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
exercise
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2001
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 6, 2026, 1:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Efudex Treatment on Photoaged Skin

NCT00121511
View directory record Official record
Conditions
Photo-aging, Keratosis
Interventions
Efudex (5-fluorouracil)
Drug
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 26, 2015 · Synced Sep 6, 2026, 1:23 PM EDT
Terminated No phase listed Observational

Risk Prediction of Taxane Chemotherapy-Induced Peripheral Neuropathy

NCT04932031
View directory record Official record
Conditions
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Aging
Interventions
Not listed
Lead sponsor
Sapere Bio
Industry
Eligibility
18 Years and older · Female only
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Birmingham, Alabama • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 6, 2026, 1:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Examine the Efficacy of a Supplement to Support Healthy Hair and Skin

NCT06579742
View directory record Official record
Conditions
Hair Thinning, Hair Loss
Interventions
Live Conscious Beyond Collagen, Placebo
Dietary Supplement
Lead sponsor
Scale Media Inc
Industry
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 6, 2026, 1:23 PM EDT