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ClinicalTrials.gov public records Last synced Oct 8, 2026, 5:36 PM EDT

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Showing 121–144 of 250 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obesity, Morbid Clear all
Completed Phase 4 Interventional Results available

Efficacy Of Quadratus Lumborum II Block For Laparoscopic Sleeve Gastrectomy

NCT04073056
View directory record Official record
Conditions
Morbid Obesity, High BMI
Interventions
Bupivacaine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Phase 3 Interventional Results available

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

NCT03746522
View directory record Official record
Conditions
Bardet Biedl Syndrome (BBS), Alström Syndrome (AS)
Interventions
Setmelanotide, Placebo
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
6 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
6
States / cities
San Diego, California • Springfield, Massachusetts • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Activity Level Monitoring Study

NCT05379088
View directory record Official record
Conditions
Obesity, Morbid Obesity
Interventions
Phone/zoom calls
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 8, 2026, 5:36 PM EDT
Withdrawn No phase listed Observational

Adjustable Gastric Band Survey Study

NCT01041534
View directory record Official record
Conditions
Morbid Obesity
Interventions
Survey
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 8, 2026, 5:36 PM EDT
Terminated No phase listed Observational

Obesity and Memory, mRNA, Body Composition, Comorbidity Scale

NCT00531505
View directory record Official record
Conditions
Obesity, Memory Deficits
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 16, 2015 · Synced Oct 8, 2026, 5:36 PM EDT
Completed No phase listed Observational

The Effect of Sleeve Gastrectomy on Food Preference

NCT02124993
View directory record Official record
Conditions
Severe Obesity
Interventions
Questionnaire
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Oct 8, 2026, 5:36 PM EDT
Completed No phase listed Observational

Laparoscopic Revision of Vertical Banded Gastroplasty to Gastric Bypass

NCT01041131
View directory record Official record
Conditions
Clinically Severe Obesity, Inadequate Weight Loss, Obesity Recidivism
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Jan 1, 2010 · Synced Oct 8, 2026, 5:36 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional

GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial

NCT06162715
View directory record Official record
Conditions
Severe Obesity, Obesity, BMI Greater Than 30
Interventions
Tirzepatide, Standard of Care post-gastric bypass
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 8, 2026, 5:36 PM EDT
Terminated No phase listed Observational

Obesity and Weight Loss on Reproductive Function

NCT00143078
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2015 · Synced Oct 8, 2026, 5:36 PM EDT
Terminated Not applicable Interventional

Esophageal Balloon Guided Weaning of the Morbidly Obese Patient

NCT02323009
View directory record Official record
Conditions
Morbid Obesity
Interventions
Esophageal Balloon, Cstat
Device · Other
Lead sponsor
East Carolina University
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Study of Weight Loss Using Gastric Stimulation in Obese Patients With Type 2 Diabetes

NCT00200018
View directory record Official record
Conditions
Severe to Morbid Obesity and Type 2 Diabetes
Interventions
Enterra Therapy System (H9900014)
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
2
States / cities
La Jolla, California • Eagan, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2009 · Synced Oct 8, 2026, 5:36 PM EDT
Terminated Phase 3 Interventional Results available

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy

NCT04741074
View directory record Official record
Conditions
CKD, Diabetic Kidney Disease, Type 2 Diabetes Mellitus in Obese, Obesity, Severe Obesity
Interventions
Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution, Placebo 1.5 ml, prefilled pen-injector for subcutaneous injection solution
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Danville, Pennsylvania • Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Phase 1 Interventional Results available

Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients

NCT05537883
View directory record Official record
Conditions
Morbid Obesity, Bariatric Surgery Candidate
Interventions
Liposomal bupivacaine, Bupivacaine Injection
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 8, 2026, 5:36 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Study of Proton Pump Inhibitors (PPI) to Prevent Strictures After Gastric Bypass Surgery

NCT00361985
View directory record Official record
Conditions
Anastomotic Stricture, Morbid Obesity
Interventions
Esomeprazole
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 8, 2026, 5:36 PM EDT
Not listed Phase 2Phase 3 Interventional

The Effects of Exenatide After Gastric Restriction

NCT00872378
View directory record Official record
Conditions
Morbid Obesity
Interventions
Exenatide, Placebo
Drug
Lead sponsor
Advanced Specialty Care
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Bend, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 31, 2009 · Synced Oct 8, 2026, 5:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Safety and Feasibility of ActivSightTM in Human

NCT04633512
View directory record Official record
Conditions
Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid, Inflammatory Bowel Diseases
Interventions
ActivSight
Device
Lead sponsor
Activ Surgical
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
3
States / cities
Buffalo, New York • Houston, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Phase 3 Interventional

Laparoscopic Sleeve Gastrectomy With and Without Omentectomy

NCT00434525
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic restrictive procedure, Sleeve gastrectomy
Procedure
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2009 · Synced Oct 8, 2026, 5:36 PM EDT
Terminated Not applicable Interventional Results available

Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclampsia

NCT03222414
View directory record Official record
Conditions
Pre-Eclampsia, Morbid Obesity, Parturient, Blood Pressure
Interventions
Non-invasive BP recording with conical Ultracheck Curve BP cuff, Non-invasive BP recording with traditional cylindrical BP cuff, Direct invasive arterial pressure
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 8, 2026, 5:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery

NCT04644445
View directory record Official record
Conditions
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
Interventions
Bariatric Full Liquid Diet
Dietary Supplement
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Oct 8, 2026, 5:36 PM EDT
Recruiting Phase 4 Interventional

Impact GLP-1 Agonists Following Bariatric

NCT06132477
View directory record Official record
Conditions
Morbid Obesity, Metabolic Syndrome, Diabetes Mellitus, Hypertension, Obstructive Sleep Apnea of Adult
Interventions
GLP-1 receptor agonist
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision

NCT04165694
View directory record Official record
Conditions
Bariatric Surgery Candidate, Severe Obesity
Interventions
Single Anastomosis Duodenal Ileal Bypass (SADI)
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Comparison of Weight Loss Programs for Individuals With Severe Obesity

NCT01330329
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Standard behavioral treatment, SBT + technology system (SBT+FIT)
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 20, 2012 · Synced Oct 8, 2026, 5:36 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Comparison of Esophageal Manometry and CT Scan Measurements

NCT04213911
View directory record Official record
Conditions
Morbid Obesity, Respiratory Failure
Interventions
low-dose chest CT scan, insertion of esophageal balloon
Radiation · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 8, 2026, 5:36 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of RM-493 on Energy Expenditure in Obese Individuals

NCT01867437
View directory record Official record
Conditions
Obesity, Morbid Obesity
Interventions
Placebo, RM-493
Drug
Lead sponsor
Rhythm Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 8, 2026, 5:36 PM EDT