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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:58 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 365 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Obsessive Compulsive Disorder (OCD) Clear all

Conditions: Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking
Interventions: Guanfacine Extended Release, Placebo; Drug · Other
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 6 Years to 35 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Obsessive Compulsive Disorder, Stepped Care Cognitive Behavioral Therapy
Interventions: Stepped Care Cognitive Behavioral Therapy, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 8 Years to 17 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Obsessive-Compulsive Disorder
Interventions: Summit RC+S System, One Month Blinded Discontinuation Period:; Device · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 21 Years to 70 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas

Conditions: Obsessive-Compulsive Disorder
Interventions: Medtronic Activa Deep Brain Stimulation; Device
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2012
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obsessive-Compulsive Disorder
Interventions: Exposure and Ritual Prevention (Cognitive Behavioral Therapy), Stress Management Therapy (Cognitive Behavior Therapy); Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 70 Years
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2007
U.S. locations: 2
States / cities: New York, New York • Philadelphia, Pennsylvania

Conditions: Substance Use, Deliberate Self-harm, Trichotillomania, Aggression, Stealing, Eating Pathology, Gambling
Interventions: Surf the Urge; Behavioral
Lead sponsor: Kimberly N Schubert; Other
Eligibility: 14 Years to 24 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions: Serotonergic Psychedelic, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Hamden, Connecticut • West Haven, Connecticut

Conditions: Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD, Generalized Anxiety Disorder (GAD)
Interventions: Not listed
Lead sponsor: Psyrin Inc.; Industry
Eligibility: 18 Years to 68 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Sunnyvale, California • New York, New York

Conditions: Obsessive-Compulsive Disorder
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Tourette's Disorder
Interventions: Omega-3 Fatty Acids, Olive oil; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 6 Years to 18 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1,431 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obsessive-Compulsive Disorder
Interventions: Psilocybin; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Interventions: Memantine, ComB Behavioral Therapy; Drug · Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obsessive-Compulsive Disorder
Interventions: Active tDCS, Sham tDCS; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 60 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obsessive Compulsive Disorder, Major Depressive Disorder, Anxiety
Interventions: Not listed
Lead sponsor: University of Florida; Other
Eligibility: 8 Years to 20 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Trichotillomania
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 75 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders, Somatic Disorders, Obsessive Compulsive Disorders, Eating Disorders, Difficulties With Cognitive Emotion Regulation
Interventions: Cognitive Restructuring, rTMS, Sham rTMS; Behavioral · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obsessive Compulsive Disorder
Interventions: Duloxetine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hoarding Disorder, Hoarding, Clutter
Interventions: Facilitated group therapy with behavioral practice; 18 weeks; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Stanford, California

Conditions: Tourette Syndrome, Obsessive Compulsive Disorder
Interventions: Not listed
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 12 Years to 45 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1988
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorder, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions: Cognitive Behavioral Therapy-Email (iCBT-E), Cognitive Behavioral Therapy-Email and Videoconferencing (iCBT-EV); Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 15 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Generalized Anxiety Disorder
Interventions: Pilot Virtual Reality; Other
Lead sponsor: Minnesota HealthSolutions; Industry
Eligibility: 7 Years to 12 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Eating Disorders
Interventions: Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions; Behavioral
Lead sponsor: Matthew Southward, PhD; Other
Eligibility: 18 Years and older
Enrollment: 390 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obsessive-Compulsive Disorder
Interventions: No Intervention; Other
Lead sponsor: ProgenaBiome; Other
Eligibility: Not listed
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Ventura, California

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Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome

Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder

Development of Adaptive Deep Brain Stimulation for OCD

Electrical Stimulation of the Internal Capsule for Intractable Obsessive-compulsive Disorder (OCD)

Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder

Evaluation of a Brief Surf the Urge Intervention

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

Study of Memantine Augmentation in Severe Obsessive-Compulsive Disorder

Omega-3 Fatty Acids in Tourette's Disorder

Evaluating the Effects of Stress in Pregnancy

Effects of Repeated Psilocybin Dosing in OCD

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic

Naltrexone in the Treatment of Trichotillomania

Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study

Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)

Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice

Study of the Neurobiology of Tourette Syndrome and Related Disorders

Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD

Pilot Study of Virtual Reality for Providing Exposure Therapy to Children

A Precision Medicine Approach to Target Engagement for Emotion Regulation

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obsessive-Compulsive Disorder