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Showing 1–24 of 184 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obesity, Primary Clear all
Completed Not applicable Interventional

Examining Reach and Implementation of an Evidence-based Weight Loss Program in Rural Primary Care

NCT03690557
View directory record Official record
Conditions
Obesity
Interventions
IncentaHealth
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
David City, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional

Use of Electronic Health Records for Addressing Overweight and Obesity in Primary Care

NCT01480466
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Obesity tools in the electronic health record
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years and older
Enrollment
65,278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2014 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Varying the Energy Density and Portion Size of the Main Course After a First-course Salad

NCT01729390
View directory record Official record
Conditions
Obesity
Interventions
Energy density and portion size feeding study
Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Binge Eating in Obese Patients in Primary Care

NCT00537810
View directory record Official record
Conditions
Obesity, Binge Eating
Interventions
Sibutramine, Placebo, Self-help CBT + Sibutramine, Self-help CBT + Placebo
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Sep 9, 2026, 11:51 PM EDT
Recruiting Phase 2 Interventional

Uterine Preservation Via Lifestyle Transformation

NCT05903131
View directory record Official record
Conditions
Endometrial Hyperplasia, Grade 1 Endometrial Cancer
Interventions
Telemedicine behavioral weight intervention, Progestin, Enhanced usual care, Levonorgestrel-releasing IUD.
Behavioral · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
3
States / cities
St Louis, Missouri • Albuquerque, New Mexico • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partnership Optimizes Weight Management in Primary Care

NCT02959021
View directory record Official record
Conditions
Obesity
Interventions
weight loss intervention - self directed, weight loss intervention - peer coach
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 75 Years
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional

Smart and Secure Children Program for Preschool Obesity

NCT02681874
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
SSC Program, Written Handouts
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
2 Years to 5 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Primary Care Pediatrics Learning Activity and Nutrition With Families

NCT02873715
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Family-based treatment, Usual Care
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
6 Years and older
Enrollment
1,010 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Buffalo, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Sep 9, 2026, 11:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Muscle OXPHOS and Nutrient Homeostasis

NCT02920671
View directory record Official record
Conditions
Mitochondrial Diseases, Obesity
Interventions
Tracer-enhanced oral glucose tolerance test (OGTT*), Muscle MRI, Dual energy x-ray absorptiometry (DXA), Questionnaires
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Results available

Promoting Successful Weight Loss in Primary Care in Louisiana

NCT02561221
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 75 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 9, 2026, 11:51 PM EDT
Recruiting No phase listed Observational

International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation (ROHHAD) Registry

NCT03135730
View directory record Official record
Conditions
ROHHAD, Rapid-Onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation
Interventions
ROHHAD
Genetic
Lead sponsor
Ilya Khaytin
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2039
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional

Endoscopic Gastric Mucosal Ablation as a Primary Obesity Therapy

NCT05486338
View directory record Official record
Conditions
Obesity, Adiposity
Interventions
Hybrid Argon Plasma Coagulation (HAPC)
Device
Lead sponsor
Erbe Elektromedizin GmbH
Industry
Eligibility
22 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida • Cary, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Enrolling by invitation No phase listed Observational

Group Medical Appointments for Intensive Lifestyle Treatment for Obesity in Cleveland Clinic Primary Care Practices

NCT07268417
View directory record Official record
Conditions
Obesity & Overweight
Interventions
ACTIVATE OC
Other
Lead sponsor
Anita Misra-Hebert
Other
Eligibility
20 Years to 75 Years
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional

Text Messaging for Weight Loss

NCT01736111
View directory record Official record
Conditions
Obesity
Interventions
one way text, Personal feedback
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2015 · Synced Sep 9, 2026, 11:51 PM EDT
Terminated Phase 1 Interventional

Diazoxide Suppression Test P&F Study

NCT06606327
View directory record Official record
Conditions
Insulin Resistance, Hyperinsulinemia, Obesity
Interventions
Diazoxide, 3 mg/kg per dose
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Active, not recruiting Not applicable Interventional

Weight Loss Clinical Decision Support

NCT05198765
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
BMI-CDS
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
10,120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Completed No phase listed Observational

Primary Care, Communication, and Improving Children's Health

NCT02277899
View directory record Official record
Conditions
Childhood Obesity, Overweight, Communication, Weight Loss
Interventions
Communication regarding overweight status, Risk-factor assessment and counseling, Lifestyle behavior assessment and counseling, Interval follow-up to readdress weight, Patient-centered communication
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 9, 2026, 11:51 PM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telecoaching Plus a Portion Control Device for Weight Management in the Primary Care Setting

NCT02373878
View directory record Official record
Conditions
Obesity
Interventions
Telecoaching plus Plate, Usual Care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Sep 9, 2026, 11:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pediatric Primary Hypertension and the Renin-Angiotensin System (PHRAS)

NCT03310684
View directory record Official record
Conditions
Pediatric Disorder, Pediatric Obesity, Primary Hypertension
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
5 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 9, 2026, 11:51 PM EDT
Enrolling by invitation Not applicable Interventional

Using Online Tools to Increase Weight Loss in Primary Care

NCT06928571
View directory record Official record
Conditions
Obesity
Interventions
Connect4Health Engage, Connect4Health Discover
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
473 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Healthy Sleeping and Feeding During Infancy

NCT00125580
View directory record Official record
Conditions
Obesity
Interventions
Infant sleep instruction
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
2
States / cities
Hershey, Pennsylvania • University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional

Better Weight-Better Sleep (BWBS) Trial

NCT00979784
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Better Weight, Better Weight & Better Sleep
Behavioral
Lead sponsor
Summa Health System
Other
Eligibility
18 Years to 84 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2013 · Synced Sep 9, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WOOP VA: Promoting Weight Management in Primary Care

NCT05014984
View directory record Official record
Conditions
Obesity
Interventions
mental contrasting with implementation intentions, telephone-delivered, telehealth-delivered, and or in-person MOVE! or TeleMOVE!, Information About Diet, Physical Activity, and Weight Management (Baseline Visit - 10 minutes): All, Telephone MCII Check-ins (30 minutes at 3 days, 4 weeks, and 2 months after baseline visit)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 9, 2026, 11:51 PM EDT