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ClinicalTrials.gov public records Last synced Nov 5, 2026, 8:52 AM EST

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Showing 1–24 of 413 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: OA Knee Pain Clear all

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic
Interventions: Shoulder/Hip/Knee Embolization with Embozene Microspheres; Device
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 25 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Knee Osteoarthritis, Patellofemoral Pain (PFPS)
Interventions: WBCT; Radiation
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Osteo Arthritis Knee
Interventions: Active tDCS, Sham tDCS; Device
Lead sponsor: Florida State University; Other
Eligibility: 50 Years to 85 Years
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Knee Osteoarthritis
Interventions: Hylan G-F 20, Control; Device · Other
Lead sponsor: OhioHealth; Other
Eligibility: 40 Years to 70 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Osteoarthritis Of Knee
Interventions: Geniculate Artery Embolization; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Woodbridge, Virginia

Conditions: Knee Arthritis, Knee Osteoarthritis
Interventions: Suzetrigine; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Osteo Arthritis Knee
Interventions: Geniculate Artery Embolization, Sham Procedure; Device · Diagnostic Test
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Woodbridge, Virginia

Conditions: Osteoarthritis of the Knee
Interventions: 4 mL injection of Ampion, 4 mL injection of Placebo; Biological · Drug
Lead sponsor: Ampio Pharmaceuticals. Inc.; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
Interventions: Registry (N/A); Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Knee Osteoarthritis
Interventions: Low-carbohydrate diet; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 65 Years to 75 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Knee Osteoarthritis
Interventions: Arthroscopic debridement with stem cell transplantation, Arthroscopic debridement only; Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 35 Years to 70 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 3
States / cities: Santa Monica, California • Stanford, California • Denver, Colorado

Conditions: Knee Osteoarthritis
Interventions: canakinumab, LNA043, Placebo to canakinumab; Biological · Other
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 5
States / cities: La Mesa, California • Clearwater, Florida • Sunrise, Florida + 2 more

Conditions: Osteoarthritis of the Knee
Interventions: celecoxib, placebo; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 45 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Beachwood, Ohio

Conditions: Osteoarthritis Knee Pain
Interventions: Placebo, LY545694 49 mg, LY545694 105 mg; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 40 Years to 70 Years
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 5
States / cities: Spring Valley, California • DeLand, Florida • South Miami, Florida + 2 more

Conditions: Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
Interventions: Walking; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years to 80 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Osteoarthritis, Knee
Interventions: Amniotic Fluid, Saline Placebo; Other
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 30 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 4
States / cities: Birmingham, Alabama • Atlanta, Georgia • Des Plaines, Illinois + 1 more

Conditions: Knee Osteoarthritis
Interventions: Embosphere Microspheres; Device
Lead sponsor: University of Miami; Other
Eligibility: 40 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Knee Osteoarthritis
Interventions: Tai Chi, Physical Therapy; Behavioral
Lead sponsor: Tufts Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis
Interventions: Exercise and Dietary Weight Loss, Walk with Ease; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 50 Years and older
Enrollment: 227 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Osteoarthritis
Interventions: Lifestyle Behavioral Weight Management Program, Pain-Coping Skills Training, Standard Care; Behavioral · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 412 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Injuries, Knee Osteoarthritis
Interventions: Cutaneous Stimulation, Knee Sleeve; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Stanford, California

Conditions: Osteoarthritis, Knee Osteoarthritis
Interventions: Not listed
Lead sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); NIH
Eligibility: 45 Years to 79 Years
Enrollment: 4,796 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2015
U.S. locations: 5
States / cities: Baltimore, Maryland • Columbus, Ohio • Pittsburgh, Pennsylvania + 1 more

Conditions: Knee Osteoarthritis
Interventions: Reiki, Sham Reiki, Mindfulness Meditation; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Osteoarthritis (OA) of the Knee, Fear of Needles
Interventions: 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic; Procedure
Lead sponsor: University of California, Davis; Other
Eligibility: 40 Years to 89 Years
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Sacramento, California

Search by objective public record fields.

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

Pilot Study of Therapy With Hylan G-F 20 Exercise Capacity

Geniculate Artery Embolization for the Treatment of Knee Pain

Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty

Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA)

A Study to Evaluate Safety of Three Intra-articular Injections of Ampion in the Knee of Adults With Osteoarthritis Pain

Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis

A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)

Efficacy of Celecoxib 200mg in Relieving Pain and Walking Dysfunction in Osteoarthritis of the Knee

A Study in the Treatment of Osteoarthritis Knee Pain

Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis

Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Tai Chi and Physical Therapy for Knee Osteoarthritis

Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients

Weight Management and Coping Skills Training For Patients With Knee Osteoarthritis

Gait Modification Treatments for Knee Pathology

Osteoarthritis Initiative (OAI): A Knee Health Study

New Options for Treating Knee Osteoarthritis Pain

Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?