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Showing 121–144 of 450 matching trials from the live ClinicalTrials.gov search.
Conditions
Opioid-use Disorder
Interventions
DBS of the NAc
Device
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Not yet recruiting No phase listed Observational

Locating Biomarkers in OCD Through Behavioral Tasks

NCT03313622
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Beads Task, PROVOC Tasks
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Conditions
Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
Interventions
Varenicline, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Cocaine Dependence, Opiate Dependence
Interventions
Atomoxetine, low dose, Atomoxetine, high dose, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Completed Not applicable Interventional Results available

Patient-Centered Models of HCV Care for People Who Inject Drugs

NCT02824640
Conditions
Hepatitis C, Medication Adherence
Interventions
Patient Navigation, modified Directly Observed Therapy
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 70 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Accepts healthy volunteers

Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder

NCT01368510
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Intensive Cognitive Behavioral Therapy (CBT), Waitlist
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Obsessive-Compulsive Disorder
Interventions
Risperidone, Exposure/ritual prevention therapy (EX/RP), Placebo
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

W8Loss2Go: mHealth Weight Management Strategy

NCT02689154
Conditions
Obesity
Interventions
W8Loss2Go
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Pediatric Obesity, Mobile Technology, Addiction
Interventions
App, Coaching, Clinic: Modified KidsNFitness
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 18 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Not listed Not applicable Interventional Accepts healthy volunteers

90-Day Online Substance Use Program

NCT03069118
Conditions
Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
Interventions
Treatment - Workit Health Online Program, Control - Resource List
Behavioral
Lead sponsor
Workit Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
HIV
Interventions
computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education
Procedure
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
13 Years to 18 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Conditions
Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester, Alcohol Use Complicating Pregnancy, Second Trimester, Alcohol Use Complicating Pregnancy, Third Trimester, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Alcohol Use Complicating Pregnancy, Childbirth, and the Puerperium, Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Drug Use Disorders, Drug Use Complicating Pregnancy, First Trimester, Drug Use Complicating Pregnancy, Second Trimester, Drug Use Complicating Pregnancy, Third Trimester, Drug Use Complicating Pregnancy, Unspecified Trimester, Drug Use Complicating Pregnancy, Childbirth, and the Puerperium, Maternal Drugs Affecting Fetus
Interventions
Parent-Child Assistance Program
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Tulsa, Oklahoma
Conditions
Obsessive-Compulsive Disorder
Interventions
Motivational interviewing plus exposure and response prevention (MI plus EX/RP), Exposure and response prevention (EX/RP)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Conditions
Food Addiction
Interventions
16-week Food Addiction Clinical Treatment (FACT) Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
25 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings

NCT02893514
Conditions
Addiction
Interventions
Screening Only (SO) condition, SUSIT Condition
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Stepped Care CBT
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Opioid Dependence
Interventions
BEMA Buprenorphine NX films
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
10
States / cities
Birmingham, Alabama • Haleyville, Alabama • Jacksonville, Florida + 7 more
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

VK4-116 Phase I Study With Food-Effect

NCT06808932
Conditions
Opioid Dependence, Opioid Use Disorder (OUD)
Interventions
VK4-116, Placebo
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Overland Park, Kansas
Completed Phase 2 Interventional Results available

Genetic Effects on Dopamine Response to an Opiate

NCT01878006
Conditions
Polymorphism-Genetic, Pain, Addiction
Interventions
Morphine, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Addiction, Substance Abuse, Cannabis Use Disorder, Cannabis Use, Cannabis Dependence, Cannabis Abuse
Interventions
Breathwork workshop
Behavioral
Lead sponsor
Elias Dakwar
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Completed Phase 2 Interventional Results available

Enhancing Attention in Adults With Compulsive Hoarding

NCT01100268
Conditions
Hoarding Disorder
Interventions
Methylphenidate ER
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Hartford, Connecticut • New York, New York
Completed Not applicable Interventional Results available

Cognitive Effects of Atomoxetine in Humans: Genetic Moderators

NCT01498549
Conditions
Addiction
Interventions
Atomoxetine, Sugar Pill
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Food Addiction
Interventions
telomere length measure
Diagnostic Test
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 70 Years
Enrollment
120 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Scottsbluff, Nebraska
Conditions
Opioid Use Disorder
Interventions
Youth Opioid Recovery Support (YORS)
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
13 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland