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Showing 1–24 of 449 matching trials from the live ClinicalTrials.gov search.
Conditions
Nicotine Use Disorder, Smoking Cessation, Smoking Cessation Intervention
Interventions
Enhanced Courage to Quit
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem, Emotional Disorder
Interventions
Unified Protocol for Emotional Disorders in Adolescents (UP-A)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Coral Gables, Florida
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and response prevention therapy
Behavioral
Lead sponsor
NOCD
Industry
Eligibility
10 Years and older
Enrollment
2,069 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Accepts healthy volunteers

Cue Induced Imaging in Nicotine Dependent Smokers

NCT00844701
Conditions
Nicotine Dependence
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional

Skin Picking Approach Avoidance Task

NCT04099537
Conditions
Skin-Picking
Interventions
Computerized cognitive training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Obsessive-Compulsive Disorder
Interventions
Personalized Assessments, Standard of Care
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Phase 2 Interventional Results available

Tolcapone Treatment of Pathological Gambling

NCT00927563
Conditions
Pathological Gambling
Interventions
Tolcapone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Phase 2 Interventional Results available

Genetic Effects on Dopamine Response to an Opiate

NCT01878006
Conditions
Polymorphism-Genetic, Pain, Addiction
Interventions
Morphine, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Practicing Self-Control Lowers the Risk of Smoking Lapse

NCT00349687
Conditions
Behavior, Addictive, Cigarette Smoking
Interventions
self-control practice
Behavioral
Lead sponsor
University at Albany
Other
Eligibility
18 Years to 45 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Albany, New York
Conditions
Alcohol Use Disorder
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Conditions
Anxiety Disorders, Mood Disorders
Interventions
Single Diagnosis Treatment Protocol, Unified Protocol (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cigarette Smoking, Addiction, E Cig Use
Interventions
E cigarettes, Nicotine Replacement Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Body Acceptance Programs for Young Men

NCT05258409
Conditions
Body Image Disturbance, Eating Disorder Symptom, Eating Behavior, Dysmorphic Features, Dysmorphic Disorder, Body, Dysmorphia, Eating Disorders, Exercise, Compulsive
Interventions
Media Advocacy (MA), More than Muscles (MTM)
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Conditions
Smoking, Smoking Cessation, Craving, Addiction, Addiction Nicotine, Nicotine Dependence, Cigarette Smoking
Interventions
Real TBS to the vmPFC, Sham cTBS to the vmPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions
Collaborative Care Model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Trichotillomania
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional

Nicotine TMS EFT Smoking Pilot Study

NCT03579953
Conditions
Smoking, Nicotine Dependence, Addiction, Smoking, Cigarette
Interventions
Real cTBS, Sham cTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Lodge First Face Training Evaluation Study

NCT06290180
Conditions
Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
Interventions
First Face for Mental Heatlh
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Spokane Valley, Washington
Conditions
Cocaine Abuse, Cocaine-Related Disorders
Interventions
Pregabalin, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
West Haven, Connecticut
Completed No phase listed Observational Accepts healthy volunteers

To Test a Payer/Treatment Agency Intervention to Increase Use of Buprenorphine

NCT01702142
Conditions
Addiction
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
17 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers

NCT01779024
Conditions
fMRI, Alcohol Drinking, Alcoholism
Interventions
Ghrelin, Placebo, fMRI, Alcohol
Drug · Procedure
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Phase 2 Interventional Results available

Memantine in Body Focused Repetitive Behaviors

NCT04792645
Conditions
Trichotillomania (Hair-Pulling Disorder), Dermatillomania
Interventions
Placebo, Memantine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois