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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nosocomial Infections Clear all
Completed Not applicable Interventional Results available

Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection

NCT03349268
View directory record Official record
Conditions
Healthcare Associated Infection, Clostridium Difficile Infection, Infection Due to Multidrug Resistant Bacteria
Interventions
Pulsed xenon ultraviolet (PX-UV) Device, Sham Device
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
25,732 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Jul 22, 2026, 9:38 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

NO Prevention of COVID-19 for Healthcare Providers

NCT04312243
View directory record Official record
Conditions
Coronavirus Infections, Healthcare Associated Infection
Interventions
Inhaled nitric oxide gas
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2 Interventional Results available

Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Nosocomial Genotype 1 HCV Infection

NCT01924949
View directory record Official record
Conditions
Hepatitis C
Interventions
LDV/SOF
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2018 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2 Interventional Results available

Inulin for Infections in the Intensive Care Unit

NCT03865706
View directory record Official record
Conditions
Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders, Critical Illness, Sepsis
Interventions
Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 22, 2026, 9:38 AM EDT
Completed No phase listed Observational

Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice

NCT00617006
View directory record Official record
Conditions
Nosocomial Infections
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
Not listed
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 14, 2008 · Synced Jul 22, 2026, 9:38 AM EDT
Enrolling by invitation No phase listed Observational

Studies of the Human Microbiome in Clinical Center Patients

NCT01933620
View directory record Official record
Conditions
Multidrug-resistant Colonization
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
2 Years to 120 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 3 Interventional

Study Evaluating Tigecycline Versus Imipenem/Cilastatin in Hospital-Acquired Pneumonia

NCT00080496
View directory record Official record
Conditions
Bacterial Pneumonia
Interventions
Tigecycline, Imipenem, Cilastatin
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
430 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
29
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Martinez, California + 21 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2008 · Synced Jul 22, 2026, 9:38 AM EDT
Recruiting Not applicable Interventional

Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile

NCT05389904
View directory record Official record
Conditions
C. Difficile
Interventions
Arm 1: Routine care, Arm 2: Preemptive C. difficile infection prevention bundle
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

NCT00549393
View directory record Official record
Conditions
Nosocomial Infections
Interventions
2% Chlorhexidine gluconate cloth
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Months to 25 Years
Enrollment
5,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2 Interventional Results available

Strategies To Prevent Pneumonia 2 (SToPP2)

NCT00893763
View directory record Official record
Conditions
Infections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
Interventions
Pre-intubation CHX, Control
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 10, 2016 · Synced Jul 22, 2026, 9:38 AM EDT
Completed No phase listed Observational

Clinician Ability to Predict the Presence of Nosocomial Pneumonia Based on Bronchoscopic Findings

NCT01904305
View directory record Official record
Conditions
Pneumonia
Interventions
Not listed
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2013 · Synced Jul 22, 2026, 9:38 AM EDT
Terminated Phase 2 Interventional

Xylitol - Healthcare Associated Infection Reduction in Stem Cell Transplant Patients

NCT04117477
View directory record Official record
Conditions
Allogeneic Hematopoietic Cell Transplantation
Interventions
Xylitol, Placebo
Drug · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Jul 22, 2026, 9:38 AM EDT
Withdrawn Not applicable Interventional

Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients

NCT01858051
View directory record Official record
Conditions
Hypovitaminosis D
Interventions
Cholecalciferol, Placebo
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Not applicable Interventional Results available

Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit

NCT01640925
View directory record Official record
Conditions
Cross Infection, Pneumonia, Ventilator-associated, Catheter-related Infections, Infection Due to Indwelling Urinary Catheter, Surgical Wound Infection
Interventions
Chlorhexidine gluconate, Standard bathing
Drug · Other
Lead sponsor
Joshua Swan
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Jul 22, 2026, 9:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early Diagnosis of Candidiasis in Premature Infants

NCT00109525
View directory record Official record
Conditions
Infection, Candida, Candidiasis, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
3 Days to 120 Days
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
20
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 22, 2026, 9:38 AM EDT
Terminated Phase 2 Interventional Results available

Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

NCT01897792
View directory record Official record
Conditions
Coagulopathy, Nosocomial Pneumonia
Interventions
Vitamin C, Vitamin E, Saline (for Vitamin C), Placebo (for Vitamin E)
Dietary Supplement · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Not applicable Interventional Results available

Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections

NCT00779246
View directory record Official record
Conditions
Staphylococcal Infections
Interventions
Nasal swabs for MRSA culture, Chlorhexidine gluconate, Contact isolation
Other · Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
1,518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2 Interventional Results available

Vitamin D in Ventilated ICU Patients

NCT01372995
View directory record Official record
Conditions
Respiratory Failure
Interventions
Enteral Vitamin D3 50,000 IU, Enteral Vitamin D3 100,000IU, Inactive substance
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2017 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 2 Interventional

Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia

NCT01021436
View directory record Official record
Conditions
Pneumonia
Interventions
Amikacin inhalation solution (BAY41-6551)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
4
States / cities
Birminghan, Alabama • Cincinnati, Ohio • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Phase 4 Interventional

Daily Chlorhexidine Bathing and Infection Rates in Critically-ill Patients

NCT02033187
View directory record Official record
Conditions
Healthcare Associated Infections
Interventions
Chlorhexidine bathing, Non-chlorhexidine bathing
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Jul 22, 2026, 9:38 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Aerosolized and Intravenous Colistin in Healthy Adults

NCT01863719
View directory record Official record
Conditions
Pathogen Resistance, Pneumococcal Infection, Pneumonia
Interventions
Colistimethate sodium
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 45 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Baltimore, Maryland • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Jul 22, 2026, 9:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Volatile Organic Compounds in Staphylococcus Aureus Patients

NCT01379053
View directory record Official record
Conditions
Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus, Nosocomial Disease
Interventions
Not listed
Lead sponsor
Landon Pediatric Foundation
Other
Eligibility
1 Year to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2014 · Synced Jul 22, 2026, 9:38 AM EDT
Not listed No phase listed Observational

Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections

NCT00502476
View directory record Official record
Conditions
Nosocomial Bacteremia, MRSA Colonization, MRSA Infection, VRE Colonization, VRE Infection
Interventions
Bathing with Chlorhexidine Impregnated Washcloths
Procedure
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
14,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Chicago, Illinois • Iowa City, Iowa • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2007 · Synced Jul 22, 2026, 9:38 AM EDT
Completed Not applicable Interventional

Comparison of Standard Isolation With Targeted Isolation for Preventing Nosocomial Transmission of MRSA and VRE

NCT03268122
View directory record Official record
Conditions
MRSA, VRE Infection
Interventions
Standard Contact Isolation, Targeted Contact Isolation
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,974 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Jul 22, 2026, 9:38 AM EDT