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Showing 1–24 of 363 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obsessive-Compulsive Disorder Clear all
Completed Phase 2 Interventional Results available

Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder

NCT00215137
View directory record Official record
Conditions
OCD
Interventions
escitalopram, Placebo ( sugar pill)
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Methods for Managing Intrusive Thoughts

NCT03416504
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Gradual Exposure (EXP-G), Variable Exposure (EXP-V)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 4, 2026, 2:47 PM EDT
Active, not recruiting Not applicable Interventional

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

NCT07024758
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder, Panic Disorder, Panic Attacks, Panic Disorder (With or Without Agoraphobia), Phobia, Specific
Interventions
Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Characterization of Childhood-Onset Obsessive-Compulsive Disorder

NCT00044239
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
4 Years to 12 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2010
U.S. locations
4
States / cities
Little Rock, Arkansas • Gainesville, Florida • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 4, 2026, 2:47 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Neural Mechanisms of Decision Making in Hoarding Disorder

NCT03487224
View directory record Official record
Conditions
Hoarding Disorder
Interventions
MRI with fMRI frequency
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder

NCT04641143
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Troriluzole, Placebo
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
73
States / cities
Chandler, Arizona • Phoenix, Arizona • Bellflower, California + 62 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Light Therapy for Obsessive-compulsive Disorder (OCD)

NCT05391503
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Light therapy, Placebo light therapy
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 35 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Phase 2 Interventional Results available

Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania

NCT01654523
View directory record Official record
Conditions
Trichotillomania
Interventions
Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 21, 2016 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents

NCT01177969
View directory record Official record
Conditions
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Interventions
Cognitive-Behavioral Therapy, Wait-list
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
11 Years to 14 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Los Angeles, California • St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Sep 4, 2026, 2:47 PM EDT
Completed No phase listed Observational

Augmentation in Tx-resistant OCD: an Open Label Trial

NCT00590642
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 30, 2009 · Synced Sep 4, 2026, 2:47 PM EDT
Active, not recruiting Not applicable Interventional

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

NCT06138782
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Recruiting Phase 2 Interventional

SONATA LIFU for OCD

NCT07728994
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Low Intensity Focused Ultrasound, Sham (No Treatment)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Phase 2 Interventional Results available

Naltrexone in the Treatment of Trichotillomania

NCT00775229
View directory record Official record
Conditions
Trichotillomania
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 4, 2026, 2:47 PM EDT
Completed No phase listed Observational

Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease

NCT04688554
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Pain, Intractable, Depression
Interventions
fMRI and DTI, Behavioral questionnaires, Disease-Specific Patient-Reported Outcomes, Behavioral tests
Diagnostic Test · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 4, 2026, 2:47 PM EDT
Active, not recruiting Phase 2 Interventional

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

NCT05624528
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, OCD
Interventions
Tolcapone, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 4, 2026, 2:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Precision Analytic Research Methods in OCD

NCT07011901
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Exposure and Response Prevention
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Comprehensive Behavioral (ComB) Model of Treatment for Trichotillomania

NCT03486041
View directory record Official record
Conditions
Trichotillomania
Interventions
Comprehensive Behavior Modification, Attention
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children

NCT03584945
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms in Children
Interventions
Cognitive Behavioral Therapy, Community Referral as appropriate
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 14 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 4, 2026, 2:47 PM EDT
Recruiting Not applicable Interventional

Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder

NCT07146438
View directory record Official record
Conditions
Obsessive - Compulsive Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Supportive Therapy (ST), Exposure and Response Prevention (ERP) Therapy
Device · Behavioral
Lead sponsor
Adam Frank
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Response Inhibition Training for Individuals With Trichotillomania

NCT01638975
View directory record Official record
Conditions
Trichotillomania
Interventions
Response Inhibition Training Program
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
9 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 19, 2014 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional Results available

Stepped Care for Treating Obsessive-Compulsive Disorder

NCT00316355
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Traditional CBT, Stepped-Care CBT
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 69 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 21, 2018 · Synced Sep 4, 2026, 2:47 PM EDT
Completed Not applicable Interventional

Enhancement of Therapeutic Learning in OCD Using tDCS

NCT03572543
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
tDCS
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Sep 4, 2026, 2:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2013 · Synced Sep 4, 2026, 2:47 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery

NCT02320266
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced Sep 4, 2026, 2:47 PM EDT