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ClinicalTrials.gov public records Last synced Oct 28, 2026, 6:29 AM EDT

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Showing 289–312 of 367 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive - Compulsive Disorder Clear all
Completed Not applicable Interventional

Online Response Inhibition Training for Trichotillomania

NCT01984333
View directory record Official record
Conditions
Trichotillomania
Interventions
Online cognitive training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
8 Years to 17 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 28, 2026, 6:29 AM EDT
Withdrawn Not applicable Interventional

Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD)

NCT03767491
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Smartphone-delivered CBT for OCD
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Not applicable Interventional

Adjunctive Glycine for Obsessive Compulsive Disorder

NCT00405535
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
glycine, placebo
Drug · Other
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2016 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 2 Interventional Results available

Epidiolex in Obsessive Compulsive Disorder and Related Disorders

NCT04978428
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
Interventions
Cannabidiol
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)

NCT03459456
View directory record Official record
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Provocation OC task (Provoc), Trier Social Stress Test (TSST), Exposure provocation task
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

NCT04031469
View directory record Official record
Conditions
Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Alzheimer Disease, Alzheimer Dementia (AD), Alzheimer Dementia, Alzheimer Disease (AD), Crohn, Crohn Colitis, Crohn Disease (CD), Crohn Disease Colon, Myalgic Encephalomyelitis, ME/CFS, Myalgic Encephalomyelitis (ME), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Psoriasis, Psoriasis Annularis, Psoriasis Chronic, Chronic Urinary Tract Infection, Ulcerative Colitis (Disorder), Ulcerative Colitis (UC), Ulcerative Colitis Acute, Ulcerative Colitis Chronic, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Constipation Chronic Idiopathic, Constipation, Celiac, Celiac Disease, Celiac Sprue, Lyme Arthritis, Lyme Borreliosis, Nervous System, Lyme Disease, Chronic, Cholesterol, Cholesterol Level, High, Cancer, Colon Cancer, Amyotrophic Lateral Sclerosis (ALS), Amyotrophic Lateral Sclerosis, Rheumatoid Arthritis (RA), Rheumatoid Arthritis - Rheumatism, Chronic Fatigue Syndrome (CFS), PARKINSON DISEASE (Disorder), Parkinson Disease, Parkinson Disease (PD), Depression, Major Depressive Disorder (MDD), Depression Disorder, Depression in Adults, Anxiety, Anxiety Disorder Generalized, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Disorder OCD, Obsessive - Compulsive Disorder, Bipolar, Bipolar 1 Disorder, Bipolar Disorder (BD), Bipolar Disorder I and II, Bipolar and Related Disorders, Migraine, Migraine Disorder, Diabetes (DM), Diabetes, Lupus, Lupus Erythematosus, Epidermolysis Bullosa (EB), Mesothelioma, Mesothelioma Malignant, IBS (Irritable Bowel Syndrome), Irritable Bowel, IBS - Irritable Bowel Syndrome, Irritable Bowel Syndrome (IBS), Eczema, Eczema Atopic Dermatitis, Acne, Myasthaenia Gravis, Gout
Interventions
There is no intervention in this study
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
12 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Radical Openness for Adolescents Pilot

NCT05913557
View directory record Official record
Conditions
Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
Interventions
Radically Open Dialectical Behavior Therapy (RO DBT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 2 Interventional

A Study in Patients With Trichotillomania

NCT03797521
View directory record Official record
Conditions
Trichotillomania
Interventions
SXC-2023, Placebo
Drug
Lead sponsor
Promentis Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
13
States / cities
Pico Rivera, California • Riverside, California • North Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 2 Interventional Results available

N-Acetyl Cysteine in Pathologic Skin Picking

NCT01063348
View directory record Official record
Conditions
Pathologic Skin Picking, Neurotic Excoriation, Psychogenic Excoriation, Dermatillomania
Interventions
N-Acetyl Cysteine, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 4 Interventional

Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00116532
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2007 · Synced Oct 28, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation

NCT06596447
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Neuromodulation
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
22 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Technology Assisted Treatment for Trichotillomania

NCT05118633
View directory record Official record
Conditions
Trichotillomania
Interventions
Keen2 bracelet, Reminder bracelet, Keen2 app, Health Reminders App
Device · Behavioral
Lead sponsor
HabitAware Inc.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Rehab and Exposure Treatment for Hoarding

NCT02402647
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Treatment (CREST), Exposure Therapy (ET)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Not applicable Interventional

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders

NCT01243606
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders
Interventions
Single Diagnosis Treatment Protocol, Unified Protocol (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Not applicable Interventional Results available

Dextro-Amphetamine Versus Caffeine in Treatment-resistant OCD

NCT00363298
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
dextro-amphetamine, Sham Comparison
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Not applicable Interventional

An Evaluation of the Safety and Efficacy of the dTMS Treatment for OCD

NCT02229903
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Active DTMS Treatment, Sham Treatment
Device
Lead sponsor
Brainsway
Industry
Eligibility
22 Years to 68 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
10
States / cities
Los Angeles, California • San Diego, California • Gainesville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 4 Interventional

Predicting Treatment Response in Patients With OCD

NCT03993535
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
selective serotonin reuptake inhibitor
Drug
Lead sponsor
University of Sao Paulo
Other
Eligibility
18 Years to 50 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 2 Interventional Results available

Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)

NCT02062658
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Ketamine, Exposure and Response Prevention
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 28, 2026, 6:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 28, 2026, 6:29 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Marijuana on Symptoms of OCD

NCT03274440
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cannabis, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 28, 2026, 6:29 AM EDT
Terminated Phase 4 Interventional Results available

Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS

NCT04015596
View directory record Official record
Conditions
PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive Disorder
Interventions
Naproxen Sodium, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 15 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

OCD LIFU Target Engagement

NCT07558148
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Neural Mechanisms of Response Inhibition Training for OCRD

NCT05377125
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Tricholemmoma, Skin-Picking
Interventions
Computerized cognitive training, Computerized placebo training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 28, 2026, 6:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Serotonin Transporters in Obsessive-Compulsive-Related Disorders

NCT00082550
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 28, 2026, 6:29 AM EDT