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ClinicalTrials.gov public records Last synced Oct 29, 2026, 6:06 AM EDT

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Showing 385–408 of 450 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-Compulsive Behavior Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time

NCT06705179
View directory record Official record
Conditions
Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
Interventions
Behavioral task performance
Behavioral
Lead sponsor
California Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 29, 2026, 6:06 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

NCT03745339
View directory record Official record
Conditions
Opioid-Related Disorders, Drug Addiction
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 29, 2026, 6:06 AM EDT
Terminated Phase 2 Interventional Results available

Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy

NCT01813019
View directory record Official record
Conditions
Patient Diagnosed With OCD and Resistant to SSRI Treatment, Failed SSRI Over 12 Weeks at Appropriate Doses
Interventions
AFQ056, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
San Diego, California • Watertown, Massachusetts • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2017 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional

A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder

NCT00126282
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
behavior therapy, D-Cycloserine
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
2
States / cities
Hartford, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2009 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders

NCT01104805
View directory record Official record
Conditions
Substance Abuse
Interventions
Therapeutic Education System (TES), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
10
States / cities
Danbury, Connecticut • Orlando, Florida • Waipahu, Hawaii + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 29, 2026, 6:06 AM EDT
Not yet recruiting No phase listed Observational

Locating Biomarkers in OCD Through Behavioral Tasks

NCT03313622
View directory record Official record
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Beads Task, PROVOC Tasks
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)

NCT02966873
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
Interventions
N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule, Functional magnetic resonance imaging (fMRI), Proton magnetic resonance spectroscopy (MRS) Imaging
Drug · Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluating Improvement Strategies in Addiction Treatment

NCT00934141
View directory record Official record
Conditions
Addiction
Interventions
Learning Session, Interest Circle Calls, Coaching, Website
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Not listed
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Contingency Management for Hoarding Disorder

NCT04894851
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Contingency Management
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 29, 2026, 6:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hippocampal Neurogenesis in Human Subjects

NCT02028273
View directory record Official record
Conditions
Hippocampal Neurogenesis in Cocaine Addiction
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

NCT00748761
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive Behavioral Therapy (CBT), Waitlist
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Years to 18 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 29, 2026, 6:06 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)

NCT00211822
View directory record Official record
Conditions
Pathological Gambling, Obsessive Compulsive Disorder
Interventions
fMRI
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2011 · Synced Oct 29, 2026, 6:06 AM EDT
Completed No phase listed Observational

Genetics of Obsessive-Compulsive Disorder

NCT00001548
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 29, 2026, 6:06 AM EDT
Completed No phase listed Observational

A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings ("CDE-EHR-PC" Study), Phase 1

NCT02974335
View directory record Official record
Conditions
Addiction
Interventions
Interviews with Stakeholders
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Oct 29, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder

NCT06987526
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Mindfulness-Based Relapse Prevention
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Macon, Georgia • Winder, Georgia
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 29, 2026, 6:06 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical Verification

NCT05440721
View directory record Official record
Conditions
Nicotine Addiction, Drug Addiction, Drug Dependence, Substance Use Disorder, Tobacco Dependence
Interventions
Treatment A with device Clickotine® (Active intervention), Treatment B with smoking education (control)
Device
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 29, 2026, 6:06 AM EDT
Active, not recruiting Not applicable Interventional

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care

NCT04601064
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions
Collaborative Care Model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 29, 2026, 6:06 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Cannabis' Impact on Alcohol Consumption

NCT05389930
View directory record Official record
Conditions
Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
Interventions
THC-dominant cannabis, CBD-dominant cannabis, Cannabis placebo, Alcohol, Alcohol placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years to 50 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

NCT04159571
View directory record Official record
Conditions
Smoking, Smoking Cessation, Craving, Addiction, Addiction Nicotine, Nicotine Dependence, Cigarette Smoking
Interventions
Real TBS to the vmPFC, Sham cTBS to the vmPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 29, 2026, 6:06 AM EDT
Completed No phase listed Observational

Physiological Brain Atlas Development

NCT01210534
View directory record Official record
Conditions
Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder, Depression
Interventions
No intervention
Other
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 90 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse

NCT00220597
View directory record Official record
Conditions
Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior, Sexually Transmitted Diseases, Viral
Interventions
Trauma-focused group therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced Oct 29, 2026, 6:06 AM EDT
Not listed Not applicable Interventional

A RCT of an AEBT Website for Adults With Skin Picking

NCT05989737
View directory record Official record
Conditions
Excoriation (Skin-Picking) Disorder
Interventions
Acceptance-Enhanced Behavior Therapy
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 29, 2026, 6:06 AM EDT
Not listed Not applicable Interventional

Improving Access to Child Anxiety Treatment

NCT03528109
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder
Interventions
Exposure Therapy
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Oct 29, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

NCT00249457
View directory record Official record
Conditions
Behavior, Addictive, Cocaine Abuse, Cocaine Dependence, Heroin Dependence, Opioid Dependence
Interventions
Contingency management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Oct 29, 2026, 6:06 AM EDT