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ClinicalTrials.gov public records Last synced Oct 8, 2026, 2:17 AM EDT

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Showing 73–96 of 121 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obese Older Adults Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Using Video Gaming to Evaluate Front of Pack Labeling With Children

NCT03482336
View directory record Official record
Conditions
Child Obesity
Interventions
Four FOP label designs
Other
Lead sponsor
Michigan State University
Other
Eligibility
6 Years to 10 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional

A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women

NCT02033655
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Protein supplementation, Diet counseling and group education lessons
Dietary Supplement · Behavioral
Lead sponsor
Duke University
Other
Eligibility
45 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Acute Exercise on Brain Insulin Sensitivity

NCT05853913
View directory record Official record
Conditions
Aging, Obesity, Insulin Resistance, Cognition, Cardiovascular Disease Risk
Interventions
Exercise
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
New Brunswick, New Jersey • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Phase 3 Interventional Results available

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

NCT04966741
View directory record Official record
Conditions
Bardet-Biedl Syndrome, POMC Deficiency Obesity, PCSK1 Deficiency Obesity, LEPR Deficiency Obesity
Interventions
Setmelanotide
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
2 Years to 5 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Aurora, Colorado • New York, New York • Marshfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postprandial Inflammation and Nuts (PIN) in Older Adults

NCT06348771
View directory record Official record
Conditions
Healthy Aging, Overweight and Obesity
Interventions
monounsaturated fatty acids (MUFA) peanut meal
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
55 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 8, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571
View directory record Official record
Conditions
Obesity, Multiple Chronic Conditions
Interventions
Prescriptive, Behavioral
Other · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause

NCT02404792
View directory record Official record
Conditions
HIV, Inflammation, Obesity, Aging, Biological
Interventions
High-intensity cardiovascular and resistance exercise, Moderate-intensity cardiovascular and resistance exercise
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 75 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome

NCT06025357
View directory record Official record
Conditions
Metabolic Syndrome, Menopause
Interventions
L-Citrulline supplementation, Placebo
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
45 Years to 79 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old

NCT01797042
View directory record Official record
Conditions
Obesity
Interventions
Dietary Compliance
Behavioral
Lead sponsor
Rippe Lifestyle Institute
Industry
Eligibility
20 Years to 60 Years
Enrollment
366 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Sep 30, 2014 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arthritis Pilot for Preserving Muscle While Losing Weight

NCT02239939
View directory record Official record
Conditions
Obesity, Osteoarthritis
Interventions
Vest, Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 79 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 8, 2026, 2:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Influence of Aerobic Training and Weight Loss on Skeletal Muscle Inflammatory Markers and Muscle Protein Balance in Older Adults

NCT03743675
View directory record Official record
Conditions
Overweight and Obesity, Inflammation; Muscle, Sedentary Lifestyle
Interventions
Diet-Induced Weight Loss, Aerobic Exercise Training
Behavioral
Lead sponsor
Miami University
Other
Eligibility
58 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Oxford, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 8, 2026, 2:17 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Metabolic Syndrome in an Elderly Population is More Linked to Insulin Resistance Than to Obesity

NCT00873964
View directory record Official record
Conditions
Metabolic Syndrome in the Elderly
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
60 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 30, 2012 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Launch II: A Pilot Randomized Control Trial of a Clinic and Clinic Plus Home Intervention for Preschool Obesity

NCT01419951
View directory record Official record
Conditions
Obesity
Interventions
Clinic + Home Behavioral Intervention, Pediatrician Counseling, Clinic Only Behavioral Intervention
Behavioral · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
2 Years to 5 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 22, 2014 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Weight Loss With Risedronate for Bone Health

NCT03411902
View directory record Official record
Conditions
Bariatric Surgery Candidate, Bone Loss, Weight Loss
Interventions
Risedronate Sodium 150 MG, Placebo
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 79 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Disparities in Late Life Depression and Metabolic Syndrome

NCT01428791
View directory record Official record
Conditions
Depressive Symptoms, Metabolic Syndrome X, Overweight, Obesity, Hypertension, Hyperglycemia, Dyslipidemias
Interventions
Generations older adult membership program, BRIGHTEN Heart Virtual Team intervention
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
60 Years to 110 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 8, 2026, 2:17 AM EDT
Completed No phase listed Observational Results available

Assessment of Body Composition and Physical Function

NCT05784571
View directory record Official record
Conditions
Body Composition, Physical Function
Interventions
Body Composition Assessment, Modified Physical Performance Test, Hand grip strength, 6-minute walk test, Measurement of blood glucose and insulin
Other · Procedure
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
60 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 8, 2026, 2:17 AM EDT
Recruiting Phase 2 Interventional

Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults

NCT06811324
View directory record Official record
Conditions
Obesity Prevention, Sarcopenia in Elderly, Cardiovascular Function, GLP - 1, Weight Loss
Interventions
Tirzepatide
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Utilizing Protein During Weight Loss to Impact Physical Function and Bone

NCT03819478
View directory record Official record
Conditions
Obesity, Weight Loss, Diet Modification, Aging, Weight Change, Body, Dietary Habits, Osteopenia, Osteoporosis, Bone Loss, Fractures, Bone
Interventions
Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement, 6-month NutraBio™ 100% Whey Protein Isolate Supplement, 18-month NutraBio™ 100% Whey Protein Isolate Supplement
Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 8, 2026, 2:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men

NCT02532725
View directory record Official record
Conditions
Obesity, Gender, Problem of Aging
Interventions
Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation, Pre-Exercise Risk Assessment
Procedure
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
35 Years to 55 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1972
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Addressing Place and People Micro Environments in Weight Loss Disparities

NCT03083964
View directory record Official record
Conditions
Obese
Interventions
Usual Care, Priming
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
35 Years to 64 Years · Female only
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 8, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise and Protein Efficiency in T2D

NCT07477067
View directory record Official record
Conditions
Type 2 Diabetes, Control Condition
Interventions
12 week progressive exercise training
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Time Restricted Eating for Metabolic and Psychological Optimization

NCT05997316
View directory record Official record
Conditions
Mild Cognitive Impairment, Obesity
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Phase 3 Interventional

Weight Loss and Exercise in Physically Limited Obese Elderly Subjects

NCT00146133
View directory record Official record
Conditions
Obesity, Frailty, Elderly
Interventions
diet, exercise
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2006 · Synced Oct 8, 2026, 2:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lean and Obese: Dietary Inflammation

NCT05327868
View directory record Official record
Conditions
Obesity, Inflammation, Dietary Fat
Interventions
Low Fat Diet (LFD), High Fat Diet (HFD)
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years to 79 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 8, 2026, 2:17 AM EDT