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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:31 PM EDT

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Showing 1–24 of 5,566 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obesity & Overweight Clear all
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Regional Lipolysis Insulin Regulation

NCT06392854
View directory record Official record
Conditions
Obesity
Interventions
Insulin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pre-Pregnancy Weight Loss and Baby Behavior Study

NCT06358729
View directory record Official record
Conditions
Obesity; Familial, Pregnancy Related, Infant Behavior
Interventions
Typical Nipple, Challenging Nipple
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
3 Months and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional

Examining Self-tracking Behaviors in a Mobile Intervention for Binge Eating and Weight Management

NCT04711577
View directory record Official record
Conditions
Obesity, Binge Eating
Interventions
Track clinician-determined symptoms, Track clinician-determined and self-determined symptoms
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women

NCT01868230
View directory record Official record
Conditions
Diabetes
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Maternal Metabolic and Molecular Changes Induced by Preconception Weight Loss and Their Effects on Birth Outcomes

NCT03244722
View directory record Official record
Conditions
Obesity; Familial, Pregnancy Related
Interventions
Very-low energy Diet (VLED), Standard of care (SOC)
Dietary Supplement · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Active, not recruiting No phase listed Observational

Evaluating the Health Outcomes of the Joslin Why WAIT Program

NCT01937845
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 90 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children

NCT00108901
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 11 Years
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2014 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Social Media-based Weight Loss Program for Low Socioeconomic Status Individuals

NCT03337230
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity, Diet, Social Support
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
35 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Metabolic Effects of Different Weight Loss Diets

NCT00422630
View directory record Official record
Conditions
Metabolic Syndrome X, Obesity, Insulin Resistance, Hypertension, Diabetes
Interventions
The DASH diet, The low glycemic Index Diet, Reduced calorie American Diet
Behavioral
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2011 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 3 Interventional Results available

Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity

NCT03552757
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Semaglutide 1.0 mg, Semaglutide 2.4 mg, Placebo I (Semaglutide), Placebo II (Semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
1,210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
50
States / cities
Buena Park, California • Concord, California • Fresno, California + 42 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 1 Interventional

A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

NCT02128581
View directory record Official record
Conditions
Obesity, Diabetes, Roux-en-Y Gastric Bypass
Interventions
Exendin-9,39, Saline
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 2 Interventional

NEW DAY: Nutrition, Exercise, Weight Loss, Diabetes And You

NCT00007800
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Behavioral Group Weight Loss Intervention, Motivational Interviewing
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
19 Years and older · Female only
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 14, 2010 · Synced Oct 23, 2026, 6:31 PM EDT
Recruiting Not applicable Interventional

Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity

NCT07091500
View directory record Official record
Conditions
Obesity, Skeletal Muscle, Brain Connectivity
Interventions
Exercise training, Semaglutide, Therapy Cessation
Behavioral · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Recruiting Not applicable Interventional

Brief Inhibitory Training for Eating - Intervention

NCT07592728
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Daily inhibitory control training
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
14 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional

Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness

NCT01307644
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Experimental: Web-based only (WO) weight intervention, Experimental: WO plus peer-led discussion board (WD), Experimental: WO & professional email counseling (WE)
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 23, 2026, 6:31 PM EDT
Active, not recruiting Not applicable Interventional

PA Moves Trial - Patient Participants

NCT05227105
View directory record Official record
Conditions
Overweight or Obesity, Diabetes Mellitus, Type 2, Physical Inactivity
Interventions
Physical Activity, Delayed intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Mindfulness Intervention

NCT01974102
View directory record Official record
Conditions
Parental Stress, Parent and Child Stress, Parental and Child Obesity, Child Obesity
Interventions
Lifestyle counseling, Parenting Mindfully for Health (PMH)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
2 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 6, 2021 · Synced Oct 23, 2026, 6:31 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Reduce Obesity and Diabetes

NCT00954577
View directory record Official record
Conditions
Type 2 Diabetes, Pediatric Obesity, Dyslipidemia
Interventions
Nutrition, health, and exercise education
Behavioral
Lead sponsor
Academy for Medical Development and Collaboration, New York
Other
Eligibility
10 Years to 15 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
5
States / cities
Brooklyn, New York • Manhasset, New York • Mineola, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2009 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program

NCT04514900
View directory record Official record
Conditions
Obesity
Interventions
Video Chat +Personalized Feedback, Video Chat + Basic Feedback, Discussion Board for Social Support +Basic Feedback, Discussion Board for Social Support+Personalized Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 3 Interventional

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

NCT06588283
View directory record Official record
Conditions
Psoriasis, Obesity
Interventions
Ixekizumab, Tirzepatide
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
68
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Phase 2 Interventional Results available

Effects of Human Leptin Replacement

NCT00657605
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Diabetes
Interventions
Recombinant methionyl human leptin
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 23, 2026, 6:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Red Light LED Therapy on Body Contouring

NCT03470272
View directory record Official record
Conditions
Obesity
Interventions
FB Professional LED Red light therapy, Effects of Red Light LED Therapy on Body Contouring
Device
Lead sponsor
Manamed Inc.
Industry
Eligibility
18 Years to 77 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New Port Richey, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder

NCT03604172
View directory record Official record
Conditions
Binge Eating Disorder, Overweight and Obesity
Interventions
Cognitive behavioral therapy, Waitlist
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 23, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vitamin D and Vascular Health in Children

NCT01797302
View directory record Official record
Conditions
Obesity, Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 18 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 23, 2026, 6:31 PM EDT