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ClinicalTrials.gov public records Last synced Oct 3, 2026, 11:23 PM EDT

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Showing 49–72 of 121 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obese Older Adults Clear all
Completed Phase 1 Interventional

Pharmacokinetic Properties of Lorcaserin in Obese or Overweight Elderly Subjects

NCT00828581
View directory record Official record
Conditions
Obesity
Interventions
lorcaserin
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Willingboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 3, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise and Protein Efficiency in T2D

NCT07477067
View directory record Official record
Conditions
Type 2 Diabetes, Control Condition
Interventions
12 week progressive exercise training
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Active, not recruiting Phase 4 Interventional

GLP-1s to Enhance Lasting Optimal Weight

NCT06861439
View directory record Official record
Conditions
Obesity
Interventions
Tirzepatide
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Disparities in Late Life Depression and Metabolic Syndrome

NCT01428791
View directory record Official record
Conditions
Depressive Symptoms, Metabolic Syndrome X, Overweight, Obesity, Hypertension, Hyperglycemia, Dyslipidemias
Interventions
Generations older adult membership program, BRIGHTEN Heart Virtual Team intervention
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
60 Years to 110 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Muscle for Functional Independence Trial

NCT01049698
View directory record Official record
Conditions
Obesity
Interventions
Resistance Training, Resistance Training + Diet
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
65 Years to 79 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Semaglutide Use in Elderly Obese Patients

NCT05302596
View directory record Official record
Conditions
Obesity, Aging
Interventions
Semaglutide Pen Injector
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Metformin Effect on Brain Function in Insulin Resistant Elderly People

NCT03733132
View directory record Official record
Conditions
Insulin Resistance, Obesity, Obesity, Abdominal
Interventions
Metformin Hydrochloride, Placebo Oral Tablet
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 3, 2026, 11:23 PM EDT
Recruiting Not applicable Interventional

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571
View directory record Official record
Conditions
Obesity, Multiple Chronic Conditions
Interventions
Prescriptive, Behavioral
Other · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 3 Interventional Results available

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

NCT04966741
View directory record Official record
Conditions
Bardet-Biedl Syndrome, POMC Deficiency Obesity, PCSK1 Deficiency Obesity, LEPR Deficiency Obesity
Interventions
Setmelanotide
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
2 Years to 5 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Aurora, Colorado • New York, New York • Marshfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition Intervention to Measure Metabolic Response in Children

NCT03139773
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Control Breakfast Beverage, Omega-3 Breakfast Beverage
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
8 Years to 12 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Predictors of the Metabolic Effect of Sleep Loss

NCT00965783
View directory record Official record
Conditions
Apnea, Obstructive Sleep Apnea (OSA), Obesity
Interventions
Restriction, Extension
Other
Lead sponsor
University of Chicago
Other
Eligibility
25 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lean and Obese: Dietary Inflammation

NCT05327868
View directory record Official record
Conditions
Obesity, Inflammation, Dietary Fat
Interventions
Low Fat Diet (LFD), High Fat Diet (HFD)
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years to 79 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postprandial Inflammation and Nuts (PIN) in Older Adults

NCT06348771
View directory record Official record
Conditions
Healthy Aging, Overweight and Obesity
Interventions
monounsaturated fatty acids (MUFA) peanut meal
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
55 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HealthyWE: Achieving a Healthy Weight and Reducing Pain

NCT07095673
View directory record Official record
Conditions
Obesity &Amp; Overweight
Interventions
HealthyWE
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
19 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

NCT00119795
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Metabolic Syndrome X, Obesity
Interventions
Exercise, Weight Loss, Health Education Control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Greensboro, North Carolina • Lexington, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 1 Interventional

A Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 Years

NCT02696148
View directory record Official record
Conditions
Metabolism and Nutrition Disorder, Obesity
Interventions
liraglutide, placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
7 Years to 11 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
9
States / cities
Anaheim, California • New Haven, Connecticut • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Oct 3, 2026, 11:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

MOWI Amulet Mobile Health Technology Validation

NCT03085589
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

I-STAND R21: Reducing Sedentary Time in Older Adults

NCT02692560
View directory record Official record
Conditions
Obesity, Sedentary Lifestyle
Interventions
I-STAND, Healthy Living
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
60 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Cognitive Function in Adults

NCT03685305
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Hypocaloric diet with hunger reduction strategy, Hypocaloric diet without hunger reduction strategy
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 3, 2026, 11:23 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Telenutrition Center: Examining the Implementation of Behavioral Therapy for Obesity

NCT03855566
View directory record Official record
Conditions
Obesity
Interventions
Intensive behavioral therapy for obesity
Behavioral
Lead sponsor
University of Southern Mississippi
Other
Eligibility
25 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Patient Coach Support for Older Adults With Obesity

NCT06624163
View directory record Official record
Conditions
Obesity
Interventions
OHWL Clinic Activities (Standard of Care), Coach Activities
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 3, 2026, 11:23 PM EDT
Completed No phase listed Observational

Dose-Response to Exercise in Women Aged 45-75 Years (DREW)

NCT00011193
View directory record Official record
Conditions
Cardiovascular Diseases, Hypertension, Postmenopausal, Overweight or Obese
Interventions
Exercise
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Higher Protein Diet and Exercise for Optimal Weight Loss in Elderly Women

NCT00912210
View directory record Official record
Conditions
Bone and Body Composition, Obesity, Metabolic Syndrome, Physical Function, Quality of Life
Interventions
Whey protein isolate, Maltodextrin powder supplement
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
60 Years to 80 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2009 · Synced Oct 3, 2026, 11:23 PM EDT
Completed Phase 3 Interventional

Weight Loss and Exercise in Physically Limited Obese Elderly Subjects

NCT00146133
View directory record Official record
Conditions
Obesity, Frailty, Elderly
Interventions
diet, exercise
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2006 · Synced Oct 3, 2026, 11:23 PM EDT